CD34 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CD34 at tissue level.

III. Associated gene sets

GO_0048870Biological processcell motility
GO_0071971Biological processextracellular exosome assembly
GO_0030097Biological processhemopoiesis
GO_0032703Biological processnegative regulation of interleukin-2 production
GO_0003094Biological processglomerular filtration
GO_0010629Biological processnegative regulation of gene expression
GO_0042482Biological processpositive regulation of odontogenesis
GO_0045766Biological processpositive regulation of angiogenesis
GO_0007160Biological processcell-matrix adhesion
GO_0007165Biological processsignal transduction
GO_0010628Biological processpositive regulation of gene expression
GO_0038001Biological processparacrine signaling
GO_0072011Biological processglomerular endothelium development
GO_0071425Biological processhematopoietic stem cell proliferation
GO_0035759Biological processmesangial cell-matrix adhesion
GO_0050900Biological processleukocyte migration
GO_0001935Biological processendothelial cell proliferation
GO_0072254Biological processmetanephric glomerular mesangial cell differentiation
GO_0003158Biological processendothelium development
GO_2001214Biological processpositive regulation of vasculogenesis
GO_0071657Biological processpositive regulation of granulocyte colony-stimulating factor production
GO_0061042Biological processvascular wound healing
GO_0001894Biological processtissue homeostasis
GO_0060290Biological processtransdifferentiation
GO_0098609Biological processcell-cell adhesion
GO_0072089Biological processstem cell proliferation
GO_0016324Cellular componentapical plasma membrane
GO_0009897Cellular componentexternal side of plasma membrane
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0005764Cellular componentlysosome
GO_0009925Cellular componentbasal plasma membrane
GO_0045171Cellular componentintercellular bridge
GO_0005737Cellular componentcytoplasm
GO_0036053Cellular componentglomerular endothelium fenestra
GO_0030246Molecular functioncarbohydrate binding
GO_0061629Molecular functionRNA polymerase II-specific DNA-binding transcription factor binding
GO_0005515Molecular functionprotein binding
GO_0043199Molecular functionsulfate binding

IV. Literature review

[source]
Gene nameCD34
Protein nameCD34 antigen
Hematopoietic progenital cell antigen CD34
CD34 molecule
Hematopoietic progenitor cell antigen CD34
Hematopoietic progenitor cell antigen CD34 (CD antigen CD34)
Synonyms
DescriptionFUNCTION: Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.

AccessionsENST00000367036.7
Q8IUM0
ENST00000356522.4 [P28906-2]
Q3C1E7
ENST00000310833.12 [P28906-1]
Q5JTA5
P28906
Q9UH97