KDM3B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0098869Biological processcellular oxidant detoxification
GO_0006338Biological processchromatin remodeling
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000118Cellular componenthistone deacetylase complex
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0031490Molecular functionchromatin DNA binding
GO_0140683Molecular functionhistone H3K9me/H3K9me2 demethylase activity
GO_0032454Molecular functionhistone H3K9 demethylase activity
GO_0016209Molecular functionantioxidant activity
GO_0003712Molecular functiontranscription coregulator activity
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameKDM3B
Protein nameLysine demethylase 3B
Lysine-specific demethylase 3B (EC 1.14.11.65) (JmjC domain-containing histone demethylation protein 2B) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA) ([histone H3]-dimethyl-L-lysine(9) demethylase 3B)
SynonymsC5orf7
KIAA1082
JMJD1B
JHDM2B
DescriptionFUNCTION: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. .

AccessionsENST00000314358.10 [Q7LBC6-1]
H0Y946
H0Y9V5
ENST00000510866.5
ENST00000507996.5
Q7LBC6