Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 17 studies | 41% ± 12% | |
astrocyte | 16 studies | 34% ± 16% | |
oligodendrocyte precursor cell | 16 studies | 59% ± 22% | |
endothelial cell | 14 studies | 29% ± 11% | |
macrophage | 14 studies | 23% ± 7% | |
smooth muscle cell | 12 studies | 20% ± 5% | |
type I pneumocyte | 11 studies | 37% ± 12% | |
natural killer cell | 10 studies | 19% ± 3% | |
epithelial cell | 10 studies | 32% ± 12% | |
GABAergic neuron | 10 studies | 43% ± 22% | |
glutamatergic neuron | 10 studies | 42% ± 21% | |
type II pneumocyte | 8 studies | 31% ± 8% | |
classical monocyte | 8 studies | 22% ± 8% | |
endothelial cell of lymphatic vessel | 7 studies | 25% ± 13% | |
club cell | 7 studies | 29% ± 9% | |
respiratory goblet cell | 7 studies | 31% ± 11% | |
CD16-negative, CD56-bright natural killer cell, human | 7 studies | 21% ± 4% | |
neuron | 7 studies | 31% ± 18% | |
pericyte | 7 studies | 22% ± 8% | |
basal cell | 7 studies | 24% ± 4% | |
monocyte | 7 studies | 25% ± 5% | |
mast cell | 7 studies | 25% ± 10% | |
oligodendrocyte | 7 studies | 25% ± 10% | |
goblet cell | 6 studies | 31% ± 23% | |
interneuron | 6 studies | 45% ± 28% | |
microglial cell | 6 studies | 23% ± 7% | |
fibroblast | 6 studies | 21% ± 4% | |
secretory cell | 5 studies | 28% ± 5% | |
hepatocyte | 5 studies | 62% ± 28% | |
brush cell | 5 studies | 52% ± 17% | |
cardiac muscle cell | 5 studies | 43% ± 12% | |
dendritic cell | 5 studies | 25% ± 9% | |
ionocyte | 4 studies | 31% ± 9% | |
non-classical monocyte | 4 studies | 22% ± 10% | |
granule cell | 4 studies | 32% ± 10% | |
retinal ganglion cell | 4 studies | 39% ± 12% | |
CD16-positive, CD56-dim natural killer cell, human | 4 studies | 20% ± 3% | |
myeloid cell | 4 studies | 31% ± 8% | |
retinal pigment epithelial cell | 4 studies | 36% ± 12% | |
lymphocyte | 4 studies | 23% ± 5% | |
Mueller cell | 4 studies | 18% ± 2% | |
luminal cell of prostate epithelium | 4 studies | 42% ± 4% | |
alveolar macrophage | 4 studies | 29% ± 8% | |
hematopoietic precursor cell | 3 studies | 32% ± 20% | |
GABAergic interneuron | 3 studies | 33% ± 7% | |
renal alpha-intercalated cell | 3 studies | 28% ± 5% | |
cholangiocyte | 3 studies | 53% ± 15% | |
muscle cell | 3 studies | 29% ± 13% | |
abnormal cell | 3 studies | 26% ± 5% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 31% ± 6% | |
enteroendocrine cell | 3 studies | 27% ± 5% | |
erythroblast | 3 studies | 21% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 7579.53 | 245 / 245 | 99% | 198.94 | 498 / 502 |
esophagus | 100% | 4261.99 | 1445 / 1445 | 98% | 109.05 | 180 / 183 |
intestine | 100% | 4953.60 | 966 / 966 | 98% | 91.52 | 514 / 527 |
stomach | 100% | 8767.75 | 359 / 359 | 97% | 101.82 | 277 / 286 |
pancreas | 100% | 7760.66 | 328 / 328 | 97% | 120.07 | 172 / 178 |
lung | 100% | 8285.64 | 577 / 578 | 96% | 77.25 | 1108 / 1155 |
brain | 99% | 5244.12 | 2604 / 2642 | 96% | 67.00 | 679 / 705 |
breast | 100% | 4614.56 | 459 / 459 | 93% | 92.35 | 1038 / 1118 |
liver | 100% | 13430.49 | 226 / 226 | 90% | 58.55 | 364 / 406 |
skin | 99% | 3878.73 | 1798 / 1809 | 88% | 68.86 | 414 / 472 |
kidney | 99% | 3721.00 | 88 / 89 | 84% | 47.00 | 754 / 901 |
bladder | 100% | 4844.67 | 21 / 21 | 82% | 46.72 | 411 / 504 |
adrenal gland | 100% | 10358.09 | 258 / 258 | 78% | 35.15 | 180 / 230 |
uterus | 100% | 6334.39 | 170 / 170 | 75% | 34.33 | 346 / 459 |
thymus | 100% | 3491.58 | 651 / 653 | 65% | 19.47 | 391 / 605 |
ovary | 100% | 4668.27 | 180 / 180 | 48% | 12.28 | 205 / 430 |
adipose | 100% | 5147.27 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 9108.27 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 4799.28 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 24.98 | 1 / 1 |
peripheral blood | 99% | 7759.83 | 917 / 929 | 0% | 0 | 0 / 0 |
heart | 95% | 7040.93 | 821 / 861 | 0% | 0 | 0 / 0 |
muscle | 91% | 4827.12 | 732 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 84% | 51.12 | 38 / 45 |
lymph node | 0% | 0 | 0 / 0 | 48% | 12.52 | 14 / 29 |
eye | 0% | 0 | 0 / 0 | 16% | 3.31 | 13 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0014909 | Biological process | smooth muscle cell migration |
GO_0014912 | Biological process | negative regulation of smooth muscle cell migration |
GO_0051793 | Biological process | medium-chain fatty acid catabolic process |
GO_0048240 | Biological process | sperm capacitation |
GO_0007340 | Biological process | acrosome reaction |
GO_0051792 | Biological process | medium-chain fatty acid biosynthetic process |
GO_0046464 | Biological process | acylglycerol catabolic process |
GO_0043401 | Biological process | steroid hormone receptor signaling pathway |
GO_0009611 | Biological process | response to wounding |
GO_0032570 | Biological process | response to progesterone |
GO_0097524 | Cellular component | sperm plasma membrane |
GO_0001669 | Cellular component | acrosomal vesicle |
GO_0036126 | Cellular component | sperm flagellum |
GO_0003707 | Molecular function | nuclear steroid receptor activity |
GO_0004806 | Molecular function | triglyceride lipase activity |
GO_0042562 | Molecular function | hormone binding |
GO_0033878 | Molecular function | hormone-sensitive lipase activity |
GO_0008126 | Molecular function | acetylesterase activity |
GO_0047372 | Molecular function | acylglycerol lipase activity |
Gene name | ABHD2 |
Protein name | Monoacylglycerol lipase ABHD2 (EC 3.1.1.23) (2-arachidonoylglycerol hydrolase) (Abhydrolase domain-containing protein 2) (Acetylesterase) (EC 3.1.1.6) (Lung alpha/beta hydrolase 2) (Progesterone-sensitive lipase) (EC 3.1.1.79) (Protein PHPS1-2) Abhydrolase domain containing 2, isoform CRA_a (Testicular tissue protein Li 6) Abhydrolase domain containing 2, acylglycerol lipase |
Synonyms | hCG_28637 LABH2 |
Description | FUNCTION: Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane . Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA) . Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester . Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation . May also play a role in smooth muscle cells migration (By similarity). . |
Accessions | P08910 ENST00000569411.5 ENST00000565973.5 ENST00000565066.5 A0A024RC89 H3BUZ6 H3BN19 H3BMT2 ENST00000569550.5 ENST00000352732.10 |