BLOC1S4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0008089Biological processanterograde axonal transport
GO_0048490Biological processanterograde synaptic vesicle transport
GO_0050885Biological processneuromuscular process controlling balance
GO_0032438Biological processmelanosome organization
GO_0070527Biological processplatelet aggregation
GO_0031175Biological processneuron projection development
GO_0031083Cellular componentBLOC-1 complex
GO_0005829Cellular componentcytosol
GO_1904115Cellular componentaxon cytoplasm
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameBLOC1S4
Protein nameBiogenesis of lysosome-related organelles complex 1 subunit 4 (BLOC-1 subunit 4) (Protein cappuccino homolog)
SynonymsCNO
DescriptionFUNCTION: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. .

AccessionsENST00000320776.5
Q9NUP1