DCTPP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0042262Biological processDNA protection
GO_0046076Biological processdTTP catabolic process
GO_0009143Biological processnucleoside triphosphate catabolic process
GO_0006253Biological processdCTP catabolic process
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005739Cellular componentmitochondrion
GO_0005634Cellular componentnucleus
GO_0032556Molecular functionpyrimidine deoxyribonucleotide binding
GO_0047840Molecular functiondCTP diphosphatase activity
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0047429Molecular functionnucleoside triphosphate diphosphatase activity
GO_0000287Molecular functionmagnesium ion binding

IV. Literature review

[source]
Gene nameDCTPP1
Protein namedCTP pyrophosphatase 1
dCTP pyrophosphatase 1 (EC 3.6.1.12) (Deoxycytidine-triphosphatase 1) (dCTPase 1) (RS21C6) (XTP3-transactivated gene A protein)
SynonymsXTP3TPA
CDA03
DescriptionFUNCTION: Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. .

AccessionsENST00000565758.1
H3BPN2
ENST00000568434.1
ENST00000678016.1
ENST00000567983.1
ENST00000319285.5
ENST00000568973.5
Q9H773
H3BSA6