| Name | MHC class I peptide loading complex |
| ID | GO_0042824 |
| collection_id | Cellular component |
| Exact synonym | peptide-loading complex |
| Description | A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules. |
| Related synonym | PLC |
| Comment | Note that although this complex is located in the endoplasmic reticulum, there is some evidence that it may also be found in the Golgi. |
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| Genes |