LDB2 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
endothelial cell	50 studies	56% ± 21%	Explore
endothelial cell of lymphatic vessel	22 studies	53% ± 21%	Explore
fibroblast	20 studies	32% ± 16%	Explore
pericyte	18 studies	31% ± 15%	Explore
capillary endothelial cell	16 studies	51% ± 17%	Explore
endothelial cell of artery	15 studies	57% ± 23%	Explore
vein endothelial cell	15 studies	56% ± 23%	Explore
glutamatergic neuron	11 studies	69% ± 27%	Explore
endothelial cell of vascular tree	11 studies	53% ± 25%	Explore
connective tissue cell	7 studies	30% ± 10%	Explore
smooth muscle cell	6 studies	38% ± 12%	Explore
neuron	6 studies	43% ± 20%	Explore
natural killer cell	6 studies	22% ± 5%	Explore
astrocyte	6 studies	34% ± 17%	Explore
GABAergic neuron	5 studies	45% ± 11%	Explore
oligodendrocyte precursor cell	5 studies	30% ± 9%	Explore
endothelial cell of sinusoid	4 studies	66% ± 19%	Explore
glomerular endothelial cell	4 studies	76% ± 7%	Explore
microglial cell	4 studies	42% ± 24%	Explore
CD16-negative, CD56-bright natural killer cell, human	4 studies	40% ± 11%	Explore
mast cell	4 studies	29% ± 15%	Explore
retinal bipolar neuron	3 studies	35% ± 20%	Explore
endocardial cell	3 studies	80% ± 18%	Explore
GABAergic amacrine cell	3 studies	40% ± 7%	Explore
myofibroblast cell	3 studies	18% ± 3%	Explore
interneuron	3 studies	42% ± 18%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	13 studies	41% ± 23%	Explore
lung	5 studies	19% ± 4%	Explore
heart	5 studies	23% ± 6%	Explore
adipose	3 studies	39% ± 15%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	3835.92	653 / 653	93%	15.35	561 / 605
adrenal gland	98%	1634.94	252 / 258	93%	15.45	215 / 230
breast	100%	6009.50	459 / 459	89%	8.37	999 / 1118
prostate	98%	2220.27	240 / 245	88%	7.05	440 / 502
lung	100%	6819.32	578 / 578	81%	6.61	933 / 1155
kidney	100%	2808.74	89 / 89	77%	28.99	695 / 901
brain	64%	1839.96	1699 / 2642	95%	12.16	667 / 705
ovary	98%	1883.43	177 / 180	58%	3.39	249 / 430
bladder	100%	1971.71	21 / 21	56%	3.62	282 / 504
uterus	99%	6733.88	169 / 170	52%	5.66	237 / 459
esophagus	87%	1479.97	1264 / 1445	61%	3.61	112 / 183
intestine	89%	1403.88	860 / 966	54%	3.34	282 / 527
stomach	79%	995.13	282 / 359	61%	4.10	174 / 286
liver	53%	538.56	120 / 226	71%	4.82	289 / 406
pancreas	24%	206.32	80 / 328	93%	10.44	166 / 178
skin	57%	713.98	1033 / 1809	50%	4.08	234 / 472
adipose	100%	6217.48	1204 / 1204	0%	0	0 / 0
spleen	100%	5572.33	241 / 241	0%	0	0 / 0
heart	99%	2194.85	852 / 861	0%	0	0 / 0
blood vessel	82%	1459.31	1097 / 1335	0%	0	0 / 0
muscle	60%	584.81	480 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	46%	2.74	37 / 80
tonsil	0%	0	0 / 0	38%	1.63	17 / 45
lymph node	0%	0	0 / 0	17%	0.77	5 / 29
peripheral blood	0%	1.36	2 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1