ATXN2L report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
CD8-positive, alpha-beta T cell	8 studies	19% ± 4%	Explore
endothelial cell	8 studies	24% ± 12%	Explore
natural killer cell	7 studies	21% ± 5%	Explore
plasmacytoid dendritic cell	7 studies	22% ± 6%	Explore
B cell	6 studies	21% ± 5%	Explore
CD16-positive, CD56-dim natural killer cell, human	6 studies	24% ± 6%	Explore
CD4-positive, alpha-beta T cell	6 studies	20% ± 5%	Explore
classical monocyte	6 studies	25% ± 10%	Explore
T cell	5 studies	17% ± 1%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	23% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	22% ± 4%	Explore
naive B cell	5 studies	22% ± 6%	Explore
hematopoietic precursor cell	4 studies	30% ± 12%	Explore
microglial cell	4 studies	21% ± 5%	Explore
macrophage	4 studies	21% ± 3%	Explore
ciliated cell	4 studies	27% ± 6%	Explore
glutamatergic neuron	4 studies	38% ± 21%	Explore
gamma-delta T cell	4 studies	25% ± 12%	Explore
CD4-positive, alpha-beta memory T cell	3 studies	27% ± 7%	Explore
conventional dendritic cell	3 studies	42% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	23% ± 6%	Explore
non-classical monocyte	3 studies	32% ± 10%	Explore
interneuron	3 studies	29% ± 16%	Explore
epithelial cell	3 studies	42% ± 15%	Explore
precursor B cell	3 studies	31% ± 14%	Explore
pro-B cell	3 studies	32% ± 17%	Explore
myeloid cell	3 studies	30% ± 9%	Explore
T follicular helper cell	3 studies	20% ± 2%	Explore
type I pneumocyte	3 studies	19% ± 2%	Explore
GABAergic neuron	3 studies	36% ± 14%	Explore
astrocyte	3 studies	26% ± 0%	Explore
oligodendrocyte precursor cell	3 studies	22% ± 3%	Explore
dendritic cell	3 studies	39% ± 20%	Explore
abnormal cell	3 studies	25% ± 2%	Explore
memory B cell	3 studies	25% ± 11%	Explore
regulatory T cell	3 studies	19% ± 3%	Explore
neuron	3 studies	26% ± 2%	Explore
oligodendrocyte	3 studies	20% ± 1%	Explore
innate lymphoid cell	3 studies	15% ± 0%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
brain	6 studies	29% ± 13%	Explore
lung	4 studies	19% ± 4%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	9309.75	1445 / 1445	100%	129.20	183 / 183
ovary	100%	10536.86	180 / 180	100%	111.27	430 / 430
intestine	100%	10933.62	966 / 966	100%	72.44	526 / 527
stomach	100%	8217.30	359 / 359	100%	79.39	285 / 286
skin	100%	9554.30	1808 / 1809	100%	83.45	470 / 472
lung	100%	12365.87	578 / 578	99%	76.81	1147 / 1155
breast	100%	9557.47	459 / 459	99%	69.54	1108 / 1118
thymus	100%	13040.82	653 / 653	99%	54.15	596 / 605
bladder	100%	10315.76	21 / 21	98%	66.19	496 / 504
pancreas	100%	6434.07	328 / 328	98%	55.79	175 / 178
uterus	100%	12638.41	170 / 170	98%	67.56	450 / 459
kidney	100%	9143.82	89 / 89	98%	49.38	882 / 901
prostate	100%	12030.56	245 / 245	98%	50.25	491 / 502
brain	96%	7581.52	2543 / 2642	100%	65.20	703 / 705
adrenal gland	100%	9040.64	258 / 258	96%	48.42	220 / 230
liver	100%	5595.46	226 / 226	88%	32.27	359 / 406
adipose	100%	9014.68	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	71.06	80 / 80
lymph node	0%	0	0 / 0	100%	70.99	29 / 29
spleen	100%	14743.21	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	70.05	45 / 45
ureter	0%	0	0 / 0	100%	32.90	1 / 1
blood vessel	100%	8464.19	1334 / 1335	0%	0	0 / 0
muscle	99%	5034.74	797 / 803	0%	0	0 / 0
heart	99%	5122.24	849 / 861	0%	0	0 / 0
peripheral blood	95%	7684.88	882 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0