Name | Number of supported studies | Average coverage | |
---|---|---|---|
classical monocyte | 14 studies | 23% ± 7% | |
naive thymus-derived CD4-positive, alpha-beta T cell | 10 studies | 20% ± 4% | |
regulatory T cell | 10 studies | 19% ± 5% | |
naive thymus-derived CD8-positive, alpha-beta T cell | 8 studies | 19% ± 6% | |
CD4-positive, alpha-beta T cell | 8 studies | 22% ± 6% | |
plasmacytoid dendritic cell | 8 studies | 24% ± 6% | |
endothelial cell | 6 studies | 20% ± 4% | |
B cell | 5 studies | 19% ± 2% | |
naive B cell | 5 studies | 18% ± 3% | |
T cell | 4 studies | 22% ± 7% | |
non-classical monocyte | 4 studies | 26% ± 5% | |
conventional dendritic cell | 4 studies | 29% ± 13% | |
CD8-positive, alpha-beta T cell | 4 studies | 22% ± 7% | |
T follicular helper cell | 4 studies | 21% ± 3% | |
CD4-positive, alpha-beta memory T cell | 3 studies | 19% ± 4% | |
epithelial cell | 3 studies | 30% ± 9% | |
ciliated cell | 3 studies | 28% ± 3% | |
macrophage | 3 studies | 19% ± 2% | |
glutamatergic neuron | 3 studies | 26% ± 4% | |
dendritic cell | 3 studies | 34% ± 9% | |
monocyte | 3 studies | 16% ± 1% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
peripheral blood | 9 studies | 20% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 2008.71 | 21 / 21 | 100% | 11.32 | 504 / 504 |
esophagus | 100% | 1991.03 | 1445 / 1445 | 100% | 11.10 | 183 / 183 |
intestine | 100% | 2412.17 | 966 / 966 | 100% | 10.78 | 527 / 527 |
lung | 100% | 3246.95 | 578 / 578 | 100% | 11.17 | 1155 / 1155 |
ovary | 100% | 1627.93 | 180 / 180 | 100% | 11.02 | 430 / 430 |
breast | 100% | 2347.89 | 459 / 459 | 100% | 11.92 | 1117 / 1118 |
prostate | 100% | 2129.46 | 245 / 245 | 100% | 8.86 | 501 / 502 |
uterus | 100% | 1988.54 | 170 / 170 | 100% | 13.27 | 458 / 459 |
stomach | 100% | 1485.18 | 358 / 359 | 100% | 10.86 | 286 / 286 |
brain | 100% | 1645.41 | 2632 / 2642 | 100% | 11.19 | 705 / 705 |
thymus | 100% | 2239.07 | 653 / 653 | 99% | 10.66 | 601 / 605 |
kidney | 100% | 1563.13 | 89 / 89 | 99% | 8.00 | 890 / 901 |
skin | 100% | 2151.80 | 1809 / 1809 | 97% | 10.05 | 459 / 472 |
adrenal gland | 100% | 1490.59 | 258 / 258 | 95% | 5.74 | 219 / 230 |
pancreas | 96% | 861.13 | 315 / 328 | 99% | 10.08 | 176 / 178 |
liver | 100% | 953.83 | 226 / 226 | 93% | 4.47 | 377 / 406 |
adipose | 100% | 2398.23 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 22.73 | 29 / 29 |
muscle | 100% | 2168.88 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 6699.25 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 12.62 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 4.21 | 1 / 1 |
peripheral blood | 100% | 9607.51 | 928 / 929 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2027.78 | 1333 / 1335 | 0% | 0 | 0 / 0 |
heart | 98% | 1047.81 | 842 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 83% | 4.55 | 66 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006325 | Biological process | chromatin organization |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_0006355 | Biological process | regulation of DNA-templated transcription |
GO_0005654 | Cellular component | nucleoplasm |
GO_0072487 | Cellular component | MSL complex |
GO_0035267 | Cellular component | NuA4 histone acetyltransferase complex |
GO_0005634 | Cellular component | nucleus |
GO_0035064 | Molecular function | methylated histone binding |
GO_0003677 | Molecular function | DNA binding |
GO_0140566 | Molecular function | histone reader activity |
GO_0005515 | Molecular function | protein binding |
Gene name | MSL3 |
Protein name | MSL complex subunit 3 Male-specific lethal 3 homolog (Male-specific lethal-3 homolog 1) (Male-specific lethal-3 protein-like 1) (MSL3-like 1) |
Synonyms | MSL3L1 |
Description | FUNCTION: Has a role in chromatin remodeling and transcriptional regulation . Has a role in X inactivation . Component of the MSL complex which is responsible for the majority of histone H4 acetylation at 'Lys-16' which is implicated in the formation of higher-order chromatin structure . Specifically recognizes histone H4 monomethylated at 'Lys-20' (H4K20Me1) in a DNA-dependent manner and is proposed to be involved in chromosomal targeting of the MSL complex . . |
Accessions | ENST00000649271.1 [Q8N5Y2-4] ENST00000647599.1 A0A3B3IRI6 H7BYE4 ENST00000361672.6 [Q8N5Y2-6] A0A3B3IRN2 A0A3B3IUB0 A0A3B3IT59 A0A3B3IS16 A0A3B3ITX5 A0A3B3ITF8 A0A3B3IU80 A0A3B3IS72 ENST00000650106.1 ENST00000649797.1 ENST00000649649.1 [Q8N5Y2-6] ENST00000649130.1 ENST00000468149.5 ENST00000650215.1 [Q8N5Y2-6] ENST00000650370.1 ENST00000398527.7 [Q8N5Y2-3] ENST00000650628.1 [Q8N5Y2-4] ENST00000648013.1 [Q8N5Y2-4] ENST00000483645.6 ENST00000337339.7 [Q8N5Y2-5] A0A3B3IRT2 A0A3F2YNX2 ENST00000649685.1 [Q8N5Y2-6] ENST00000647839.1 A0A3B3ISB4 ENST00000648614.1 ENST00000649851.1 ENST00000380692.7 ENST00000647869.1 ENST00000648287.1 ENST00000648120.1 A0A3B3ITV8 ENST00000648545.1 Q8N5Y2 ENST00000482871.6 [Q8N5Y2-4] ENST00000649785.1 ENST00000312196.10 [Q8N5Y2-1] ENST00000647857.1 ENST00000649602.1 [Q8N5Y2-4] ENST00000648692.1 ENST00000649078.1 [Q8N5Y2-4] F8WC61 A0A3B3IU64 ENST00000476743.5 A6NLU8 ENST00000649420.1 ENST00000380693.8 C9JKR8 C9JXM9 ENST00000648656.1 A0A3B3ITH5 A0A3B3IU53 ENST00000421368.3 A0A3B3ITF3 ENST00000380691.3 A0A3B3IT49 ENST00000467141.2 A0A3B3ITL5 |