Tissue | GTEx Coverage  | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| kidney | 100% | 21825.06 | 89 / 89 | 99% | 76.79 | 889 / 901 |
| bladder | 100% | 19349.95 | 21 / 21 | 97% | 37.11 | 489 / 504 |
| thymus | 100% | 16797.53 | 650 / 653 | 97% | 48.58 | 587 / 605 |
| intestine | 100% | 25853.36 | 965 / 966 | 96% | 35.89 | 508 / 527 |
| breast | 100% | 27380.78 | 457 / 459 | 96% | 37.60 | 1071 / 1118 |
| lung | 100% | 36933.61 | 578 / 578 | 94% | 32.48 | 1091 / 1155 |
| stomach | 97% | 14945.01 | 348 / 359 | 97% | 33.76 | 278 / 286 |
| skin | 99% | 30165.58 | 1782 / 1809 | 93% | 59.39 | 441 / 472 |
| pancreas | 89% | 10282.78 | 291 / 328 | 98% | 59.59 | 175 / 178 |
| uterus | 99% | 21494.49 | 168 / 170 | 86% | 36.35 | 393 / 459 |
| esophagus | 87% | 18138.91 | 1255 / 1445 | 97% | 38.76 | 177 / 183 |
| adrenal gland | 91% | 7942.68 | 234 / 258 | 76% | 23.79 | 175 / 230 |
| prostate | 76% | 6729.12 | 185 / 245 | 60% | 9.83 | 302 / 502 |
| ovary | 76% | 9572.79 | 136 / 180 | 41% | 7.50 | 177 / 430 |
| ureter | 0% | 0 | 0 / 0 | 100% | 8.55 | 1 / 1 |
| adipose | 100% | 35738.90 | 1200 / 1204 | 0% | 0 | 0 / 0 |
| heart | 97% | 12910.01 | 838 / 861 | 0% | 0 | 0 / 0 |
| spleen | 96% | 17036.85 | 232 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 91% | 23.94 | 41 / 45 |
| blood vessel | 86% | 12749.39 | 1145 / 1335 | 0% | 0 | 0 / 0 |
| liver | 19% | 1265.33 | 44 / 226 | 51% | 14.65 | 206 / 406 |
| brain | 16% | 1138.01 | 424 / 2642 | 35% | 9.14 | 248 / 705 |
| lymph node | 0% | 0 | 0 / 0 | 45% | 6.87 | 13 / 29 |
| muscle | 38% | 2831.42 | 305 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 8% | 0.72 | 6 / 80 |
| peripheral blood | 0% | 19.98 | 3 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0042476 | Biological process | odontogenesis |
| GO_0031175 | Biological process | neuron projection development |
| GO_0021812 | Biological process | neuronal-glial interaction involved in cerebral cortex radial glia guided migration |
| GO_0051149 | Biological process | positive regulation of muscle cell differentiation |
| GO_0035987 | Biological process | endodermal cell differentiation |
| GO_2001046 | Biological process | positive regulation of integrin-mediated signaling pathway |
| GO_0007155 | Biological process | cell adhesion |
| GO_0045785 | Biological process | positive regulation of cell adhesion |
| GO_0050679 | Biological process | positive regulation of epithelial cell proliferation |
| GO_0034446 | Biological process | substrate adhesion-dependent cell spreading |
| GO_0030335 | Biological process | positive regulation of cell migration |
| GO_0110011 | Biological process | regulation of basement membrane organization |
| GO_0005615 | Cellular component | extracellular space |
| GO_0043257 | Cellular component | laminin-8 complex |
| GO_0005576 | Cellular component | extracellular region |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0062023 | Cellular component | collagen-containing extracellular matrix |
| GO_0005606 | Cellular component | laminin-1 complex |
| GO_0005607 | Cellular component | laminin-2 complex |
| GO_0005788 | Cellular component | endoplasmic reticulum lumen |
| GO_0043259 | Cellular component | laminin-10 complex |
| GO_0098637 | Cellular component | protein complex involved in cell-matrix adhesion |
| GO_0005604 | Cellular component | basement membrane |
| GO_0005201 | Molecular function | extracellular matrix structural constituent |
| GO_0005198 | Molecular function | structural molecule activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | LAMB1 |
| Protein name | Laminin, beta 1 (LAMB1) Laminin subunit beta 1 Alternative protein LAMB1 Laminin subunit beta-1 (Laminin B1 chain) (Laminin-1 subunit beta) (Laminin-10 subunit beta) (Laminin-12 subunit beta) (Laminin-2 subunit beta) (Laminin-6 subunit beta) (Laminin-8 subunit beta) LAMB1 protein |
| Synonyms | |
| Description | FUNCTION: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Involved in the organization of the laminar architecture of cerebral cortex. It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons. Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface. . |
| Accessions | ENST00000679200.1 ENST00000679244.1 ENST00000677101.1 ENST00000393559.2 A0A7I2V2R2 A0A7I2V378 A0A7I2V5R0 Q8TAS6 ENST00000677793.1 A0A7I2V3I5 ENST00000678704.1 ENST00000677588.1 ENST00000678346.1 ENST00000677801.1 A0A7I2V3J7 ENST00000676574.1 G3XAI2 A0A7I2V5X5 ENST00000222399.11 C9J296 ENST00000439976.6 L8E7Q3 A0A7I2V4J9 ENST00000678892.1 P07942 A0A7I2V2T9 ENST00000676920.1 ENST00000676777.1 A0A7I2V682 Q75MC8 A0A7I2V407 ENST00000393560.5 ENST00000678698.1 A0A7I2V5T9 E9PCS6 E7EPA6 ENST00000393561.6 ENST00000677144.1 A0A7I2V2J0 |
