Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 21 studies | 33% ± 13% | |
| astrocyte | 15 studies | 39% ± 17% | |
| oligodendrocyte precursor cell | 13 studies | 41% ± 16% | |
| microglial cell | 13 studies | 39% ± 12% | |
| glutamatergic neuron | 12 studies | 51% ± 27% | |
| oligodendrocyte | 11 studies | 33% ± 12% | |
| GABAergic neuron | 10 studies | 43% ± 23% | |
| macrophage | 10 studies | 33% ± 15% | |
| fibroblast | 10 studies | 29% ± 9% | |
| adipocyte | 9 studies | 30% ± 9% | |
| dendritic cell | 8 studies | 26% ± 10% | |
| mast cell | 8 studies | 29% ± 10% | |
| epithelial cell | 7 studies | 33% ± 19% | |
| pericyte | 7 studies | 31% ± 12% | |
| endothelial cell of lymphatic vessel | 7 studies | 41% ± 10% | |
| smooth muscle cell | 7 studies | 27% ± 6% | |
| ciliated cell | 7 studies | 36% ± 20% | |
| interneuron | 6 studies | 50% ± 22% | |
| T cell | 6 studies | 28% ± 8% | |
| neuron | 5 studies | 48% ± 18% | |
| B cell | 5 studies | 28% ± 6% | |
| CD8-positive, alpha-beta T cell | 5 studies | 23% ± 8% | |
| cardiac muscle cell | 5 studies | 31% ± 8% | |
| type I pneumocyte | 5 studies | 42% ± 7% | |
| type II pneumocyte | 5 studies | 36% ± 7% | |
| basal cell | 5 studies | 36% ± 22% | |
| granule cell | 4 studies | 39% ± 10% | |
| mesothelial cell | 4 studies | 34% ± 11% | |
| retinal cone cell | 4 studies | 33% ± 11% | |
| retinal rod cell | 4 studies | 31% ± 8% | |
| myeloid cell | 4 studies | 29% ± 5% | |
| club cell | 4 studies | 34% ± 10% | |
| monocyte | 4 studies | 29% ± 8% | |
| GABAergic interneuron | 3 studies | 36% ± 4% | |
| progenitor cell | 3 studies | 39% ± 11% | |
| plasma cell | 3 studies | 28% ± 6% | |
| CD4-positive, alpha-beta T cell | 3 studies | 23% ± 4% | |
| vein endothelial cell | 3 studies | 30% ± 19% | |
| Mueller cell | 3 studies | 28% ± 8% | |
| retinal ganglion cell | 3 studies | 44% ± 18% | |
| endothelial cell of vascular tree | 3 studies | 31% ± 14% | |
| hepatocyte | 3 studies | 46% ± 19% | |
| retinal pigment epithelial cell | 3 studies | 31% ± 15% | |
| ependymal cell | 3 studies | 49% ± 16% | |
| alveolar macrophage | 3 studies | 33% ± 7% | |
| capillary endothelial cell | 3 studies | 21% ± 4% | |
| natural killer cell | 3 studies | 25% ± 4% | |
| respiratory goblet cell | 3 studies | 39% ± 15% | |
| lymphocyte | 3 studies | 37% ± 8% | |
| transit amplifying cell | 3 studies | 42% ± 31% | |
| mucus secreting cell | 3 studies | 31% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 694.15 | 459 / 459 | 100% | 13.84 | 1118 / 1118 |
| esophagus | 100% | 541.06 | 1445 / 1445 | 100% | 7.28 | 183 / 183 |
| ovary | 100% | 465.02 | 180 / 180 | 100% | 10.03 | 430 / 430 |
| prostate | 100% | 503.29 | 245 / 245 | 100% | 10.74 | 502 / 502 |
| stomach | 100% | 497.64 | 359 / 359 | 100% | 8.95 | 286 / 286 |
| lung | 100% | 602.95 | 578 / 578 | 100% | 9.87 | 1154 / 1155 |
| kidney | 100% | 600.64 | 89 / 89 | 100% | 10.95 | 899 / 901 |
| thymus | 100% | 888.63 | 653 / 653 | 100% | 13.36 | 603 / 605 |
| uterus | 100% | 591.41 | 170 / 170 | 100% | 12.06 | 457 / 459 |
| liver | 100% | 363.84 | 225 / 226 | 100% | 10.91 | 406 / 406 |
| skin | 100% | 709.09 | 1808 / 1809 | 100% | 13.11 | 470 / 472 |
| intestine | 100% | 589.54 | 966 / 966 | 99% | 10.04 | 524 / 527 |
| bladder | 100% | 584.48 | 21 / 21 | 99% | 11.10 | 500 / 504 |
| pancreas | 99% | 329.39 | 325 / 328 | 100% | 9.05 | 178 / 178 |
| brain | 99% | 368.66 | 2616 / 2642 | 100% | 11.09 | 705 / 705 |
| adrenal gland | 100% | 751.41 | 258 / 258 | 98% | 10.61 | 226 / 230 |
| adipose | 100% | 601.51 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 12.55 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 20.74 | 29 / 29 |
| muscle | 100% | 620.46 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 636.78 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 11.69 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 13.33 | 1 / 1 |
| blood vessel | 100% | 584.43 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| heart | 97% | 604.41 | 838 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 91% | 374.45 | 846 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006432 | Biological process | phenylalanyl-tRNA aminoacylation |
| GO_0008033 | Biological process | tRNA processing |
| GO_0006418 | Biological process | tRNA aminoacylation for protein translation |
| GO_0005759 | Cellular component | mitochondrial matrix |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0000049 | Molecular function | tRNA binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0004826 | Molecular function | phenylalanine-tRNA ligase activity |
| GO_0005524 | Molecular function | ATP binding |
| Gene name | FARS2 |
| Protein name | phenylalanine--tRNA ligase (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase) Phenylalanyl-tRNA synthetase 2, mitochondrial phenylalanine--tRNA ligase (EC 6.1.1.20) Phenylalanine--tRNA ligase, mitochondrial (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase) (PheRS) |
| Synonyms | FARS1 HSPC320 |
| Description | FUNCTION: Is responsible for the charging of tRNA(Phe) with phenylalanine in mitochondrial translation. To a lesser extent, also catalyzes direct attachment of m-Tyr (an oxidized version of Phe) to tRNA(Phe), thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins. . |
| Accessions | O95363 ENST00000602691.1 R4GMX6 A0A3B3ITR6 Q5JRF7 ENST00000324331.10 ENST00000274680.9 ENST00000445533.1 ENST00000648580.1 |