AOAH report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0050728Biological processnegative regulation of inflammatory response
GO_0006631Biological processfatty acid metabolic process
GO_0009104Biological processlipopolysaccharide catabolic process
GO_0005576Cellular componentextracellular region
GO_0031410Cellular componentcytoplasmic vesicle
GO_0050528Molecular functionacyloxyacyl hydrolase activity
GO_0005509Molecular functioncalcium ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameAOAH
Protein nameAlternative protein AOAH
Acyloxyacyl hydrolase
Acyloxyacyl hydrolase (EC 3.1.1.77) [Cleaved into: Acyloxyacyl hydrolase small subunit; Acyloxyacyl hydrolase large subunit]
Synonyms
DescriptionFUNCTION: Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides . By breaking down LPS, terminates the host response to bacterial infection and prevents prolonged and damaging inflammatory responses (By similarity). In peritoneal macrophages, seems to be important for recovery from a state of immune tolerance following infection by Gram-negative bacteria (By similarity). .

AccessionsA0A087WVT3
P28039
C9JJA7
F8WCP9
ENST00000617267.4
ENST00000612871.4 [P28039-2]
ENST00000435386.1
ENST00000617537.5 [P28039-1]
ENST00000414637.1
L8E8U0