Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 46 studies | 46% ± 20% | |
fibroblast | 20 studies | 44% ± 19% | |
astrocyte | 17 studies | 52% ± 17% | |
oligodendrocyte | 16 studies | 75% ± 17% | |
ciliated cell | 13 studies | 36% ± 16% | |
type I pneumocyte | 12 studies | 75% ± 19% | |
glutamatergic neuron | 12 studies | 69% ± 21% | |
endothelial cell of lymphatic vessel | 11 studies | 36% ± 17% | |
type II pneumocyte | 11 studies | 57% ± 22% | |
GABAergic neuron | 11 studies | 58% ± 29% | |
endothelial cell of artery | 9 studies | 32% ± 10% | |
vein endothelial cell | 9 studies | 35% ± 15% | |
adipocyte | 9 studies | 55% ± 17% | |
epithelial cell | 8 studies | 30% ± 8% | |
oligodendrocyte precursor cell | 8 studies | 25% ± 12% | |
smooth muscle cell | 7 studies | 27% ± 6% | |
capillary endothelial cell | 7 studies | 40% ± 16% | |
endothelial cell of vascular tree | 7 studies | 39% ± 20% | |
retinal cone cell | 7 studies | 42% ± 22% | |
kidney distal convoluted tubule epithelial cell | 6 studies | 47% ± 19% | |
neuron | 6 studies | 41% ± 19% | |
interneuron | 6 studies | 62% ± 30% | |
retinal rod cell | 6 studies | 49% ± 24% | |
cardiac muscle cell | 6 studies | 61% ± 23% | |
Mueller cell | 6 studies | 47% ± 15% | |
club cell | 6 studies | 61% ± 21% | |
macrophage | 5 studies | 24% ± 5% | |
microglial cell | 5 studies | 45% ± 14% | |
retinal ganglion cell | 5 studies | 48% ± 20% | |
connective tissue cell | 5 studies | 30% ± 12% | |
myofibroblast cell | 5 studies | 32% ± 8% | |
basal cell | 5 studies | 35% ± 13% | |
endothelial cell of sinusoid | 4 studies | 33% ± 17% | |
glomerular endothelial cell | 4 studies | 54% ± 6% | |
pericyte | 4 studies | 30% ± 9% | |
retinal pigment epithelial cell | 4 studies | 55% ± 21% | |
mesothelial cell | 4 studies | 37% ± 16% | |
OFF-bipolar cell | 4 studies | 36% ± 19% | |
luminal hormone-sensing cell of mammary gland | 4 studies | 30% ± 8% | |
luminal cell of prostate epithelium | 4 studies | 34% ± 19% | |
respiratory goblet cell | 4 studies | 45% ± 21% | |
renal alpha-intercalated cell | 4 studies | 43% ± 19% | |
renal principal cell | 4 studies | 51% ± 23% | |
ionocyte | 3 studies | 26% ± 5% | |
pancreatic A cell | 3 studies | 54% ± 11% | |
type B pancreatic cell | 3 studies | 44% ± 15% | |
cholangiocyte | 3 studies | 42% ± 14% | |
T cell | 3 studies | 44% ± 20% | |
GABAergic interneuron | 3 studies | 67% ± 19% | |
glial cell | 3 studies | 44% ± 18% | |
endocardial cell | 3 studies | 41% ± 8% | |
ON-bipolar cell | 3 studies | 28% ± 5% | |
glycinergic amacrine cell | 3 studies | 43% ± 23% | |
hepatocyte | 3 studies | 32% ± 12% | |
ependymal cell | 3 studies | 57% ± 19% | |
chondrocyte | 3 studies | 41% ± 15% | |
brush cell | 3 studies | 22% ± 5% | |
granule cell | 3 studies | 61% ± 23% | |
enteroendocrine cell | 3 studies | 21% ± 5% | |
secretory cell | 3 studies | 30% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 9432.15 | 2639 / 2642 | 100% | 52.77 | 702 / 705 |
prostate | 100% | 6744.82 | 244 / 245 | 100% | 53.65 | 501 / 502 |
thymus | 100% | 8878.90 | 652 / 653 | 94% | 30.44 | 568 / 605 |
breast | 99% | 4808.94 | 454 / 459 | 88% | 27.43 | 988 / 1118 |
kidney | 98% | 3868.26 | 87 / 89 | 89% | 26.28 | 799 / 901 |
adrenal gland | 100% | 6503.18 | 257 / 258 | 85% | 17.09 | 196 / 230 |
lung | 100% | 20319.97 | 577 / 578 | 75% | 26.83 | 869 / 1155 |
bladder | 86% | 3906.57 | 18 / 21 | 61% | 14.49 | 307 / 504 |
esophagus | 80% | 2990.64 | 1163 / 1445 | 45% | 6.09 | 83 / 183 |
ovary | 77% | 3278.37 | 138 / 180 | 46% | 5.34 | 198 / 430 |
muscle | 100% | 18150.41 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 11725.17 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 19.79 | 1 / 1 |
blood vessel | 100% | 12239.99 | 1329 / 1335 | 0% | 0 | 0 / 0 |
adipose | 97% | 4397.88 | 1172 / 1204 | 0% | 0 | 0 / 0 |
heart | 97% | 9605.17 | 835 / 861 | 0% | 0 | 0 / 0 |
pancreas | 7% | 152.77 | 23 / 328 | 79% | 12.80 | 140 / 178 |
uterus | 29% | 611.02 | 49 / 170 | 56% | 10.55 | 258 / 459 |
intestine | 50% | 1408.91 | 484 / 966 | 32% | 3.62 | 168 / 527 |
skin | 43% | 993.76 | 778 / 1809 | 29% | 5.01 | 136 / 472 |
stomach | 24% | 497.63 | 87 / 359 | 28% | 2.98 | 81 / 286 |
liver | 21% | 457.85 | 47 / 226 | 20% | 3.93 | 80 / 406 |
tonsil | 0% | 0 | 0 / 0 | 22% | 2.53 | 10 / 45 |
eye | 0% | 0 | 0 / 0 | 6% | 0.56 | 5 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0030336 | Biological process | negative regulation of cell migration |
GO_0001934 | Biological process | positive regulation of protein phosphorylation |
GO_0060327 | Biological process | cytoplasmic actin-based contraction involved in cell motility |
GO_0051893 | Biological process | regulation of focal adhesion assembly |
GO_0051496 | Biological process | positive regulation of stress fiber assembly |
GO_0031032 | Biological process | actomyosin structure organization |
GO_0001725 | Cellular component | stress fiber |
GO_0016460 | Cellular component | myosin II complex |
GO_0005737 | Cellular component | cytoplasm |
GO_0032034 | Molecular function | myosin II head/neck binding |
GO_0003779 | Molecular function | actin binding |
GO_0046872 | Molecular function | metal ion binding |
Gene name | LIMCH1 |
Protein name | LIM and calponin homology domains-containing protein 1 LIM and calponin homology domains 1 (LIMCH1 protein) LIM and calponin homology domains 1 |
Synonyms | KIAA1102 hCG_33090 DKFZP686A01247 |
Description | FUNCTION: Actin stress fibers-associated protein that activates non-muscle myosin IIa. Activates the non-muscle myosin IIa complex by promoting the phosphorylation of its regulatory subunit MRLC/MYL9. Through the activation of non-muscle myosin IIa, positively regulates actin stress fibers assembly and stabilizes focal adhesions. It therefore negatively regulates cell spreading and cell migration. . |
Accessions | E9PDJ9 D6RD46 ENST00000381753.8 [Q9UPQ0-9] ENST00000511424.5 ENST00000508466.1 ENST00000513024.5 [Q9UPQ0-5] ENST00000509454.5 ENST00000446625.6 D6RJ93 D6RGH8 Q9UPQ0 D6R8Y0 ENST00000511496.5 [Q9UPQ0-8] ENST00000509277.5 ENST00000514096.5 ENST00000503057.6 H0Y8P3 ENST00000512946.5 [Q9UPQ0-2] ENST00000508501.5 [Q9UPQ0-10] ENST00000313860.12 [Q9UPQ0-1] ENST00000509638.5 ENST00000396595.7 [Q9UPQ0-6] ENST00000512632.5 E7EPK0 ENST00000512820.5 [Q9UPQ0-4] G5EA03 Q6NVB9 |