Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 13 studies | 26% ± 10% | |
| astrocyte | 11 studies | 28% ± 12% | |
| microglial cell | 10 studies | 27% ± 9% | |
| oligodendrocyte precursor cell | 9 studies | 25% ± 11% | |
| oligodendrocyte | 9 studies | 25% ± 7% | |
| macrophage | 8 studies | 30% ± 11% | |
| myeloid cell | 8 studies | 22% ± 6% | |
| epithelial cell | 7 studies | 29% ± 12% | |
| glutamatergic neuron | 6 studies | 43% ± 22% | |
| interneuron | 6 studies | 32% ± 21% | |
| adipocyte | 6 studies | 26% ± 4% | |
| dendritic cell | 6 studies | 22% ± 5% | |
| ciliated cell | 6 studies | 27% ± 9% | |
| GABAergic neuron | 6 studies | 37% ± 17% | |
| mast cell | 5 studies | 22% ± 5% | |
| basal cell | 5 studies | 25% ± 12% | |
| endothelial cell of lymphatic vessel | 5 studies | 25% ± 7% | |
| fibroblast | 5 studies | 24% ± 7% | |
| type I pneumocyte | 5 studies | 20% ± 6% | |
| retinal pigment epithelial cell | 4 studies | 28% ± 10% | |
| monocyte | 4 studies | 29% ± 6% | |
| pericyte | 4 studies | 23% ± 8% | |
| smooth muscle cell | 4 studies | 20% ± 1% | |
| type II pneumocyte | 4 studies | 19% ± 5% | |
| goblet cell | 4 studies | 33% ± 21% | |
| classical monocyte | 3 studies | 24% ± 4% | |
| hematopoietic precursor cell | 3 studies | 20% ± 6% | |
| retinal rod cell | 3 studies | 19% ± 4% | |
| B cell | 3 studies | 22% ± 4% | |
| T cell | 3 studies | 18% ± 1% | |
| alveolar macrophage | 3 studies | 23% ± 8% | |
| club cell | 3 studies | 22% ± 6% | |
| lymphocyte | 3 studies | 27% ± 6% | |
| transit amplifying cell | 3 studies | 30% ± 15% | |
| neuron | 3 studies | 31% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 6022.74 | 1445 / 1445 | 100% | 47.13 | 183 / 183 |
| intestine | 100% | 6695.80 | 966 / 966 | 100% | 45.14 | 526 / 527 |
| prostate | 100% | 5629.00 | 245 / 245 | 100% | 48.79 | 501 / 502 |
| brain | 100% | 4231.16 | 2636 / 2642 | 100% | 63.41 | 705 / 705 |
| breast | 100% | 6572.82 | 459 / 459 | 100% | 58.00 | 1115 / 1118 |
| stomach | 100% | 4815.49 | 359 / 359 | 100% | 44.19 | 285 / 286 |
| ovary | 100% | 7592.21 | 180 / 180 | 100% | 37.66 | 428 / 430 |
| lung | 100% | 5367.38 | 577 / 578 | 100% | 40.46 | 1151 / 1155 |
| thymus | 100% | 6162.89 | 653 / 653 | 99% | 56.23 | 601 / 605 |
| bladder | 100% | 7079.67 | 21 / 21 | 99% | 36.51 | 499 / 504 |
| skin | 100% | 6631.72 | 1809 / 1809 | 99% | 42.52 | 465 / 472 |
| uterus | 100% | 6850.04 | 170 / 170 | 98% | 37.93 | 452 / 459 |
| kidney | 100% | 3666.19 | 89 / 89 | 98% | 43.54 | 887 / 901 |
| pancreas | 99% | 3068.03 | 325 / 328 | 99% | 40.00 | 176 / 178 |
| adrenal gland | 100% | 5237.26 | 258 / 258 | 98% | 33.48 | 225 / 230 |
| liver | 100% | 1749.68 | 225 / 226 | 85% | 18.80 | 346 / 406 |
| adipose | 100% | 5884.84 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 6759.51 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 36.76 | 29 / 29 |
| muscle | 100% | 7242.07 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 6697.46 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 45.75 | 45 / 45 |
| eye | 0% | 0 | 0 / 0 | 99% | 36.15 | 79 / 80 |
| heart | 98% | 3579.06 | 841 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 97% | 5418.17 | 905 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0098869 | Biological process | cellular oxidant detoxification |
| GO_0006338 | Biological process | chromatin remodeling |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0000118 | Cellular component | histone deacetylase complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0000785 | Cellular component | chromatin |
| GO_0031490 | Molecular function | chromatin DNA binding |
| GO_0140683 | Molecular function | histone H3K9me/H3K9me2 demethylase activity |
| GO_0032454 | Molecular function | histone H3K9 demethylase activity |
| GO_0016209 | Molecular function | antioxidant activity |
| GO_0003712 | Molecular function | transcription coregulator activity |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | KDM3B |
| Protein name | Lysine demethylase 3B Lysine-specific demethylase 3B (EC 1.14.11.65) (JmjC domain-containing histone demethylation protein 2B) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA) ([histone H3]-dimethyl-L-lysine(9) demethylase 3B) |
| Synonyms | C5orf7 KIAA1082 JMJD1B JHDM2B |
| Description | FUNCTION: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. . |
| Accessions | ENST00000314358.10 [Q7LBC6-1] H0Y946 H0Y9V5 ENST00000510866.5 ENST00000507996.5 Q7LBC6 |