[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity

I. Literature review

[source]
Name[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity
IDGO_0008467
collection_id

Molecular function

Description

Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate. The [heparan sulfate]-glucosamine 3-sulfate has a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*+/-6S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S.

Related synonym

3'-phosphoadenylyl-sulfate:heparin-glucosamine 3-O-sulfotransferase activity, 3-OST-1 activity, glucosaminyl 3-O-sulfotransferase activity, heparan sulfate D-glucosaminyl 3-O-sulfotransferase activity, heparin-glucosamine 3-O-sulfotransferase activity, heparin-glucosamine 3-O-sulphotransferase activity, isoform/isozyme 1 (3-OST-1, HS3ST1)

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Genes