GFUS report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0010595Biological processpositive regulation of endothelial cell migration
GO_1904906Biological processpositive regulation of endothelial cell-matrix adhesion via fibronectin
GO_0042351Biological process'de novo' GDP-L-fucose biosynthetic process
GO_0019673Biological processGDP-mannose metabolic process
GO_0007159Biological processleukocyte cell-cell adhesion
GO_0070062Cellular componentextracellular exosome
GO_0005829Cellular componentcytosol
GO_0042356Molecular functionGDP-4-dehydro-D-rhamnose reductase activity
GO_0047918Molecular functionGDP-mannose 3,5-epimerase activity
GO_0050577Molecular functionGDP-L-fucose synthase activity
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0009055Molecular functionelectron transfer activity

IV. Literature review

[source]
Gene nameGFUS
Protein nameGDP-L-fucose synthase (EC 1.1.1.271) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase)
GDP-L-fucose synthase (EC 1.1.1.271) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase) (Protein FX) (Red cell NADP(H)-binding protein) (Short-chain dehydrogenase/reductase family 4E member 1)
GDP-L-fucose synthase
SynonymsSDR4E1
TSTA3
DescriptionFUNCTION: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. .

FUNCTION: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. .

AccessionsENST00000529064.5
E9PLH9
ENST00000533817.5
ENST00000632250.1
E9PKL9
Q13630
ENST00000612580.2
ENST00000633885.1
ENST00000425753.7
ENST00000526290.1
E9PP60
ENST00000633095.1
E9PP14
ENST00000633782.1
H0YE90
ENST00000529048.5
A0A0J9YX13
ENST00000524719.1
ENST00000527006.1
ENST00000632368.1
ENST00000633165.1
ENST00000530474.5
ENST00000632379.1
H0YCP7