KLF11 | OmnibusX

Name	Number of supported studies	Average coverage
endothelial cell	6 studies	21% ± 3%	Explore
non-classical monocyte	4 studies	29% ± 13%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of KLF11 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	100%	1735.40	89 / 89	98%	28.89	884 / 901
breast	100%	3902.86	459 / 459	97%	18.50	1082 / 1118
pancreas	99%	2124.27	326 / 328	97%	15.07	173 / 178
lung	100%	2585.89	576 / 578	97%	18.19	1119 / 1155
intestine	99%	2267.72	956 / 966	96%	13.08	508 / 527
stomach	100%	1702.90	359 / 359	94%	13.91	270 / 286
ovary	100%	2251.21	180 / 180	94%	16.28	404 / 430
uterus	100%	2261.77	170 / 170	92%	18.48	423 / 459
esophagus	96%	1705.57	1380 / 1445	96%	16.08	176 / 183
thymus	100%	1729.32	651 / 653	88%	13.96	534 / 605
bladder	100%	2098.48	21 / 21	88%	12.95	443 / 504
prostate	95%	1065.13	232 / 245	90%	12.16	454 / 502
liver	93%	1638.01	211 / 226	90%	16.46	367 / 406
skin	86%	2872.82	1554 / 1809	92%	14.30	433 / 472
adrenal gland	99%	1714.17	255 / 258	77%	9.15	176 / 230
adipose	100%	4508.43	1204 / 1204	0%	0	0 / 0
spleen	100%	1753.54	241 / 241	0%	0	0 / 0
blood vessel	99%	2517.90	1327 / 1335	0%	0	0 / 0
muscle	95%	1141.27	765 / 803	0%	0	0 / 0
heart	95%	1235.48	816 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	93%	23.40	42 / 45
brain	29%	283.37	758 / 2642	62%	4.25	435 / 705
eye	0%	0	0 / 0	78%	8.09	62 / 80
lymph node	0%	0	0 / 0	55%	4.29	16 / 29
peripheral blood	33%	261.31	306 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_1901653	Biological process	cellular response to peptide
GO_0008285	Biological process	negative regulation of cell population proliferation
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_2000045	Biological process	regulation of G1/S transition of mitotic cell cycle
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0006915	Biological process	apoptotic process
GO_0043065	Biological process	positive regulation of apoptotic process
GO_0005654	Cellular component	nucleoplasm
GO_0005925	Cellular component	focal adhesion
GO_0016604	Cellular component	nuclear body
GO_0005829	Cellular component	cytosol
GO_0000785	Cellular component	chromatin
GO_0005634	Cellular component	nucleus
GO_0000978	Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_0000976	Molecular function	transcription cis-regulatory region binding
GO_1990837	Molecular function	sequence-specific double-stranded DNA binding
GO_0003700	Molecular function	DNA-binding transcription factor activity
GO_0046872	Molecular function	metal ion binding
GO_0005515	Molecular function	protein binding

Gene name	KLF11
Protein name	Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2) Alternative protein KLF11 KLF transcription factor 11
Synonyms	FKLF TIEG2
Description	FUNCTION: Transcription factor . Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth . Represses transcription of SMAD7 which enhances TGF-beta signaling (By similarity). Induces apoptosis (By similarity). .
Accessions	ENST00000401510.5 E7EX78 ENST00000440320.5 L8EA48 O14901 ENST00000448523.5 ENST00000535335.1 [O14901-2] B5MCC4 ENST00000540845.5 [O14901-2] C9JM94 ENST00000305883.6 [O14901-1]

KLF11 report