mitochondrial permeability transition pore complex

I. Literature review

[source]
Namemitochondrial permeability transition pore complex
IDGO_0005757
collection_id

Cellular component

Exact synonym

MPTP complex, mitochondrial PT pore complex

Description

A protein complex that connects the inner and outer membranes of animal mitochondria and acts as a pore that can open transiently to allow free diffusion of solutes between the mitochondrial matrix and the cytosol. The pore complex is formed of the voltage-dependent anion channel (VDAC), the adenine nucleotide translocase (ANT) and cyclophilin-D (CyP-D).

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Genes