Name | multi-pass translocon complex |
ID | GO_0160064 |
collection_id | Cellular component |
Exact synonym | MPT complex |
Description | A protein complex that mediates the insertion of multi-pass transmembrane proteins into endoplasmic reticulum (ER) membrane. Substrates enter via the lateral gate of the Sec61 translocon. The complex comprises the GEL subcomplex (composed of RAB5IF/OPTI and TMCO1), the BOS subcomplex (composed of NCLN/Nicalin, NOMO and TMEM147) and the PAT subcomplex (composed of WDR83OS/Asterix and CCDC47). |
Related synonym | TMCO1 translocon |
External URL | |
Genes |