HS3ST2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0015015Biological processheparan sulfate proteoglycan biosynthetic process, enzymatic modification
GO_0006024Biological processglycosaminoglycan biosynthetic process
GO_0000139Cellular componentGolgi membrane
GO_0016020Cellular componentmembrane
GO_0008467Molecular function[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity
GO_0008146Molecular functionsulfotransferase activity
GO_0033871Molecular function[heparan sulfate]-glucosamine 3-sulfotransferase 2 activity

IV. Literature review

[source]
Gene nameHS3ST2
Protein nameSulfotransferase (EC 2.8.2.-)
Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (3-OST-2) (Heparan sulfate 3-O-sulfotransferase 2) (h3-OST-2)
Synonyms3OST2
UNQ2442/PRO5004
DescriptionFUNCTION: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate . Catalyzes the O-sulfation of glucosamine in GlcA2S-GlcNS . Unlike HS3ST1/3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate . .

AccessionsH3BMR2
ENST00000261374.4
ENST00000473392.1
Q9Y278