DDX50 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
endothelial cell	10 studies	25% ± 6%	Explore
fibroblast	8 studies	21% ± 5%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	7 studies	16% ± 0%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	7 studies	17% ± 2%	Explore
naive B cell	5 studies	18% ± 3%	Explore
CD4-positive, alpha-beta T cell	5 studies	18% ± 3%	Explore
CD8-positive, alpha-beta T cell	5 studies	17% ± 2%	Explore
B cell	5 studies	18% ± 3%	Explore
epithelial cell	5 studies	30% ± 10%	Explore
astrocyte	5 studies	27% ± 6%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	17% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	16% ± 1%	Explore
neuron	4 studies	26% ± 7%	Explore
regulatory T cell	4 studies	18% ± 3%	Explore
retinal cone cell	4 studies	25% ± 7%	Explore
retinal rod cell	4 studies	21% ± 1%	Explore
GABAergic neuron	4 studies	41% ± 13%	Explore
glutamatergic neuron	4 studies	50% ± 17%	Explore
macrophage	4 studies	19% ± 5%	Explore
gamma-delta T cell	4 studies	23% ± 13%	Explore
T cell	4 studies	17% ± 1%	Explore
oligodendrocyte	4 studies	25% ± 2%	Explore
mature NK T cell	4 studies	16% ± 1%	Explore
hematopoietic precursor cell	3 studies	25% ± 7%	Explore
microglial cell	3 studies	21% ± 3%	Explore
CD16-positive, CD56-dim natural killer cell, human	3 studies	16% ± 1%	Explore
mucosal invariant T cell	3 studies	18% ± 3%	Explore
pericyte	3 studies	19% ± 3%	Explore
smooth muscle cell	3 studies	18% ± 1%	Explore
adipocyte	3 studies	19% ± 3%	Explore
ciliated cell	3 studies	22% ± 5%	Explore
lymphocyte	3 studies	21% ± 1%	Explore
rod bipolar cell	3 studies	21% ± 3%	Explore
oligodendrocyte precursor cell	3 studies	29% ± 6%	Explore
dendritic cell	3 studies	25% ± 5%	Explore
connective tissue cell	3 studies	20% ± 2%	Explore
mast cell	3 studies	23% ± 9%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	34% ± 12%	Explore
basal cell	3 studies	28% ± 7%	Explore
transit amplifying cell	3 studies	30% ± 15%	Explore
interneuron	3 studies	41% ± 19%	Explore
plasmacytoid dendritic cell	3 studies	23% ± 5%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	18% ± 2%	Explore
natural killer cell	3 studies	20% ± 1%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
eye	6 studies	20% ± 4%	Explore
brain	5 studies	39% ± 13%	Explore
peripheral blood	3 studies	18% ± 3%	Explore
liver	3 studies	25% ± 4%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	100%	2718.17	459 / 459	100%	64.06	1118 / 1118
esophagus	100%	2356.24	1445 / 1445	100%	39.48	183 / 183
lung	100%	1939.21	578 / 578	100%	49.25	1155 / 1155
ovary	100%	2979.32	180 / 180	100%	41.94	430 / 430
uterus	100%	3198.68	170 / 170	100%	59.16	459 / 459
thymus	100%	2312.57	653 / 653	100%	64.08	604 / 605
prostate	100%	2330.90	245 / 245	100%	52.23	501 / 502
pancreas	100%	1480.99	327 / 328	100%	48.01	178 / 178
intestine	100%	2586.70	966 / 966	100%	45.81	525 / 527
bladder	100%	3014.62	21 / 21	100%	48.71	502 / 504
stomach	100%	1783.09	359 / 359	99%	39.44	284 / 286
brain	99%	1350.21	2615 / 2642	100%	42.99	705 / 705
kidney	100%	1760.42	89 / 89	98%	42.52	881 / 901
skin	100%	2551.99	1809 / 1809	96%	45.23	454 / 472
adrenal gland	100%	1814.36	258 / 258	96%	48.07	221 / 230
liver	96%	798.30	218 / 226	98%	25.49	397 / 406
adipose	100%	2695.06	1204 / 1204	0%	0	0 / 0
blood vessel	100%	3154.51	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	65.26	29 / 29
spleen	100%	1994.48	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	52.17	45 / 45
ureter	0%	0	0 / 0	100%	19.24	1 / 1
muscle	100%	1516.32	801 / 803	0%	0	0 / 0
heart	96%	1347.31	829 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	95%	34.63	76 / 80
peripheral blood	83%	1493.30	769 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0