MLXIP report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005741Cellular componentmitochondrial outer membrane
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0046983Molecular functionprotein dimerization activity
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameMLXIP
Protein nameMLX-interacting protein (Class E basic helix-loop-helix protein 36) (bHLHe36) (Transcriptional activator MondoA)
Alternative protein MLXIP
MLX interacting protein
SynonymsMONDOA
MIR
KIAA0867
BHLHE36
DescriptionFUNCTION: Binds DNA as a heterodimer with MLX and activates transcription. Binds to the canonical E box sequence 5'-CACGTG-3'. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation. .

AccessionsL8EAR3
ENST00000319080.12 [Q9HAP2-1]
ENST00000538698.5 [Q9HAP2-2]
ENST00000625732.3 [Q9HAP2-1]
ENST00000535430.5
F5H321
F5H0V4
ENST00000366272.6
H0YGR9
ENST00000542417.1
Q9HAP2
ENST00000629738.4 [Q9HAP2-1]