Name | mitochondrial permeability transition pore complex |
ID | GO_0005757 |
collection_id | Cellular component |
Exact synonym | MPTP complex, mitochondrial PT pore complex |
Description | A protein complex that connects the inner and outer membranes of animal mitochondria and acts as a pore that can open transiently to allow free diffusion of solutes between the mitochondrial matrix and the cytosol. The pore complex is formed of the voltage-dependent anion channel (VDAC), the adenine nucleotide translocase (ANT) and cyclophilin-D (CyP-D). |
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