CCDC25 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
endothelial cell	11 studies	23% ± 10%	Explore
endothelial cell of lymphatic vessel	8 studies	22% ± 6%	Explore
natural killer cell	6 studies	19% ± 3%	Explore
epithelial cell	6 studies	37% ± 17%	Explore
enterocyte	5 studies	23% ± 5%	Explore
CD8-positive, alpha-beta T cell	5 studies	18% ± 2%	Explore
effector CD8-positive, alpha-beta T cell	4 studies	18% ± 3%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	4 studies	17% ± 0%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	4 studies	18% ± 3%	Explore
B cell	4 studies	18% ± 3%	Explore
CD4-positive, alpha-beta T cell	4 studies	19% ± 3%	Explore
fibroblast	4 studies	29% ± 10%	Explore
ciliated cell	4 studies	35% ± 11%	Explore
plasmacytoid dendritic cell	4 studies	20% ± 4%	Explore
regulatory T cell	4 studies	17% ± 1%	Explore
pancreatic A cell	3 studies	28% ± 3%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	18% ± 1%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	18% ± 1%	Explore
non-classical monocyte	3 studies	18% ± 4%	Explore
abnormal cell	3 studies	19% ± 4%	Explore
neuron	3 studies	22% ± 6%	Explore
GABAergic neuron	3 studies	33% ± 5%	Explore
astrocyte	3 studies	22% ± 5%	Explore
glutamatergic neuron	3 studies	48% ± 7%	Explore
dendritic cell	3 studies	26% ± 5%	Explore
pancreatic ductal cell	3 studies	31% ± 10%	Explore
basal cell	3 studies	34% ± 13%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	16% ± 0%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	4 studies	31% ± 9%	Explore
pancreas	3 studies	28% ± 4%	Explore
peripheral blood	3 studies	19% ± 2%	Explore
lung	3 studies	29% ± 14%	Explore
liver	3 studies	25% ± 12%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	2765.78	2642 / 2642	100%	40.90	705 / 705
breast	100%	2272.04	459 / 459	100%	31.95	1118 / 1118
esophagus	100%	2028.05	1445 / 1445	100%	24.98	183 / 183
ovary	100%	1644.05	180 / 180	100%	19.45	430 / 430
prostate	100%	1966.00	245 / 245	100%	29.23	502 / 502
thymus	100%	2380.90	653 / 653	100%	36.25	604 / 605
pancreas	99%	1389.55	326 / 328	100%	22.77	178 / 178
uterus	100%	2358.54	170 / 170	99%	27.36	456 / 459
stomach	100%	2003.65	359 / 359	99%	24.59	284 / 286
lung	99%	1503.57	573 / 578	100%	22.56	1155 / 1155
adrenal gland	100%	3492.28	258 / 258	99%	29.94	228 / 230
bladder	100%	2127.76	21 / 21	99%	21.97	499 / 504
kidney	100%	2075.85	89 / 89	99%	26.57	891 / 901
intestine	100%	2240.59	966 / 966	99%	23.73	521 / 527
skin	100%	2291.75	1809 / 1809	98%	30.82	462 / 472
liver	100%	1650.23	226 / 226	97%	17.57	395 / 406
adipose	100%	2206.80	1204 / 1204	0%	0	0 / 0
blood vessel	100%	2371.87	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	24.68	29 / 29
muscle	100%	2542.80	803 / 803	0%	0	0 / 0
spleen	100%	1497.55	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	31.29	45 / 45
ureter	0%	0	0 / 0	100%	6.08	1 / 1
heart	95%	1334.46	819 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	95%	19.02	76 / 80
peripheral blood	43%	962.51	404 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0