multi-pass translocon complex

I. Literature review

[source]
Namemulti-pass translocon complex
IDGO_0160064
collection_id

Cellular component

Exact synonym

MPT complex

Description

A protein complex that mediates the insertion of multi-pass transmembrane proteins into endoplasmic reticulum (ER) membrane. Substrates enter via the lateral gate of the Sec61 translocon. The complex comprises the GEL subcomplex (composed of RAB5IF/OPTI and TMCO1), the BOS subcomplex (composed of NCLN/Nicalin, NOMO and TMEM147) and the PAT subcomplex (composed of WDR83OS/Asterix and CCDC47).

Related synonym

TMCO1 translocon

External URL
Genes