CCDC69 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
natural killer cell	29 studies	25% ± 6%	Explore
classical monocyte	20 studies	30% ± 13%	Explore
plasmacytoid dendritic cell	16 studies	38% ± 13%	Explore
B cell	14 studies	27% ± 8%	Explore
non-classical monocyte	14 studies	26% ± 12%	Explore
naive B cell	14 studies	22% ± 4%	Explore
endothelial cell	12 studies	21% ± 7%	Explore
ciliated cell	12 studies	26% ± 7%	Explore
CD8-positive, alpha-beta T cell	12 studies	20% ± 4%	Explore
plasma cell	11 studies	27% ± 10%	Explore
CD16-positive, CD56-dim natural killer cell, human	11 studies	34% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	28% ± 8%	Explore
gamma-delta T cell	11 studies	30% ± 10%	Explore
regulatory T cell	10 studies	20% ± 3%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	24% ± 5%	Explore
monocyte	8 studies	22% ± 4%	Explore
memory B cell	8 studies	18% ± 3%	Explore
mature NK T cell	8 studies	26% ± 7%	Explore
adipocyte	8 studies	24% ± 8%	Explore
CD4-positive, alpha-beta memory T cell	7 studies	19% ± 3%	Explore
CD8-positive, alpha-beta memory T cell	7 studies	26% ± 6%	Explore
mucosal invariant T cell	7 studies	21% ± 4%	Explore
precursor B cell	6 studies	39% ± 12%	Explore
T cell	6 studies	20% ± 5%	Explore
vein endothelial cell	6 studies	24% ± 7%	Explore
plasmablast	5 studies	49% ± 16%	Explore
CD4-positive, alpha-beta T cell	5 studies	21% ± 5%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	5 studies	20% ± 2%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	25% ± 5%	Explore
lymphocyte	4 studies	19% ± 2%	Explore
immature B cell	4 studies	35% ± 13%	Explore
endothelial cell of vascular tree	4 studies	18% ± 3%	Explore
innate lymphoid cell	4 studies	26% ± 5%	Explore
exhausted T cell	3 studies	23% ± 5%	Explore
IgG plasma cell	3 studies	17% ± 1%	Explore
pro-B cell	3 studies	24% ± 4%	Explore
germinal center B cell	3 studies	39% ± 3%	Explore
intermediate monocyte	3 studies	45% ± 22%	Explore
dendritic cell	3 studies	37% ± 19%	Explore
group 3 innate lymphoid cell	3 studies	28% ± 7%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
peripheral blood	13 studies	26% ± 9%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	99%	7898.89	572 / 578	96%	25.86	1111 / 1155
bladder	100%	16677.14	21 / 21	95%	20.14	479 / 504
adrenal gland	100%	17966.36	258 / 258	87%	69.80	201 / 230
pancreas	93%	3773.36	305 / 328	94%	22.36	168 / 178
breast	95%	11425.49	434 / 459	90%	16.26	1010 / 1118
esophagus	96%	16965.19	1384 / 1445	89%	16.58	162 / 183
intestine	96%	18377.08	930 / 966	88%	14.52	463 / 527
prostate	86%	5159.95	210 / 245	97%	20.75	486 / 502
uterus	93%	5613.38	158 / 170	90%	16.09	411 / 459
liver	65%	2691.46	147 / 226	91%	16.62	371 / 406
ovary	91%	4315.24	163 / 180	65%	6.21	281 / 430
stomach	59%	5909.94	212 / 359	90%	19.08	256 / 286
thymus	49%	1673.31	322 / 653	97%	22.18	585 / 605
skin	44%	1651.16	787 / 1809	69%	12.44	327 / 472
kidney	17%	569.89	15 / 89	91%	15.24	818 / 901
lymph node	0%	0	0 / 0	100%	159.05	29 / 29
muscle	100%	13426.19	803 / 803	0%	0	0 / 0
spleen	100%	9565.76	241 / 241	0%	0	0 / 0
adipose	100%	14608.71	1203 / 1204	0%	0	0 / 0
peripheral blood	98%	11360.48	907 / 929	0%	0	0 / 0
heart	97%	11202.97	837 / 861	0%	0	0 / 0
blood vessel	95%	6317.13	1265 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	93%	20.54	42 / 45
brain	4%	109.36	99 / 2642	76%	7.03	536 / 705
eye	0%	0	0 / 0	33%	2.83	26 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1