Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 100% | 1169.41 | 578 / 578 | 87% | 14.96 | 1005 / 1155 |
| intestine | 89% | 480.56 | 857 / 966 | 88% | 19.83 | 463 / 527 |
| stomach | 84% | 198.57 | 301 / 359 | 88% | 21.22 | 251 / 286 |
| brain | 71% | 208.64 | 1873 / 2642 | 95% | 13.16 | 668 / 705 |
| breast | 81% | 209.04 | 371 / 459 | 81% | 9.22 | 900 / 1118 |
| prostate | 91% | 291.16 | 223 / 245 | 62% | 4.30 | 311 / 502 |
| kidney | 66% | 204.01 | 59 / 89 | 83% | 15.79 | 748 / 901 |
| thymus | 94% | 263.40 | 614 / 653 | 44% | 4.45 | 265 / 605 |
| liver | 86% | 209.61 | 195 / 226 | 47% | 3.97 | 190 / 406 |
| uterus | 71% | 140.97 | 120 / 170 | 60% | 5.78 | 275 / 459 |
| bladder | 67% | 257.62 | 14 / 21 | 57% | 11.00 | 285 / 504 |
| adrenal gland | 88% | 257.38 | 226 / 258 | 35% | 2.27 | 81 / 230 |
| esophagus | 50% | 100.27 | 727 / 1445 | 57% | 4.95 | 104 / 183 |
| pancreas | 31% | 64.78 | 101 / 328 | 76% | 9.18 | 135 / 178 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 46.62 | 29 / 29 |
| spleen | 100% | 5311.87 | 241 / 241 | 0% | 0 | 0 / 0 |
| ovary | 36% | 66.78 | 64 / 180 | 59% | 5.70 | 255 / 430 |
| adipose | 95% | 416.37 | 1140 / 1204 | 0% | 0 | 0 / 0 |
| skin | 17% | 24.09 | 300 / 1809 | 67% | 10.94 | 318 / 472 |
| peripheral blood | 84% | 6679.51 | 776 / 929 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 76% | 10.77 | 34 / 45 |
| blood vessel | 69% | 235.87 | 918 / 1335 | 0% | 0 | 0 / 0 |
| heart | 39% | 70.58 | 340 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 30% | 2.24 | 24 / 80 |
| muscle | 2% | 3.22 | 17 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0050728 | Biological process | negative regulation of inflammatory response |
| GO_0006631 | Biological process | fatty acid metabolic process |
| GO_0009104 | Biological process | lipopolysaccharide catabolic process |
| GO_0005576 | Cellular component | extracellular region |
| GO_0031410 | Cellular component | cytoplasmic vesicle |
| GO_0050528 | Molecular function | acyloxyacyl hydrolase activity |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | AOAH |
| Protein name | Alternative protein AOAH Acyloxyacyl hydrolase Acyloxyacyl hydrolase (EC 3.1.1.77) [Cleaved into: Acyloxyacyl hydrolase small subunit; Acyloxyacyl hydrolase large subunit] |
| Synonyms | |
| Description | FUNCTION: Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides . By breaking down LPS, terminates the host response to bacterial infection and prevents prolonged and damaging inflammatory responses (By similarity). In peritoneal macrophages, seems to be important for recovery from a state of immune tolerance following infection by Gram-negative bacteria (By similarity). . |
| Accessions | A0A087WVT3 P28039 C9JJA7 F8WCP9 ENST00000617267.4 ENST00000612871.4 [P28039-2] ENST00000435386.1 ENST00000617537.5 [P28039-1] ENST00000414637.1 L8E8U0 |