KIF13A report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0035459Biological processvesicle cargo loading
GO_0072383Biological processplus-end-directed vesicle transport along microtubule
GO_0006886Biological processintracellular protein transport
GO_0051301Biological processcell division
GO_0032438Biological processmelanosome organization
GO_0008333Biological processendosome to lysosome transport
GO_0007018Biological processmicrotubule-based movement
GO_0043001Biological processGolgi to plasma membrane protein transport
GO_0032465Biological processregulation of cytokinesis
GO_0030705Biological processcytoskeleton-dependent intracellular transport
GO_0030496Cellular componentmidbody
GO_0005874Cellular componentmicrotubule
GO_0005813Cellular componentcentrosome
GO_0005871Cellular componentkinesin complex
GO_0032588Cellular componenttrans-Golgi network membrane
GO_0000139Cellular componentGolgi membrane
GO_0010008Cellular componentendosome membrane
GO_0003777Molecular functionmicrotubule motor activity
GO_0008017Molecular functionmicrotubule binding
GO_0005524Molecular functionATP binding
GO_0005515Molecular functionprotein binding
GO_0016887Molecular functionATP hydrolysis activity

IV. Literature review

[source]
Gene nameKIF13A
Protein nameKinesin family member 13A
Kinesin-like protein KIF13A (Kinesin-like protein RBKIN)
SynonymsRBKIN
DescriptionFUNCTION: Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenesis and cytokinesis. Mediates the transport of M6PR-containing vesicles from trans-Golgi network to the plasma membrane via direct interaction with the AP-1 complex. During melanosome maturation, required for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes by creating peripheral recycling endosomal subdomains in melanocytes. Also required for the abcission step in cytokinesis: mediates translocation of ZFYVE26, and possibly TTC19, to the midbody during cytokinesis. .

AccessionsENST00000378814.9 [Q9H1H9-3]
ENST00000259711.11 [Q9H1H9-1]
Q9H1H9
ENST00000502297.5
H0Y925
H0Y307
ENST00000378843.6 [Q9H1H9-4]
ENST00000506044.1
ENST00000502704.2 [Q9H1H9-5]
ENST00000378826.6 [Q9H1H9-2]
ENST00000636847.1
ENST00000358380.10
H0Y9Z7
A0A1B0GUA8