Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 20 studies | 30% ± 10% | |
ciliated cell | 16 studies | 36% ± 13% | |
oligodendrocyte precursor cell | 13 studies | 41% ± 15% | |
astrocyte | 13 studies | 36% ± 16% | |
glutamatergic neuron | 12 studies | 59% ± 24% | |
microglial cell | 12 studies | 26% ± 11% | |
fibroblast | 12 studies | 27% ± 7% | |
GABAergic neuron | 11 studies | 50% ± 24% | |
oligodendrocyte | 11 studies | 33% ± 10% | |
natural killer cell | 9 studies | 20% ± 5% | |
adipocyte | 9 studies | 48% ± 10% | |
smooth muscle cell | 9 studies | 24% ± 10% | |
basal cell | 8 studies | 33% ± 12% | |
pericyte | 7 studies | 26% ± 7% | |
epithelial cell | 7 studies | 39% ± 14% | |
neuron | 6 studies | 41% ± 17% | |
interneuron | 6 studies | 59% ± 25% | |
macrophage | 6 studies | 22% ± 5% | |
retinal cone cell | 6 studies | 29% ± 7% | |
type I pneumocyte | 6 studies | 27% ± 8% | |
type II pneumocyte | 6 studies | 27% ± 8% | |
club cell | 6 studies | 31% ± 12% | |
CD16-positive, CD56-dim natural killer cell, human | 5 studies | 19% ± 4% | |
retinal ganglion cell | 5 studies | 44% ± 24% | |
amacrine cell | 5 studies | 37% ± 12% | |
retina horizontal cell | 5 studies | 30% ± 13% | |
retinal rod cell | 5 studies | 26% ± 6% | |
cardiac muscle cell | 5 studies | 29% ± 6% | |
Mueller cell | 5 studies | 32% ± 11% | |
endothelial cell of lymphatic vessel | 5 studies | 23% ± 6% | |
CD16-negative, CD56-bright natural killer cell, human | 4 studies | 24% ± 2% | |
granule cell | 4 studies | 39% ± 16% | |
progenitor cell | 4 studies | 25% ± 7% | |
retinal bipolar neuron | 4 studies | 29% ± 11% | |
mesothelial cell | 4 studies | 29% ± 8% | |
T cell | 4 studies | 18% ± 3% | |
respiratory goblet cell | 4 studies | 36% ± 12% | |
GABAergic interneuron | 3 studies | 46% ± 12% | |
glial cell | 3 studies | 22% ± 2% | |
lymphocyte | 3 studies | 31% ± 8% | |
GABAergic amacrine cell | 3 studies | 48% ± 12% | |
OFF-bipolar cell | 3 studies | 32% ± 11% | |
ON-bipolar cell | 3 studies | 33% ± 13% | |
glycinergic amacrine cell | 3 studies | 39% ± 9% | |
rod bipolar cell | 3 studies | 31% ± 12% | |
endothelial cell of vascular tree | 3 studies | 21% ± 5% | |
hepatocyte | 3 studies | 38% ± 13% | |
muscle cell | 3 studies | 34% ± 10% | |
CD8-positive, alpha-beta T cell | 3 studies | 17% ± 1% | |
connective tissue cell | 3 studies | 23% ± 4% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 24% ± 3% | |
chondrocyte | 3 studies | 30% ± 8% | |
gamma-delta T cell | 3 studies | 26% ± 9% | |
plasmacytoid dendritic cell | 3 studies | 34% ± 11% | |
mucus secreting cell | 3 studies | 32% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 863.25 | 459 / 459 | 100% | 13.55 | 1118 / 1118 |
esophagus | 100% | 732.99 | 1445 / 1445 | 100% | 9.83 | 183 / 183 |
ovary | 100% | 891.61 | 180 / 180 | 100% | 10.11 | 430 / 430 |
uterus | 100% | 778.47 | 170 / 170 | 100% | 14.58 | 459 / 459 |
brain | 100% | 787.12 | 2640 / 2642 | 100% | 10.90 | 705 / 705 |
prostate | 100% | 830.83 | 245 / 245 | 100% | 11.03 | 501 / 502 |
thymus | 100% | 715.38 | 653 / 653 | 100% | 10.60 | 602 / 605 |
lung | 99% | 614.28 | 575 / 578 | 100% | 12.07 | 1155 / 1155 |
bladder | 100% | 802.62 | 21 / 21 | 99% | 10.28 | 501 / 504 |
adrenal gland | 100% | 825.78 | 258 / 258 | 99% | 8.51 | 227 / 230 |
kidney | 100% | 735.99 | 89 / 89 | 98% | 6.92 | 886 / 901 |
stomach | 100% | 553.81 | 359 / 359 | 98% | 7.18 | 281 / 286 |
liver | 100% | 353.02 | 225 / 226 | 98% | 5.51 | 397 / 406 |
intestine | 100% | 604.36 | 964 / 966 | 97% | 7.35 | 512 / 527 |
pancreas | 98% | 338.07 | 323 / 328 | 98% | 8.97 | 175 / 178 |
skin | 100% | 802.86 | 1808 / 1809 | 95% | 8.43 | 448 / 472 |
adipose | 100% | 887.24 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1070.55 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 10.95 | 29 / 29 |
muscle | 100% | 1845.18 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 488.91 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 13.13 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.86 | 1 / 1 |
heart | 97% | 566.99 | 835 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 74% | 3.83 | 59 / 80 |
peripheral blood | 45% | 356.63 | 419 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006281 | Biological process | DNA repair |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0048661 | Biological process | positive regulation of smooth muscle cell proliferation |
GO_0006289 | Biological process | nucleotide-excision repair |
GO_2000045 | Biological process | regulation of G1/S transition of mitotic cell cycle |
GO_0021591 | Biological process | ventricular system development |
GO_0043066 | Biological process | negative regulation of apoptotic process |
GO_0007512 | Biological process | adult heart development |
GO_0006367 | Biological process | transcription initiation at RNA polymerase II promoter |
GO_0051592 | Biological process | response to calcium ion |
GO_0000082 | Biological process | G1/S transition of mitotic cell cycle |
GO_0070985 | Cellular component | transcription factor TFIIK complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0000439 | Cellular component | transcription factor TFIIH core complex |
GO_0000307 | Cellular component | cyclin-dependent protein kinase holoenzyme complex |
GO_0070516 | Cellular component | CAK-ERCC2 complex |
GO_0005675 | Cellular component | transcription factor TFIIH holo complex |
GO_0061575 | Molecular function | cyclin-dependent protein serine/threonine kinase activator activity |
GO_0008270 | Molecular function | zinc ion binding |
GO_0005515 | Molecular function | protein binding |
Gene name | MNAT1 |
Protein name | CDK-activating kinase assembly factor MAT1 (CDK7/cyclin-H assembly factor) (Cyclin-G1-interacting protein) (Menage a trois) (RING finger protein 66) (RING finger protein MAT1) (p35) (p36) Menage a trois-like protein 1 cyclin H assembly factor isoform 2 MNAT1 component of CDK activating kinase Menage a trois-like protein 1 cyclin H assembly factor isoform 1 |
Synonyms | CAP35 RNF66 MAT1 |
Description | FUNCTION: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. . |
Accessions | H0YJF2 H0YJ92 ENST00000261245.9 [P51948-1] ENST00000554002.5 A0A024R688 P51948 A0A0S2Z414 ENST00000539616.6 [P51948-2] ENST00000557134.1 |