HS3ST3A1 | OmnibusX

Name	Number of supported studies	Average coverage
retina horizontal cell	4 studies	41% ± 16%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of HS3ST3A1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	100%	656.71	180 / 180	72%	3.96	309 / 430
esophagus	99%	226.06	1431 / 1445	69%	5.32	127 / 183
prostate	99%	300.65	243 / 245	62%	1.51	312 / 502
lung	92%	103.83	534 / 578	63%	2.73	724 / 1155
uterus	85%	108.40	144 / 170	58%	5.19	266 / 459
intestine	85%	88.76	823 / 966	46%	1.44	240 / 527
skin	79%	480.47	1422 / 1809	35%	2.82	167 / 472
breast	54%	32.05	250 / 459	56%	1.42	629 / 1118
stomach	47%	40.38	170 / 359	60%	1.73	173 / 286
kidney	96%	120.21	85 / 89	10%	1.01	94 / 901
adrenal gland	90%	138.51	233 / 258	15%	0.91	34 / 230
spleen	100%	433.94	241 / 241	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	3.75	28 / 29
tonsil	0%	0	0 / 0	87%	6.19	39 / 45
bladder	43%	34.52	9 / 21	39%	1.63	197 / 504
pancreas	2%	0.82	5 / 328	70%	2.80	124 / 178
heart	64%	94.13	552 / 861	0%	0	0 / 0
thymus	46%	23.94	300 / 653	13%	0.54	81 / 605
liver	52%	25.92	117 / 226	6%	0.89	24 / 406
brain	12%	6.12	321 / 2642	30%	1.23	212 / 705
adipose	39%	19.73	470 / 1204	0%	0	0 / 0
blood vessel	12%	5.78	163 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	5%	0.07	4 / 80
peripheral blood	4%	1.63	35 / 929	0%	0	0 / 0
muscle	2%	1.13	19 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0001658	Biological process	branching involved in ureteric bud morphogenesis
GO_0015015	Biological process	heparan sulfate proteoglycan biosynthetic process, enzymatic modification
GO_0006024	Biological process	glycosaminoglycan biosynthetic process
GO_0000139	Cellular component	Golgi membrane
GO_0016020	Cellular component	membrane
GO_0008467	Molecular function	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity
GO_0033872	Molecular function	[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity
GO_0008146	Molecular function	sulfotransferase activity

Gene name	HS3ST3A1
Protein name	Sulfotransferase (EC 2.8.2.-) Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1) (3-OST-3A) (Heparan sulfate 3-O-sulfotransferase 3A1) (h3-OST-3A)
Synonyms	UNQ2551/PRO6180 3OST3A1 HS3ST3A
Description	FUNCTION: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate . Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2 . The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry . Unlike HS3ST1/3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate . .
Accessions	ENST00000578576.1 J3KSX5 ENST00000284110.2 Q9Y663

HS3ST3A1 report