HIBADH | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	17 studies	24% ± 7%	Explore
endothelial cell	12 studies	26% ± 12%	Explore
astrocyte	12 studies	37% ± 13%	Explore
oligodendrocyte precursor cell	11 studies	34% ± 15%	Explore
macrophage	10 studies	26% ± 7%	Explore
ciliated cell	10 studies	26% ± 6%	Explore
pericyte	9 studies	27% ± 10%	Explore
adipocyte	9 studies	33% ± 8%	Explore
oligodendrocyte	9 studies	29% ± 8%	Explore
epithelial cell	8 studies	29% ± 13%	Explore
GABAergic neuron	7 studies	36% ± 20%	Explore
epithelial cell of proximal tubule	7 studies	30% ± 9%	Explore
kidney loop of Henle epithelial cell	7 studies	40% ± 12%	Explore
renal alpha-intercalated cell	7 studies	33% ± 10%	Explore
glutamatergic neuron	6 studies	40% ± 24%	Explore
microglial cell	6 studies	22% ± 4%	Explore
smooth muscle cell	6 studies	21% ± 6%	Explore
retina horizontal cell	5 studies	36% ± 13%	Explore
cardiac muscle cell	5 studies	23% ± 4%	Explore
Mueller cell	5 studies	25% ± 7%	Explore
hepatocyte	5 studies	46% ± 17%	Explore
abnormal cell	4 studies	27% ± 12%	Explore
amacrine cell	4 studies	33% ± 21%	Explore
retinal bipolar neuron	4 studies	21% ± 0%	Explore
retinal pigment epithelial cell	4 studies	42% ± 16%	Explore
retinal rod cell	4 studies	19% ± 2%	Explore
basal cell	4 studies	42% ± 5%	Explore
endothelial cell of lymphatic vessel	4 studies	23% ± 9%	Explore
interneuron	4 studies	43% ± 19%	Explore
retinal ganglion cell	3 studies	33% ± 9%	Explore
placental villous trophoblast	3 studies	30% ± 9%	Explore
myofibroblast cell	3 studies	23% ± 6%	Explore
retinal cone cell	3 studies	19% ± 2%	Explore
mesothelial cell	3 studies	26% ± 7%	Explore
GABAergic amacrine cell	3 studies	27% ± 9%	Explore
glycinergic amacrine cell	3 studies	28% ± 6%	Explore
mast cell	3 studies	23% ± 5%	Explore
monocyte	3 studies	22% ± 2%	Explore
connective tissue cell	3 studies	23% ± 3%	Explore
myeloid cell	3 studies	16% ± 0%	Explore
intestinal crypt stem cell	3 studies	21% ± 4%	Explore
transit amplifying cell	3 studies	31% ± 19%	Explore
neuron	3 studies	30% ± 13%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	31% ± 2%	Explore
renal principal cell	3 studies	27% ± 10%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	8 studies	36% ± 17%	Explore
kidney	7 studies	22% ± 5%	Explore
eye	7 studies	25% ± 10%	Explore
lung	4 studies	24% ± 5%	Explore
heart	4 studies	18% ± 2%	Explore
liver	3 studies	36% ± 7%	Explore
adipose	3 studies	28% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
stomach	100%	2146.10	359 / 359	100%	82.40	286 / 286
breast	100%	3193.72	459 / 459	100%	94.99	1116 / 1118
prostate	100%	2704.52	245 / 245	100%	111.59	501 / 502
liver	100%	4943.09	226 / 226	100%	122.13	405 / 406
kidney	100%	5917.34	89 / 89	100%	168.54	897 / 901
ovary	100%	2332.26	180 / 180	100%	72.25	428 / 430
intestine	100%	2856.54	966 / 966	99%	89.82	523 / 527
thymus	100%	2920.57	653 / 653	99%	111.51	599 / 605
skin	100%	2169.10	1802 / 1809	99%	145.51	469 / 472
brain	99%	1451.18	2616 / 2642	100%	78.63	704 / 705
pancreas	99%	1202.55	326 / 328	99%	60.43	177 / 178
adrenal gland	100%	8147.57	258 / 258	99%	92.42	227 / 230
lung	99%	1491.61	571 / 578	100%	74.37	1153 / 1155
uterus	100%	3004.18	170 / 170	98%	64.52	449 / 459
bladder	100%	2802.33	21 / 21	98%	72.39	493 / 504
esophagus	99%	1964.56	1433 / 1445	96%	52.93	175 / 183
adipose	100%	3342.21	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	120.47	80 / 80
muscle	100%	4295.47	803 / 803	0%	0	0 / 0
spleen	100%	1285.49	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	27.27	1 / 1
blood vessel	100%	2223.99	1334 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	34.26	28 / 29
heart	96%	3129.11	826 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	91%	41.54	41 / 45
peripheral blood	26%	430.74	239 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0006574	Biological process	valine catabolic process
GO_0005759	Cellular component	mitochondrial matrix
GO_0005739	Cellular component	mitochondrion
GO_0050661	Molecular function	NADP binding
GO_0051287	Molecular function	NAD binding
GO_0008442	Molecular function	3-hydroxyisobutyrate dehydrogenase activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	HIBADH
Protein name	3-hydroxyisobutyrate dehydrogenase, mitochondrial (EC 1.1.1.31) 3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) (EC 1.1.1.31) 3-hydroxyisobutyrate dehydrogenase
Synonyms
Description
Accessions	ENST00000265395.7 H7BZL2 ENST00000428288.2 ENST00000425715.1 F8WET2 P31937

HIBADH report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review