HIVEP2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	23 studies	34% ± 14%	Explore
astrocyte	15 studies	32% ± 15%	Explore
fibroblast	14 studies	32% ± 12%	Explore
glutamatergic neuron	13 studies	59% ± 24%	Explore
pericyte	11 studies	32% ± 13%	Explore
GABAergic neuron	10 studies	49% ± 28%	Explore
oligodendrocyte precursor cell	10 studies	35% ± 12%	Explore
oligodendrocyte	10 studies	30% ± 10%	Explore
smooth muscle cell	9 studies	25% ± 6%	Explore
macrophage	8 studies	28% ± 15%	Explore
adipocyte	7 studies	24% ± 5%	Explore
neuron	6 studies	36% ± 15%	Explore
interneuron	6 studies	52% ± 28%	Explore
microglial cell	6 studies	24% ± 7%	Explore
epithelial cell	5 studies	37% ± 19%	Explore
T cell	5 studies	27% ± 10%	Explore
endothelial cell of lymphatic vessel	5 studies	38% ± 9%	Explore
club cell	5 studies	24% ± 8%	Explore
squamous epithelial cell	4 studies	28% ± 13%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	4 studies	25% ± 6%	Explore
granule cell	4 studies	46% ± 4%	Explore
B cell	4 studies	30% ± 8%	Explore
CD4-positive, alpha-beta T cell	4 studies	25% ± 7%	Explore
mesothelial cell	4 studies	21% ± 7%	Explore
vein endothelial cell	4 studies	29% ± 12%	Explore
amacrine cell	4 studies	26% ± 7%	Explore
retinal cone cell	4 studies	36% ± 15%	Explore
capillary endothelial cell	4 studies	24% ± 3%	Explore
regulatory T cell	4 studies	25% ± 8%	Explore
type I pneumocyte	4 studies	26% ± 4%	Explore
type II pneumocyte	4 studies	27% ± 4%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	20% ± 5%	Explore
GABAergic interneuron	3 studies	52% ± 6%	Explore
progenitor cell	3 studies	31% ± 2%	Explore
CD8-positive, alpha-beta T cell	3 studies	23% ± 5%	Explore
cardiac muscle cell	3 studies	25% ± 5%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	20% ± 3%	Explore
mucosal invariant T cell	3 studies	23% ± 5%	Explore
ciliated cell	3 studies	30% ± 7%	Explore
endothelial cell of artery	3 studies	22% ± 3%	Explore
endothelial cell of vascular tree	3 studies	29% ± 17%	Explore
cholangiocyte	3 studies	49% ± 19%	Explore
hepatocyte	3 studies	45% ± 31%	Explore
luminal cell of prostate epithelium	3 studies	17% ± 1%	Explore
ependymal cell	3 studies	38% ± 16%	Explore
myofibroblast cell	3 studies	24% ± 12%	Explore
natural killer cell	3 studies	21% ± 3%	Explore
lymphocyte	3 studies	47% ± 15%	Explore
mural cell	3 studies	42% ± 5%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	17 studies	41% ± 21%	Explore
lung	4 studies	22% ± 5%	Explore
heart	3 studies	23% ± 5%	Explore
adipose	3 studies	21% ± 4%	Explore
kidney	3 studies	20% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2438.44	1444 / 1445	100%	23.60	183 / 183
thymus	100%	3196.46	652 / 653	99%	14.65	599 / 605
pancreas	100%	1687.05	327 / 328	99%	14.89	176 / 178
lung	100%	3510.56	576 / 578	99%	14.43	1140 / 1155
ovary	100%	4615.82	180 / 180	98%	16.89	421 / 430
brain	99%	4673.56	2626 / 2642	98%	16.03	693 / 705
prostate	100%	2413.52	244 / 245	98%	10.79	490 / 502
uterus	100%	2208.02	170 / 170	97%	12.19	444 / 459
kidney	100%	1975.15	89 / 89	96%	13.72	868 / 901
bladder	100%	2656.76	21 / 21	96%	11.22	484 / 504
breast	100%	2998.32	459 / 459	95%	12.71	1067 / 1118
intestine	100%	2315.25	964 / 966	95%	9.77	503 / 527
stomach	97%	1627.08	350 / 359	97%	11.87	277 / 286
skin	100%	3389.83	1808 / 1809	91%	10.58	428 / 472
adrenal gland	100%	2410.56	258 / 258	87%	8.30	199 / 230
liver	74%	843.02	167 / 226	48%	3.00	195 / 406
adipose	100%	3469.75	1204 / 1204	0%	0	0 / 0
blood vessel	100%	4500.92	1335 / 1335	0%	0	0 / 0
muscle	100%	3861.74	803 / 803	0%	0	0 / 0
spleen	100%	2317.60	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	4.08	1 / 1
tonsil	0%	0	0 / 0	98%	15.44	44 / 45
heart	96%	2060.67	825 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	86%	12.30	25 / 29
eye	0%	0	0 / 0	73%	4.82	58 / 80
peripheral blood	64%	1349.18	594 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0005654	Cellular component	nucleoplasm
GO_0005634	Cellular component	nucleus
GO_0003677	Molecular function	DNA binding
GO_0000978	Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0005515	Molecular function	protein binding
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_0046872	Molecular function	metal ion binding

IV. Literature review

[source]

Gene name	HIVEP2
Protein name	HIVEP zinc finger 2 Transcription factor HIVEP2 (Human immunodeficiency virus type I enhancer-binding protein 2) (HIV-EP2) (MHC-binding protein 2) (MBP-2)
Synonyms
Description	FUNCTION: This protein specifically binds to the DNA sequence 5'-GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, somatostatin receptor II, and interferon-beta genes. It may act in T-cell activation.
Accessions	ENST00000012134.7 P31629 ENST00000703920.1 A0A994J411 A0A994J481 ENST00000367603.8 A0A994J6P4 ENST00000703917.1 A0A994J742 ENST00000367604.6 ENST00000703918.1 ENST00000703916.1 ENST00000474532.2 ENST00000703919.1

HIVEP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review