Name | Number of supported studies | Average coverage | |
---|---|---|---|
peripheral blood | 3 studies | 19% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 6547.47 | 578 / 578 | 86% | 34.35 | 990 / 1155 |
breast | 100% | 2307.17 | 458 / 459 | 82% | 32.83 | 918 / 1118 |
esophagus | 98% | 1087.27 | 1409 / 1445 | 79% | 29.17 | 144 / 183 |
thymus | 100% | 1853.73 | 652 / 653 | 75% | 18.88 | 456 / 605 |
ovary | 100% | 1953.60 | 180 / 180 | 75% | 24.73 | 322 / 430 |
uterus | 99% | 1502.14 | 169 / 170 | 73% | 38.96 | 333 / 459 |
bladder | 95% | 1161.62 | 20 / 21 | 75% | 31.14 | 379 / 504 |
kidney | 100% | 1649.04 | 89 / 89 | 69% | 49.94 | 625 / 901 |
intestine | 98% | 1413.53 | 951 / 966 | 69% | 25.95 | 362 / 527 |
stomach | 89% | 856.03 | 321 / 359 | 75% | 44.21 | 215 / 286 |
prostate | 100% | 1624.78 | 245 / 245 | 60% | 11.64 | 300 / 502 |
liver | 93% | 757.65 | 211 / 226 | 55% | 11.45 | 222 / 406 |
adrenal gland | 95% | 888.08 | 245 / 258 | 51% | 9.22 | 117 / 230 |
skin | 48% | 341.83 | 867 / 1809 | 69% | 50.50 | 324 / 472 |
brain | 74% | 618.49 | 1956 / 2642 | 42% | 8.39 | 296 / 705 |
pancreas | 24% | 108.65 | 78 / 328 | 87% | 23.87 | 154 / 178 |
spleen | 100% | 3982.49 | 241 / 241 | 0% | 0 | 0 / 0 |
adipose | 100% | 3168.79 | 1203 / 1204 | 0% | 0 | 0 / 0 |
heart | 98% | 1179.50 | 847 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 97% | 92.19 | 28 / 29 |
tonsil | 0% | 0 | 0 / 0 | 91% | 66.42 | 41 / 45 |
muscle | 81% | 536.37 | 649 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 79% | 699.18 | 1054 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 78% | 1546.10 | 720 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 15% | 5.56 | 12 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0050830 | Biological process | defense response to Gram-positive bacterium |
GO_0042832 | Biological process | defense response to protozoan |
GO_0071346 | Biological process | cellular response to type II interferon |
GO_0000139 | Cellular component | Golgi membrane |
GO_0005829 | Cellular component | cytosol |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0005886 | Cellular component | plasma membrane |
GO_0031410 | Cellular component | cytoplasmic vesicle |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0005525 | Molecular function | GTP binding |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0005515 | Molecular function | protein binding |
GO_0003924 | Molecular function | GTPase activity |
Gene name | GBP4 |
Protein name | Guanylate-binding protein 4 (EC 3.6.5.-) (GTP-binding protein 4) (GBP-4) (Guanine nucleotide-binding protein 4) |
Synonyms | |
Description | FUNCTION: Interferon (IFN)-inducible GTPase that plays important roles in innate immunity against a diverse range of bacterial, viral and protozoan pathogens (By similarity). Negatively regulates the antiviral response by inhibiting activation of IRF7 transcription factor (By similarity). . |
Accessions | Q96PP9 ENST00000355754.7 |