Name | Number of supported studies | Average coverage | |
---|---|---|---|
basal cell | 15 studies | 36% ± 18% | |
epithelial cell | 13 studies | 36% ± 18% | |
natural killer cell | 13 studies | 20% ± 4% | |
ciliated cell | 11 studies | 29% ± 8% | |
B cell | 8 studies | 22% ± 7% | |
classical monocyte | 8 studies | 26% ± 14% | |
endothelial cell | 8 studies | 21% ± 7% | |
type I pneumocyte | 7 studies | 24% ± 7% | |
CD16-positive, CD56-dim natural killer cell, human | 7 studies | 21% ± 3% | |
platelet | 7 studies | 36% ± 12% | |
plasmacytoid dendritic cell | 7 studies | 23% ± 5% | |
club cell | 6 studies | 25% ± 5% | |
respiratory goblet cell | 6 studies | 30% ± 14% | |
fibroblast | 6 studies | 25% ± 9% | |
secretory cell | 5 studies | 32% ± 9% | |
CD16-negative, CD56-bright natural killer cell, human | 5 studies | 21% ± 4% | |
CD8-positive, alpha-beta T cell | 5 studies | 20% ± 6% | |
regulatory T cell | 5 studies | 17% ± 2% | |
goblet cell | 5 studies | 26% ± 7% | |
squamous epithelial cell | 4 studies | 53% ± 19% | |
effector memory CD8-positive, alpha-beta T cell | 4 studies | 19% ± 3% | |
megakaryocyte | 4 studies | 40% ± 21% | |
pericyte | 4 studies | 20% ± 5% | |
abnormal cell | 4 studies | 21% ± 3% | |
macrophage | 4 studies | 20% ± 4% | |
glutamatergic neuron | 4 studies | 28% ± 10% | |
hematopoietic stem cell | 4 studies | 27% ± 16% | |
hematopoietic precursor cell | 3 studies | 27% ± 11% | |
hillock cell | 3 studies | 33% ± 12% | |
pancreatic A cell | 3 studies | 20% ± 2% | |
CD4-positive, alpha-beta T cell | 3 studies | 21% ± 3% | |
conventional dendritic cell | 3 studies | 40% ± 16% | |
non-classical monocyte | 3 studies | 32% ± 8% | |
pro-B cell | 3 studies | 23% ± 4% | |
monocyte | 3 studies | 21% ± 3% | |
germinal center B cell | 3 studies | 18% ± 3% | |
GABAergic neuron | 3 studies | 24% ± 6% | |
pancreatic ductal cell | 3 studies | 44% ± 20% | |
enterocyte | 3 studies | 20% ± 3% | |
keratinocyte | 3 studies | 19% ± 3% | |
gamma-delta T cell | 3 studies | 24% ± 9% | |
astrocyte | 3 studies | 18% ± 2% | |
neuron | 3 studies | 27% ± 14% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 20104.90 | 1445 / 1445 | 100% | 169.93 | 183 / 183 |
ovary | 100% | 6882.03 | 180 / 180 | 100% | 151.65 | 430 / 430 |
pancreas | 100% | 7186.36 | 328 / 328 | 100% | 134.96 | 178 / 178 |
thymus | 100% | 13042.55 | 653 / 653 | 100% | 129.02 | 603 / 605 |
intestine | 100% | 10882.54 | 966 / 966 | 100% | 153.15 | 525 / 527 |
uterus | 100% | 8689.92 | 170 / 170 | 100% | 168.99 | 457 / 459 |
lung | 100% | 9880.60 | 577 / 578 | 99% | 149.23 | 1147 / 1155 |
stomach | 100% | 8518.28 | 359 / 359 | 99% | 136.10 | 283 / 286 |
bladder | 100% | 12139.19 | 21 / 21 | 99% | 194.13 | 498 / 504 |
prostate | 100% | 11818.15 | 245 / 245 | 99% | 90.86 | 495 / 502 |
breast | 100% | 8423.56 | 459 / 459 | 98% | 110.14 | 1100 / 1118 |
kidney | 100% | 8935.31 | 89 / 89 | 98% | 95.11 | 884 / 901 |
skin | 100% | 14927.88 | 1809 / 1809 | 98% | 83.54 | 461 / 472 |
brain | 94% | 4732.28 | 2482 / 2642 | 99% | 53.74 | 695 / 705 |
liver | 100% | 4847.51 | 225 / 226 | 92% | 58.47 | 372 / 406 |
adrenal gland | 100% | 7074.80 | 258 / 258 | 79% | 40.98 | 182 / 230 |
eye | 0% | 0 | 0 / 0 | 100% | 87.63 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 104.50 | 29 / 29 |
spleen | 100% | 8790.88 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 215.55 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 226.83 | 1 / 1 |
adipose | 100% | 6899.86 | 1203 / 1204 | 0% | 0 | 0 / 0 |
muscle | 100% | 6409.82 | 802 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 7517.34 | 1333 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 9820.35 | 918 / 929 | 0% | 0 | 0 / 0 |
heart | 97% | 5472.48 | 833 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_2000310 | Biological process | regulation of NMDA receptor activity |
GO_0060056 | Biological process | mammary gland involution |
GO_0097264 | Biological process | self proteolysis |
GO_0006508 | Biological process | proteolysis |
GO_0050790 | Biological process | regulation of catalytic activity |
GO_0008284 | Biological process | positive regulation of cell population proliferation |
GO_0016241 | Biological process | regulation of macroautophagy |
GO_0032801 | Biological process | receptor catabolic process |
GO_0005576 | Cellular component | extracellular region |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0005739 | Cellular component | mitochondrion |
GO_0005764 | Cellular component | lysosome |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005925 | Cellular component | focal adhesion |
GO_0001533 | Cellular component | cornified envelope |
GO_1904813 | Cellular component | ficolin-1-rich granule lumen |
GO_0005829 | Cellular component | cytosol |
GO_0110158 | Cellular component | calpain complex |
GO_0005737 | Cellular component | cytoplasm |
GO_0008233 | Molecular function | peptidase activity |
GO_0004198 | Molecular function | calcium-dependent cysteine-type endopeptidase activity |
GO_0005509 | Molecular function | calcium ion binding |
GO_0005515 | Molecular function | protein binding |
Gene name | CAPN1 |
Protein name | Calpain 1 Calpain-1 catalytic subunit (EC 3.4.22.52) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (Calpain-1 large subunit) (Cell proliferation-inducing gene 30 protein) (Micromolar-calpain) (muCANP) |
Synonyms | CANPL1 PIG30 |
Description | FUNCTION: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction . Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-387' and 'His-409' . Cleaves and activates caspase-7 (CASP7) . . |
Accessions | ENST00000526966.5 ENST00000533909.5 ENST00000526954.5 E9PLC9 ENST00000524773.5 ENST00000533129.5 E9PJA6 ENST00000533820.5 ENST00000534373.5 E9PSA6 ENST00000527739.5 E9PMC6 ENST00000532285.1 E9PQB3 ENST00000527323.5 ENST00000526468.1 E9PRM1 E9PIA9 ENST00000279247.11 ENST00000529133.5 P07384 E9PLX0 ENST00000527699.5 ENST00000531068.5 E9PJJ3 ENST00000528396.5 E9PL37 |