MPLKIP report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
B cell	15 studies	21% ± 8%	Explore
endothelial cell	13 studies	24% ± 10%	Explore
fibroblast	12 studies	21% ± 6%	Explore
natural killer cell	9 studies	19% ± 5%	Explore
epithelial cell	8 studies	38% ± 21%	Explore
ciliated cell	8 studies	33% ± 13%	Explore
classical monocyte	6 studies	24% ± 9%	Explore
conventional dendritic cell	6 studies	30% ± 16%	Explore
connective tissue cell	6 studies	23% ± 6%	Explore
smooth muscle cell	6 studies	18% ± 3%	Explore
basal cell	6 studies	31% ± 15%	Explore
CD4-positive, alpha-beta T cell	5 studies	20% ± 4%	Explore
epithelial cell of proximal tubule	5 studies	19% ± 3%	Explore
pericyte	5 studies	21% ± 6%	Explore
CD8-positive, alpha-beta T cell	5 studies	18% ± 5%	Explore
regulatory T cell	5 studies	19% ± 4%	Explore
abnormal cell	5 studies	23% ± 8%	Explore
plasmacytoid dendritic cell	5 studies	25% ± 8%	Explore
hematopoietic precursor cell	4 studies	31% ± 12%	Explore
non-classical monocyte	4 studies	27% ± 6%	Explore
myofibroblast cell	4 studies	20% ± 1%	Explore
progenitor cell	4 studies	17% ± 1%	Explore
monocyte	4 studies	19% ± 4%	Explore
memory B cell	4 studies	17% ± 1%	Explore
naive B cell	4 studies	20% ± 3%	Explore
precursor B cell	4 studies	30% ± 12%	Explore
neuron	4 studies	27% ± 14%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	18% ± 1%	Explore
mature NK T cell	3 studies	18% ± 1%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	22% ± 3%	Explore
T cell	3 studies	21% ± 3%	Explore
neural crest cell	3 studies	25% ± 2%	Explore
vein endothelial cell	3 studies	16% ± 1%	Explore
capillary endothelial cell	3 studies	18% ± 1%	Explore
immature B cell	3 studies	20% ± 2%	Explore
pro-B cell	3 studies	29% ± 2%	Explore
erythroblast	3 studies	32% ± 22%	Explore
endothelial cell of vascular tree	3 studies	18% ± 2%	Explore
exhausted T cell	3 studies	16% ± 1%	Explore
glutamatergic neuron	3 studies	24% ± 8%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	38% ± 20%	Explore
enteroendocrine cell	3 studies	28% ± 14%	Explore
goblet cell	3 studies	26% ± 10%	Explore
intestinal crypt stem cell	3 studies	25% ± 3%	Explore
secretory cell	3 studies	27% ± 12%	Explore
oligodendrocyte precursor cell	3 studies	24% ± 2%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
lung	6 studies	28% ± 10%	Explore
peripheral blood	5 studies	23% ± 8%	Explore
intestine	5 studies	23% ± 11%	Explore
brain	5 studies	18% ± 2%	Explore
kidney	4 studies	16% ± 1%	Explore
liver	3 studies	34% ± 22%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	956.88	1445 / 1445	100%	12.23	183 / 183
liver	100%	1521.73	226 / 226	100%	16.88	406 / 406
ovary	100%	1060.49	180 / 180	100%	12.40	430 / 430
skin	100%	1397.80	1809 / 1809	100%	12.59	472 / 472
stomach	100%	736.22	359 / 359	100%	13.49	286 / 286
uterus	100%	1046.69	170 / 170	100%	13.92	459 / 459
breast	100%	1165.09	459 / 459	100%	11.01	1117 / 1118
kidney	100%	1276.73	89 / 89	100%	10.23	900 / 901
thymus	100%	1270.84	653 / 653	100%	11.70	604 / 605
lung	100%	868.65	577 / 578	100%	12.54	1155 / 1155
intestine	100%	1012.29	966 / 966	100%	15.05	526 / 527
bladder	100%	960.43	21 / 21	100%	14.35	503 / 504
brain	100%	885.40	2636 / 2642	100%	11.55	705 / 705
pancreas	100%	627.45	327 / 328	100%	9.93	178 / 178
prostate	100%	1030.66	245 / 245	100%	11.73	500 / 502
adrenal gland	100%	1428.14	258 / 258	99%	10.10	227 / 230
adipose	100%	1124.43	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	8.44	80 / 80
lymph node	0%	0	0 / 0	100%	16.30	29 / 29
spleen	100%	1215.73	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	11.55	45 / 45
ureter	0%	0	0 / 0	100%	8.14	1 / 1
blood vessel	100%	955.09	1334 / 1335	0%	0	0 / 0
muscle	99%	547.96	795 / 803	0%	0	0 / 0
heart	99%	527.93	850 / 861	0%	0	0 / 0
peripheral blood	95%	819.12	884 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0