Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte precursor cell | 14 studies | 76% ± 17% | |
glutamatergic neuron | 12 studies | 52% ± 20% | |
GABAergic neuron | 11 studies | 43% ± 20% | |
astrocyte | 9 studies | 35% ± 22% | |
endothelial cell | 5 studies | 50% ± 16% | |
interneuron | 5 studies | 53% ± 21% | |
oligodendrocyte | 5 studies | 36% ± 23% | |
neuron | 4 studies | 45% ± 22% | |
microglial cell | 4 studies | 41% ± 22% | |
plasma cell | 4 studies | 24% ± 6% | |
type II pneumocyte | 4 studies | 19% ± 2% | |
GABAergic interneuron | 3 studies | 37% ± 7% | |
GABAergic amacrine cell | 3 studies | 53% ± 15% | |
amacrine cell | 3 studies | 38% ± 5% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 16 studies | 37% ± 18% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 96% | 679.07 | 2544 / 2642 | 83% | 4.21 | 588 / 705 |
lung | 73% | 162.62 | 424 / 578 | 13% | 0.82 | 155 / 1155 |
adrenal gland | 49% | 105.48 | 127 / 258 | 14% | 0.54 | 32 / 230 |
intestine | 42% | 52.98 | 404 / 966 | 0% | 0.01 | 2 / 527 |
spleen | 34% | 51.49 | 83 / 241 | 0% | 0 | 0 / 0 |
prostate | 26% | 29.84 | 63 / 245 | 0% | 0.01 | 2 / 502 |
kidney | 20% | 23.11 | 18 / 89 | 1% | 0.02 | 11 / 901 |
ovary | 14% | 17.51 | 26 / 180 | 1% | 0.03 | 6 / 430 |
breast | 15% | 18.53 | 71 / 459 | 0% | 0.01 | 4 / 1118 |
stomach | 11% | 8.55 | 39 / 359 | 2% | 0.07 | 6 / 286 |
skin | 4% | 4.48 | 75 / 1809 | 7% | 0.22 | 31 / 472 |
esophagus | 2% | 2.30 | 34 / 1445 | 5% | 0.72 | 10 / 183 |
uterus | 5% | 13.76 | 8 / 170 | 2% | 0.07 | 9 / 459 |
adipose | 5% | 6.20 | 58 / 1204 | 0% | 0 | 0 / 0 |
liver | 0% | 0 | 0 / 226 | 4% | 0.14 | 16 / 406 |
blood vessel | 4% | 6.16 | 47 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.17 | 1 / 29 |
thymus | 2% | 2.30 | 16 / 653 | 0% | 0.01 | 3 / 605 |
pancreas | 1% | 0.95 | 3 / 328 | 1% | 0.06 | 2 / 178 |
peripheral blood | 1% | 1.03 | 9 / 929 | 0% | 0 | 0 / 0 |
bladder | 0% | 0 | 0 / 21 | 1% | 0.03 | 4 / 504 |
muscle | 0% | 0.38 | 2 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0021965 | Biological process | spinal cord ventral commissure morphogenesis |
GO_0001764 | Biological process | neuron migration |
GO_0007409 | Biological process | axonogenesis |
GO_0033564 | Biological process | anterior/posterior axon guidance |
GO_0010977 | Biological process | negative regulation of neuron projection development |
GO_0006915 | Biological process | apoptotic process |
GO_0099170 | Biological process | postsynaptic modulation of chemical synaptic transmission |
GO_0098609 | Biological process | cell-cell adhesion |
GO_0048671 | Biological process | negative regulation of collateral sprouting |
GO_2000171 | Biological process | negative regulation of dendrite development |
GO_0007411 | Biological process | axon guidance |
GO_0033563 | Biological process | dorsal/ventral axon guidance |
GO_0098839 | Cellular component | postsynaptic density membrane |
GO_0098685 | Cellular component | Schaffer collateral - CA1 synapse |
GO_0005886 | Cellular component | plasma membrane |
GO_0009986 | Cellular component | cell surface |
GO_0005829 | Cellular component | cytosol |
GO_0044295 | Cellular component | axonal growth cone |
GO_0004888 | Molecular function | transmembrane signaling receptor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | DCC |
Protein name | DCC protein DCC netrin 1 receptor Netrin receptor DCC (Colorectal cancer suppressor) (Immunoglobulin superfamily DCC subclass member 1) (Tumor suppressor protein DCC) Deleted in colorectal cancer protein DCC |
Synonyms | IGDCC1 |
Description | FUNCTION: Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene. . |
Accessions | ENST00000581559.1 ENST00000304775.12 Q16218 H0Y2Q5 ENST00000578080.1 J3QS93 V9GZY6 ENST00000582875.1 ENST00000581580.5 P43146 ENST00000578949.1 J3QRL3 Q49AK4 J3QLT8 ENST00000442544.7 J3QQJ6 V9H089 J3QRM6 ENST00000579349.1 J3QLB0 ENST00000579941.1 J3QKL2 |