Name | Number of supported studies | Average coverage | |
---|---|---|---|
retinal cone cell | 6 studies | 29% ± 7% | |
retinal rod cell | 4 studies | 21% ± 6% | |
plasmacytoid dendritic cell | 4 studies | 23% ± 4% |
Insufficient scRNA-seq data for expression of HS3ST3B1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 2622.41 | 226 / 226 | 96% | 16.12 | 388 / 406 |
lung | 99% | 508.26 | 575 / 578 | 91% | 4.30 | 1047 / 1155 |
prostate | 99% | 477.45 | 242 / 245 | 83% | 2.53 | 416 / 502 |
esophagus | 93% | 301.88 | 1344 / 1445 | 86% | 4.03 | 157 / 183 |
breast | 86% | 192.18 | 397 / 459 | 88% | 3.62 | 983 / 1118 |
stomach | 94% | 191.55 | 336 / 359 | 77% | 2.58 | 219 / 286 |
uterus | 84% | 245.54 | 143 / 170 | 77% | 4.95 | 354 / 459 |
kidney | 100% | 763.48 | 89 / 89 | 59% | 2.48 | 532 / 901 |
intestine | 81% | 287.86 | 778 / 966 | 76% | 2.35 | 403 / 527 |
pancreas | 60% | 96.27 | 197 / 328 | 92% | 4.25 | 163 / 178 |
thymus | 96% | 248.37 | 625 / 653 | 56% | 2.42 | 337 / 605 |
skin | 99% | 1315.90 | 1792 / 1809 | 52% | 2.45 | 244 / 472 |
ovary | 98% | 872.88 | 177 / 180 | 50% | 1.21 | 213 / 430 |
bladder | 81% | 296.00 | 17 / 21 | 61% | 2.34 | 305 / 504 |
adrenal gland | 95% | 223.66 | 245 / 258 | 30% | 1.08 | 69 / 230 |
spleen | 100% | 1002.86 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 5.02 | 43 / 45 |
lymph node | 0% | 0 | 0 / 0 | 93% | 8.06 | 27 / 29 |
heart | 86% | 185.10 | 740 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 86% | 677.24 | 795 / 929 | 0% | 0 | 0 / 0 |
adipose | 78% | 163.56 | 937 / 1204 | 0% | 0 | 0 / 0 |
brain | 31% | 54.08 | 829 / 2642 | 43% | 4.02 | 305 / 705 |
muscle | 22% | 33.35 | 175 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 18% | 28.26 | 240 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 5% | 0.23 | 4 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0001658 | Biological process | branching involved in ureteric bud morphogenesis |
GO_0015012 | Biological process | heparan sulfate proteoglycan biosynthetic process |
GO_0015015 | Biological process | heparan sulfate proteoglycan biosynthetic process, enzymatic modification |
GO_0006024 | Biological process | glycosaminoglycan biosynthetic process |
GO_0000139 | Cellular component | Golgi membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0008467 | Molecular function | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity |
GO_0033872 | Molecular function | [heparan sulfate]-glucosamine 3-sulfotransferase 3 activity |
Gene name | HS3ST3B1 |
Protein name | Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (3-OST-3B) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B) |
Synonyms | 3OST3B1 HS3ST3B |
Description | FUNCTION: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate . Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2 . The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry . Unlike HS3ST1/3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate . . |
Accessions | ENST00000466596.5 ENST00000360954.3 Q9Y662 |