DYNLT3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0045931Biological processpositive regulation of mitotic cell cycle
GO_0051301Biological processcell division
GO_0007018Biological processmicrotubule-based movement
GO_0007346Biological processregulation of mitotic cell cycle
GO_0061673Cellular componentmitotic spindle astral microtubule
GO_0000776Cellular componentkinetochore
GO_0005868Cellular componentcytoplasmic dynein complex
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0045505Molecular functiondynein intermediate chain binding
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameDYNLT3
Protein nameDynein light chain Tctex-type 3 (Protein 91/23) (T-complex-associated testis-expressed 1-like)
Dynein light chain Tctex-type 3
SynonymsTCTE1XL
TCTE1L
DescriptionFUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis (By similarity). .

FUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis. .

FUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis. .

AccessionsP51808
F2Z328
A6NGJ0
ENST00000432389.2
ENST00000378578.9
ENST00000378581.7