Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 24 studies | 39% ± 18% | |
macrophage | 16 studies | 36% ± 16% | |
astrocyte | 13 studies | 38% ± 17% | |
microglial cell | 13 studies | 35% ± 13% | |
mast cell | 13 studies | 31% ± 8% | |
fibroblast | 12 studies | 33% ± 14% | |
oligodendrocyte precursor cell | 10 studies | 37% ± 17% | |
glutamatergic neuron | 9 studies | 41% ± 25% | |
myeloid cell | 9 studies | 36% ± 21% | |
epithelial cell | 9 studies | 33% ± 18% | |
adipocyte | 9 studies | 37% ± 9% | |
GABAergic neuron | 8 studies | 45% ± 20% | |
pericyte | 8 studies | 27% ± 11% | |
oligodendrocyte | 8 studies | 30% ± 10% | |
smooth muscle cell | 8 studies | 28% ± 10% | |
natural killer cell | 7 studies | 22% ± 7% | |
interneuron | 6 studies | 45% ± 20% | |
ciliated cell | 6 studies | 23% ± 8% | |
endothelial cell of lymphatic vessel | 6 studies | 37% ± 15% | |
CD16-negative, CD56-bright natural killer cell, human | 5 studies | 21% ± 4% | |
cardiac muscle cell | 5 studies | 26% ± 5% | |
dendritic cell | 5 studies | 26% ± 5% | |
T cell | 5 studies | 26% ± 6% | |
monocyte | 5 studies | 37% ± 17% | |
goblet cell | 5 studies | 34% ± 28% | |
club cell | 5 studies | 28% ± 9% | |
alveolar macrophage | 5 studies | 52% ± 21% | |
type I pneumocyte | 5 studies | 34% ± 8% | |
type II pneumocyte | 5 studies | 29% ± 8% | |
granule cell | 4 studies | 26% ± 6% | |
neuron | 4 studies | 46% ± 16% | |
mucosal invariant T cell | 4 studies | 22% ± 6% | |
Mueller cell | 4 studies | 27% ± 6% | |
amacrine cell | 4 studies | 21% ± 2% | |
retinal cone cell | 4 studies | 34% ± 7% | |
retinal rod cell | 4 studies | 25% ± 8% | |
endothelial cell of vascular tree | 4 studies | 35% ± 19% | |
basal cell | 4 studies | 41% ± 25% | |
gamma-delta T cell | 4 studies | 17% ± 1% | |
endothelial cell of sinusoid | 3 studies | 36% ± 12% | |
GABAergic interneuron | 3 studies | 26% ± 6% | |
CD4-positive, alpha-beta T cell | 3 studies | 19% ± 3% | |
mesothelial cell | 3 studies | 41% ± 13% | |
vein endothelial cell | 3 studies | 42% ± 26% | |
GABAergic amacrine cell | 3 studies | 20% ± 6% | |
glycinergic amacrine cell | 3 studies | 23% ± 4% | |
retina horizontal cell | 3 studies | 21% ± 4% | |
retinal ganglion cell | 3 studies | 24% ± 8% | |
hepatocyte | 3 studies | 42% ± 22% | |
ependymal cell | 3 studies | 33% ± 15% | |
enteroendocrine cell | 3 studies | 23% ± 3% | |
capillary endothelial cell | 3 studies | 32% ± 2% | |
respiratory goblet cell | 3 studies | 33% ± 15% | |
lymphocyte | 3 studies | 32% ± 12% | |
transit amplifying cell | 3 studies | 40% ± 34% | |
CD16-positive, CD56-dim natural killer cell, human | 3 studies | 21% ± 6% | |
CD8-positive, alpha-beta T cell | 3 studies | 20% ± 2% | |
endothelial cell of artery | 3 studies | 21% ± 5% | |
mural cell | 3 studies | 36% ± 9% | |
abnormal cell | 3 studies | 31% ± 18% | |
mucus secreting cell | 3 studies | 29% ± 7% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 3010.21 | 1445 / 1445 | 100% | 25.20 | 183 / 183 |
intestine | 100% | 3352.77 | 966 / 966 | 99% | 21.90 | 520 / 527 |
lung | 100% | 3967.50 | 577 / 578 | 98% | 16.42 | 1133 / 1155 |
stomach | 100% | 2486.53 | 359 / 359 | 98% | 25.03 | 279 / 286 |
breast | 100% | 4190.22 | 459 / 459 | 97% | 25.78 | 1080 / 1118 |
prostate | 100% | 2364.10 | 245 / 245 | 96% | 22.39 | 482 / 502 |
thymus | 100% | 3078.70 | 653 / 653 | 95% | 20.26 | 573 / 605 |
bladder | 100% | 3637.19 | 21 / 21 | 95% | 17.01 | 477 / 504 |
kidney | 100% | 1702.45 | 89 / 89 | 94% | 20.67 | 850 / 901 |
pancreas | 99% | 1554.67 | 324 / 328 | 94% | 16.67 | 167 / 178 |
ovary | 100% | 3691.42 | 180 / 180 | 92% | 10.36 | 396 / 430 |
brain | 91% | 1228.52 | 2405 / 2642 | 98% | 15.67 | 688 / 705 |
uterus | 100% | 3733.39 | 170 / 170 | 86% | 11.49 | 394 / 459 |
skin | 100% | 4170.16 | 1809 / 1809 | 86% | 10.44 | 404 / 472 |
adrenal gland | 100% | 2560.95 | 257 / 258 | 79% | 8.78 | 181 / 230 |
liver | 97% | 1059.23 | 220 / 226 | 61% | 5.75 | 247 / 406 |
blood vessel | 100% | 3321.00 | 1335 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 4520.19 | 1203 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 1721.04 | 240 / 241 | 0% | 0 | 0 / 0 |
muscle | 99% | 1416.57 | 795 / 803 | 0% | 0 | 0 / 0 |
heart | 92% | 1775.11 | 791 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 82% | 12.07 | 37 / 45 |
lymph node | 0% | 0 | 0 / 0 | 62% | 6.54 | 18 / 29 |
eye | 0% | 0 | 0 / 0 | 53% | 4.33 | 42 / 80 |
peripheral blood | 39% | 1467.18 | 358 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0015031 | Biological process | protein transport |
GO_0072659 | Biological process | protein localization to plasma membrane |
GO_0032869 | Biological process | cellular response to insulin stimulus |
GO_0032483 | Biological process | regulation of Rab protein signal transduction |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0030904 | Cellular component | retromer complex |
GO_0005829 | Cellular component | cytosol |
GO_0032593 | Cellular component | insulin-responsive compartment |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0030659 | Cellular component | cytoplasmic vesicle membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0031410 | Cellular component | cytoplasmic vesicle |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
Gene name | DENND4C |
Protein name | DENN domain containing 4C DENN domain-containing protein 4C |
Synonyms | C9orf55B C9orf55 |
Description | FUNCTION: Guanine nucleotide exchange factor (GEF) activating RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound form. Thereby, stimulates SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane in response to insulin. . |
Accessions | ENST00000494124.2 ENST00000361024.6 ENST00000602925.5 [Q5VZ89-1] ENST00000380424.1 R4GMN2 A0A0A0MRX3 Q5VZ89 ENST00000380427.5 X6RAE7 X6R5W5 ENST00000434457.7 [Q5VZ89-7] |