CDC42EP3 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
endothelial cell	25 studies	30% ± 12%	Explore
classical monocyte	22 studies	35% ± 15%	Explore
natural killer cell	21 studies	21% ± 4%	Explore
non-classical monocyte	18 studies	35% ± 14%	Explore
mast cell	16 studies	28% ± 10%	Explore
CD8-positive, alpha-beta T cell	15 studies	20% ± 4%	Explore
vein endothelial cell	12 studies	32% ± 16%	Explore
endothelial cell of vascular tree	12 studies	40% ± 13%	Explore
monocyte	11 studies	26% ± 11%	Explore
mucosal invariant T cell	11 studies	26% ± 7%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	21% ± 3%	Explore
mature NK T cell	10 studies	21% ± 3%	Explore
endothelial cell of artery	10 studies	34% ± 13%	Explore
CD4-positive, alpha-beta T cell	10 studies	19% ± 5%	Explore
gamma-delta T cell	10 studies	23% ± 5%	Explore
B cell	9 studies	18% ± 2%	Explore
smooth muscle cell	9 studies	33% ± 16%	Explore
ciliated cell	9 studies	26% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell	9 studies	19% ± 5%	Explore
T cell	8 studies	23% ± 11%	Explore
CD8-positive, alpha-beta memory T cell	8 studies	21% ± 3%	Explore
regulatory T cell	8 studies	19% ± 4%	Explore
capillary endothelial cell	7 studies	27% ± 18%	Explore
retina horizontal cell	6 studies	33% ± 12%	Explore
macrophage	5 studies	18% ± 4%	Explore
neutrophil	5 studies	30% ± 9%	Explore
cardiac muscle cell	5 studies	26% ± 4%	Explore
leukocyte	4 studies	24% ± 5%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	21% ± 5%	Explore
conventional dendritic cell	4 studies	30% ± 6%	Explore
podocyte	4 studies	37% ± 19%	Explore
innate lymphoid cell	4 studies	21% ± 2%	Explore
myeloid cell	4 studies	28% ± 9%	Explore
basal cell	4 studies	22% ± 4%	Explore
memory B cell	4 studies	19% ± 6%	Explore
glutamatergic neuron	4 studies	23% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	20% ± 4%	Explore
pancreatic A cell	3 studies	46% ± 17%	Explore
type B pancreatic cell	3 studies	46% ± 20%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	24% ± 5%	Explore
intermediate monocyte	3 studies	47% ± 18%	Explore
CD4-positive helper T cell	3 studies	25% ± 6%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	24% ± 3%	Explore
GABAergic neuron	3 studies	36% ± 9%	Explore
dendritic cell	3 studies	33% ± 9%	Explore
goblet cell	3 studies	25% ± 9%	Explore
melanocyte	3 studies	43% ± 30%	Explore
T-helper 17 cell	3 studies	18% ± 1%	Explore
interneuron	3 studies	30% ± 9%	Explore
enteroendocrine cell	3 studies	27% ± 10%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	12 studies	24% ± 6%	Explore
lung	6 studies	22% ± 6%	Explore
pancreas	3 studies	37% ± 13%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	6810.77	244 / 245	100%	28.28	501 / 502
lung	100%	4368.89	576 / 578	96%	22.69	1105 / 1155
thymus	98%	2358.41	638 / 653	97%	20.34	587 / 605
skin	94%	5634.21	1697 / 1809	97%	29.13	458 / 472
ovary	94%	2590.19	169 / 180	94%	11.30	403 / 430
breast	100%	5761.59	459 / 459	88%	12.65	979 / 1118
uterus	99%	9884.15	169 / 170	87%	17.58	399 / 459
bladder	100%	6485.62	21 / 21	86%	13.53	435 / 504
intestine	99%	4999.77	955 / 966	82%	7.96	433 / 527
kidney	100%	3766.39	89 / 89	80%	9.64	724 / 901
stomach	91%	1814.74	325 / 359	79%	9.24	226 / 286
esophagus	77%	4208.94	1107 / 1445	84%	12.51	153 / 183
adrenal gland	47%	691.06	120 / 258	72%	12.13	166 / 230
pancreas	18%	221.74	58 / 328	98%	16.53	175 / 178
spleen	100%	2948.84	241 / 241	0%	0	0 / 0
blood vessel	100%	5307.73	1334 / 1335	0%	0	0 / 0
adipose	100%	6854.42	1203 / 1204	0%	0	0 / 0
peripheral blood	100%	7879.74	925 / 929	0%	0	0 / 0
muscle	100%	5652.79	799 / 803	0%	0	0 / 0
heart	97%	4055.71	835 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	93%	10.04	27 / 29
tonsil	0%	0	0 / 0	87%	10.39	39 / 45
brain	17%	215.62	462 / 2642	41%	3.23	289 / 705
eye	0%	0	0 / 0	36%	2.71	29 / 80
liver	9%	113.00	20 / 226	15%	1.21	62 / 406
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1