NOMO3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of NOMO3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of NOMO3 at tissue level.

III. Associated gene sets

GO_0003140Biological processdetermination of left/right asymmetry in lateral mesoderm
GO_1900108Biological processnegative regulation of nodal signaling pathway
GO_0160063Biological processmulti-pass transmembrane protein insertion into ER membrane
GO_0005575Cellular componentcellular_component
GO_0160064Cellular componentmulti-pass translocon complex
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0043022Molecular functionribosome binding
GO_0030246Molecular functioncarbohydrate binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameNOMO3
Protein nameNodal modulator 3
NOMO3 protein
NODAL modulator 3
BOS complex subunit NOMO3 (Nodal modulator 3) (pM5 protein 3)
Synonyms
DescriptionFUNCTION: Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes . The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions . .

AccessionsA0A7I2V4D7
Q1LZN2
A0A7I2V2Z5
ENST00000633153.1
ENST00000677260.1
ENST00000611106.4
ENST00000677163.1
ENST00000678192.1
I3NI42
ENST00000678393.1
ENST00000576589.1
A0A7I2V686
ENST00000570346.1
ENST00000676550.1
ENST00000616708.4
ENST00000633882.1
ENST00000572033.1
I3L2X2
I3L1G6
ENST00000632143.1
I3L0Q6
ENST00000678538.1
ENST00000576460.5
J3KN36
A0A7I2V3P4
P69849
ENST00000676846.1
I3L516
ENST00000263012.10
A0A7I2V2V8
ENST00000619364.2
ENST00000677781.1
A0A7I2V6B0
ENST00000575225.5
ENST00000677777.1
ENST00000634143.1
A0A7I2V4T6
ENST00000399336.9
ENST00000677912.1