INTS10 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
ciliated cell	15 studies	30% ± 14%	Explore
astrocyte	11 studies	32% ± 16%	Explore
oligodendrocyte precursor cell	11 studies	34% ± 16%	Explore
endothelial cell	10 studies	27% ± 7%	Explore
microglial cell	10 studies	26% ± 9%	Explore
glutamatergic neuron	9 studies	38% ± 26%	Explore
fibroblast	9 studies	23% ± 6%	Explore
adipocyte	9 studies	23% ± 5%	Explore
macrophage	9 studies	22% ± 8%	Explore
B cell	8 studies	19% ± 4%	Explore
plasmacytoid dendritic cell	8 studies	25% ± 5%	Explore
GABAergic neuron	6 studies	38% ± 19%	Explore
epithelial cell	6 studies	34% ± 12%	Explore
oligodendrocyte	6 studies	31% ± 6%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	20% ± 2%	Explore
neuron	5 studies	33% ± 15%	Explore
retina horizontal cell	5 studies	28% ± 4%	Explore
retinal rod cell	5 studies	23% ± 2%	Explore
basal cell	5 studies	26% ± 8%	Explore
naive B cell	5 studies	18% ± 3%	Explore
CD16-positive, CD56-dim natural killer cell, human	4 studies	16% ± 1%	Explore
CD4-positive, alpha-beta T cell	4 studies	21% ± 3%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	19% ± 4%	Explore
precursor B cell	4 studies	25% ± 6%	Explore
myeloid cell	4 studies	17% ± 3%	Explore
amacrine cell	4 studies	24% ± 5%	Explore
type I pneumocyte	4 studies	18% ± 3%	Explore
dendritic cell	4 studies	29% ± 15%	Explore
natural killer cell	4 studies	18% ± 2%	Explore
interneuron	4 studies	39% ± 20%	Explore
gamma-delta T cell	4 studies	21% ± 8%	Explore
conventional dendritic cell	3 studies	29% ± 10%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	18% ± 2%	Explore
non-classical monocyte	3 studies	25% ± 6%	Explore
immature B cell	3 studies	19% ± 2%	Explore
retinal cone cell	3 studies	27% ± 7%	Explore
rod bipolar cell	3 studies	16% ± 0%	Explore
type II pneumocyte	3 studies	21% ± 4%	Explore
abnormal cell	3 studies	29% ± 8%	Explore
club cell	3 studies	20% ± 2%	Explore
pericyte	3 studies	17% ± 1%	Explore
T follicular helper cell	3 studies	16% ± 1%	Explore
Schwann cell	3 studies	26% ± 8%	Explore
transit amplifying cell	3 studies	26% ± 8%	Explore
goblet cell	3 studies	19% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	14 studies	30% ± 19%	Explore
eye	6 studies	22% ± 4%	Explore
peripheral blood	4 studies	23% ± 6%	Explore
liver	4 studies	25% ± 9%	Explore
lung	3 studies	24% ± 3%	Explore
intestine	3 studies	20% ± 4%	Explore
adipose	3 studies	17% ± 1%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2824.84	1445 / 1445	100%	25.51	183 / 183
intestine	100%	2924.46	966 / 966	100%	30.44	527 / 527
lung	100%	3246.12	578 / 578	100%	27.15	1155 / 1155
ovary	100%	2576.64	180 / 180	100%	18.14	430 / 430
pancreas	100%	3903.45	328 / 328	100%	23.80	178 / 178
prostate	100%	3692.94	245 / 245	100%	43.29	502 / 502
stomach	100%	2603.70	359 / 359	100%	28.54	286 / 286
thymus	100%	4740.08	653 / 653	100%	40.27	605 / 605
uterus	100%	2766.98	170 / 170	100%	30.56	459 / 459
brain	100%	2671.82	2640 / 2642	100%	34.73	705 / 705
breast	100%	3315.01	459 / 459	100%	25.69	1117 / 1118
bladder	100%	3240.52	21 / 21	100%	25.54	503 / 504
adrenal gland	100%	3018.11	258 / 258	100%	20.99	229 / 230
kidney	100%	2855.48	89 / 89	99%	21.34	896 / 901
liver	100%	3078.32	226 / 226	99%	15.27	401 / 406
skin	100%	3468.62	1809 / 1809	97%	30.51	459 / 472
adipose	100%	3355.83	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	23.26	29 / 29
spleen	100%	2809.93	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	35.98	45 / 45
ureter	0%	0	0 / 0	100%	7.41	1 / 1
blood vessel	100%	2850.83	1334 / 1335	0%	0	0 / 0
muscle	100%	1647.71	799 / 803	0%	0	0 / 0
heart	98%	1704.96	841 / 861	0%	0	0 / 0
peripheral blood	91%	1427.36	841 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	84%	11.88	67 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0034243	Biological process	regulation of transcription elongation by RNA polymerase II
GO_0016180	Biological process	snRNA processing
GO_0032039	Cellular component	integrator complex
GO_0005654	Cellular component	nucleoplasm
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	INTS10
Protein name	Integrator complex subunit 10 (Int10) Integrator complex subunit 10
Synonyms	C8orf35
Description	FUNCTION: Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex . .
Accessions	E5RJN5 H0YBW3 ENST00000523846.1 ENST00000523869.1 H0YAU7 ENST00000521357.5 ENST00000520670.1 H0YB48 H0YC09 E5RHN1 ENST00000522114.5 ENST00000518424.1 H0YB36 ENST00000518799.1 H0YBH6 Q9NVR2 ENST00000521008.1 ENST00000520827.1 ENST00000397977.8 H0YAY7 ENST00000523772.1 H0YBB0

INTS10 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review