MSL3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006325Biological processchromatin organization
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0006355Biological processregulation of DNA-templated transcription
GO_0005654Cellular componentnucleoplasm
GO_0072487Cellular componentMSL complex
GO_0035267Cellular componentNuA4 histone acetyltransferase complex
GO_0005634Cellular componentnucleus
GO_0035064Molecular functionmethylated histone binding
GO_0003677Molecular functionDNA binding
GO_0140566Molecular functionhistone reader activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameMSL3
Protein nameMSL complex subunit 3
Male-specific lethal 3 homolog (Male-specific lethal-3 homolog 1) (Male-specific lethal-3 protein-like 1) (MSL3-like 1)
SynonymsMSL3L1
DescriptionFUNCTION: Has a role in chromatin remodeling and transcriptional regulation . Has a role in X inactivation . Component of the MSL complex which is responsible for the majority of histone H4 acetylation at 'Lys-16' which is implicated in the formation of higher-order chromatin structure . Specifically recognizes histone H4 monomethylated at 'Lys-20' (H4K20Me1) in a DNA-dependent manner and is proposed to be involved in chromosomal targeting of the MSL complex . .

AccessionsENST00000649271.1 [Q8N5Y2-4]
ENST00000647599.1
A0A3B3IRI6
H7BYE4
ENST00000361672.6 [Q8N5Y2-6]
A0A3B3IRN2
A0A3B3IUB0
A0A3B3IT59
A0A3B3IS16
A0A3B3ITX5
A0A3B3ITF8
A0A3B3IU80
A0A3B3IS72
ENST00000650106.1
ENST00000649797.1
ENST00000649649.1 [Q8N5Y2-6]
ENST00000649130.1
ENST00000468149.5
ENST00000650215.1 [Q8N5Y2-6]
ENST00000650370.1
ENST00000398527.7 [Q8N5Y2-3]
ENST00000650628.1 [Q8N5Y2-4]
ENST00000648013.1 [Q8N5Y2-4]
ENST00000483645.6
ENST00000337339.7 [Q8N5Y2-5]
A0A3B3IRT2
A0A3F2YNX2
ENST00000649685.1 [Q8N5Y2-6]
ENST00000647839.1
A0A3B3ISB4
ENST00000648614.1
ENST00000649851.1
ENST00000380692.7
ENST00000647869.1
ENST00000648287.1
ENST00000648120.1
A0A3B3ITV8
ENST00000648545.1
Q8N5Y2
ENST00000482871.6 [Q8N5Y2-4]
ENST00000649785.1
ENST00000312196.10 [Q8N5Y2-1]
ENST00000647857.1
ENST00000649602.1 [Q8N5Y2-4]
ENST00000648692.1
ENST00000649078.1 [Q8N5Y2-4]
F8WC61
A0A3B3IU64
ENST00000476743.5
A6NLU8
ENST00000649420.1
ENST00000380693.8
C9JKR8
C9JXM9
ENST00000648656.1
A0A3B3ITH5
A0A3B3IU53
ENST00000421368.3
A0A3B3ITF3
ENST00000380691.3
A0A3B3IT49
ENST00000467141.2
A0A3B3ITL5