Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 100% | 5671.88 | 328 / 328 | 97% | 516.73 | 173 / 178 |
| thymus | 100% | 13014.14 | 652 / 653 | 87% | 598.07 | 527 / 605 |
| lung | 94% | 3520.31 | 546 / 578 | 91% | 518.69 | 1055 / 1155 |
| prostate | 84% | 1862.77 | 207 / 245 | 98% | 423.19 | 490 / 502 |
| stomach | 75% | 3769.14 | 270 / 359 | 98% | 1118.85 | 279 / 286 |
| intestine | 58% | 19852.92 | 561 / 966 | 98% | 1364.86 | 515 / 527 |
| breast | 53% | 1346.05 | 244 / 459 | 96% | 364.52 | 1077 / 1118 |
| kidney | 100% | 8929.85 | 89 / 89 | 37% | 82.41 | 334 / 901 |
| bladder | 33% | 704.90 | 7 / 21 | 78% | 531.84 | 394 / 504 |
| ovary | 2% | 20.51 | 3 / 180 | 99% | 458.91 | 424 / 430 |
| esophagus | 23% | 247.70 | 329 / 1445 | 77% | 490.91 | 141 / 183 |
| uterus | 9% | 202.96 | 15 / 170 | 61% | 288.66 | 278 / 459 |
| adrenal gland | 49% | 448.47 | 126 / 258 | 4% | 8.32 | 10 / 230 |
| tonsil | 0% | 0 | 0 / 0 | 40% | 81.89 | 18 / 45 |
| skin | 35% | 394.16 | 638 / 1809 | 0% | 0.80 | 1 / 472 |
| liver | 3% | 27.53 | 7 / 226 | 22% | 95.04 | 90 / 406 |
| brain | 21% | 218.41 | 555 / 2642 | 0% | 0 | 0 / 705 |
| adipose | 1% | 13.36 | 14 / 1204 | 0% | 0 | 0 / 0 |
| peripheral blood | 1% | 8.04 | 7 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 2.94 | 5 / 1335 | 0% | 0 | 0 / 0 |
| heart | 0% | 1.56 | 2 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0023019 | Biological process | signal transduction involved in regulation of gene expression |
| GO_0008284 | Biological process | positive regulation of cell population proliferation |
| GO_0001657 | Biological process | ureteric bud development |
| GO_0048863 | Biological process | stem cell differentiation |
| GO_2000648 | Biological process | positive regulation of stem cell proliferation |
| GO_0098609 | Biological process | cell-cell adhesion |
| GO_2000048 | Biological process | negative regulation of cell-cell adhesion mediated by cadherin |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0016323 | Cellular component | basolateral plasma membrane |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0009986 | Cellular component | cell surface |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016328 | Cellular component | lateral plasma membrane |
| GO_0005923 | Cellular component | bicellular tight junction |
| GO_0044877 | Molecular function | protein-containing complex binding |
| GO_0098641 | Molecular function | cadherin binding involved in cell-cell adhesion |
| GO_0005515 | Molecular function | protein binding |
| Gene name | EPCAM |
| Protein name | Epithelial cell adhesion molecule (Tumor-associated calcium signal transducer 1) Epithelial cell adhesion molecule (Ep-CAM) (Adenocarcinoma-associated antigen) (Cell surface glycoprotein Trop-1) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Epithelial glycoprotein 314) (EGP314) (hEGP314) (KS 1/4 antigen) (KSA) (Major gastrointestinal tumor-associated protein GA733-2) (Tumor-associated calcium signal transducer 1) (CD antigen CD326) |
| Synonyms | M4S1 TROP1 MIC18 GA733-2 M1S2 TACSTD1 |
| Description | FUNCTION: May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E. . FUNCTION: May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E. . FUNCTION: May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E. . |
| Accessions | ENST00000263735.9 ENST00000456133.5 B5MCA4 P16422 ENST00000419334.1 C9JKY3 ENST00000405271.5 |