GRHPR | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	16 studies	27% ± 11%	Explore
pericyte	13 studies	24% ± 9%	Explore
B cell	12 studies	25% ± 7%	Explore
endothelial cell	12 studies	25% ± 11%	Explore
smooth muscle cell	12 studies	25% ± 5%	Explore
connective tissue cell	11 studies	25% ± 7%	Explore
myofibroblast cell	8 studies	27% ± 4%	Explore
macrophage	8 studies	21% ± 8%	Explore
epithelial cell	8 studies	37% ± 19%	Explore
plasmacytoid dendritic cell	7 studies	25% ± 6%	Explore
classical monocyte	6 studies	25% ± 9%	Explore
epithelial cell of proximal tubule	6 studies	44% ± 7%	Explore
natural killer cell	6 studies	21% ± 3%	Explore
precursor B cell	6 studies	31% ± 8%	Explore
oligodendrocyte	6 studies	25% ± 8%	Explore
abnormal cell	6 studies	26% ± 6%	Explore
conventional dendritic cell	5 studies	33% ± 17%	Explore
mesothelial cell	5 studies	30% ± 16%	Explore
basal cell	5 studies	31% ± 17%	Explore
endothelial cell of lymphatic vessel	5 studies	22% ± 6%	Explore
astrocyte	5 studies	24% ± 12%	Explore
hepatocyte	5 studies	54% ± 23%	Explore
oligodendrocyte precursor cell	5 studies	27% ± 10%	Explore
non-classical monocyte	4 studies	29% ± 10%	Explore
CD16-negative, CD56-bright natural killer cell, human	4 studies	19% ± 1%	Explore
hematopoietic stem cell	4 studies	22% ± 4%	Explore
immature B cell	4 studies	25% ± 5%	Explore
ciliated cell	4 studies	33% ± 6%	Explore
endothelial cell of vascular tree	4 studies	17% ± 1%	Explore
neuron	4 studies	32% ± 10%	Explore
CD8-positive, alpha-beta T cell	4 studies	18% ± 2%	Explore
hematopoietic precursor cell	3 studies	33% ± 9%	Explore
memory B cell	3 studies	26% ± 12%	Explore
CD16-positive, CD56-dim natural killer cell, human	3 studies	17% ± 1%	Explore
CD4-positive, alpha-beta T cell	3 studies	21% ± 2%	Explore
kidney loop of Henle epithelial cell	3 studies	22% ± 4%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	23% ± 6%	Explore
neural crest cell	3 studies	22% ± 1%	Explore
plasma cell	3 studies	28% ± 8%	Explore
type I pneumocyte	3 studies	25% ± 5%	Explore
Mueller cell	3 studies	19% ± 3%	Explore
germinal center B cell	3 studies	39% ± 6%	Explore
dendritic cell	3 studies	42% ± 19%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	38% ± 23%	Explore
enteroendocrine cell	3 studies	27% ± 11%	Explore
goblet cell	3 studies	27% ± 7%	Explore
naive B cell	3 studies	25% ± 6%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	6 studies	28% ± 9%	Explore
peripheral blood	5 studies	23% ± 8%	Explore
kidney	5 studies	25% ± 10%	Explore
intestine	5 studies	24% ± 12%	Explore
liver	5 studies	33% ± 13%	Explore
brain	4 studies	25% ± 4%	Explore
eye	3 studies	21% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	16550.14	226 / 226	100%	110.04	406 / 406
ovary	100%	4802.37	180 / 180	100%	37.62	430 / 430
pancreas	100%	2531.75	328 / 328	100%	30.35	178 / 178
skin	100%	4762.96	1809 / 1809	100%	39.78	472 / 472
stomach	100%	3402.09	359 / 359	100%	32.03	286 / 286
brain	100%	3747.85	2640 / 2642	100%	57.35	705 / 705
breast	100%	4276.38	459 / 459	100%	39.99	1116 / 1118
prostate	100%	4222.51	245 / 245	100%	57.30	501 / 502
uterus	100%	4349.62	170 / 170	100%	38.57	458 / 459
kidney	100%	8042.84	89 / 89	100%	42.06	899 / 901
thymus	100%	3662.10	653 / 653	100%	38.03	603 / 605
lung	100%	3455.57	576 / 578	100%	30.49	1152 / 1155
intestine	100%	4013.69	966 / 966	99%	40.77	523 / 527
bladder	100%	3902.67	21 / 21	99%	35.31	498 / 504
adrenal gland	100%	9834.18	258 / 258	99%	38.78	227 / 230
esophagus	100%	4190.27	1445 / 1445	98%	21.34	180 / 183
adipose	100%	4228.56	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	55.08	80 / 80
lymph node	0%	0	0 / 0	100%	197.02	29 / 29
muscle	100%	4845.01	803 / 803	0%	0	0 / 0
spleen	100%	3185.04	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	35.96	45 / 45
ureter	0%	0	0 / 0	100%	21.85	1 / 1
blood vessel	100%	3865.37	1333 / 1335	0%	0	0 / 0
heart	98%	4261.29	847 / 861	0%	0	0 / 0
peripheral blood	88%	3051.68	814 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0043648	Biological process	dicarboxylic acid metabolic process
GO_0046487	Biological process	glyoxylate metabolic process
GO_0019752	Biological process	carboxylic acid metabolic process
GO_0070062	Cellular component	extracellular exosome
GO_1902494	Cellular component	catalytic complex
GO_0005829	Cellular component	cytosol
GO_0005782	Cellular component	peroxisomal matrix
GO_0005737	Cellular component	cytoplasm
GO_0042803	Molecular function	protein homodimerization activity
GO_0016618	Molecular function	hydroxypyruvate reductase [NAD(P)H] activity
GO_0051287	Molecular function	NAD binding
GO_0070402	Molecular function	NADPH binding
GO_0031406	Molecular function	carboxylic acid binding
GO_0030267	Molecular function	glyoxylate reductase (NADPH) activity
GO_0008465	Molecular function	hydroxypyruvate reductase (NADH) activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	GRHPR
Protein name	GRHPR protein Glyoxylate reductase/hydroxypyruvate reductase (EC 1.1.1.79) (EC 1.1.1.81) Glyoxylate and hydroxypyruvate reductase
Synonyms	GLXR MSTP035
Description	FUNCTION: Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate, oxidizes D-glycerate to hydroxypyruvate. .
Accessions	Q5M7Z5 Q9UBQ7 ENST00000494290.1 [Q9UBQ7-2] ENST00000318158.11 [Q9UBQ7-1] U3KQ56 ENST00000607784.1

GRHPR report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review