AGFG1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006406Biological processmRNA export from nucleus
GO_0045109Biological processintermediate filament organization
GO_0001675Biological processacrosome assembly
GO_0007289Biological processspermatid nucleus differentiation
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0005829Cellular componentcytosol
GO_0005643Cellular componentnuclear pore
GO_0031410Cellular componentcytoplasmic vesicle
GO_0005737Cellular componentcytoplasm
GO_0003677Molecular functionDNA binding
GO_0005096Molecular functionGTPase activator activity
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameAGFG1
Protein nameArf-GAP domain and FG repeat-containing protein 1 (HIV-1 Rev-binding protein) (Nucleoporin-like protein RIP) (Rev-interacting protein) (Rev/Rex activation domain-binding protein)
ArfGAP with FG repeats 1 isoform 4
ArfGAP with FG repeats 1
ArfGAP with FG repeats 1 isoform 3
ArfGAP with FG repeats 1 isoform 2
ArfGAP with FG repeats 1 isoform 1
SynonymsRAB
RIP
HRB
DescriptionFUNCTION: Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication. .

AccessionsENST00000310078.13 [P52594-1]
C9J2I0
A0A0S2Z3Z1
ENST00000456594.1
ENST00000458212.1
P52594
ENST00000373671.7 [P52594-2]
H7C0S7
A0A0S2Z444
ENST00000409315.5
ENST00000409979.6 [P52594-4]
ENST00000409171.5 [P52594-3]
B8ZZY2
A0A0S2Z462
A0A0S2Z3Y3