Published data collections

A Single-Cell Transcriptome Atlas of the Human Pancreas

https://doi.org/10.1016/j.cels.2016.09.002Deposited data# 2,126 cells

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

https://doi.org/10.1016/j.cell.2022.01.012Deposited data# 836,148 cells

A cell atlas of human thymic development defines T cell repertoire formation

https://doi.org/10.1126/science.aay3224Deposited data# 255,901 cells

A human breast atlas integrating single-cell proteomics and transcriptomics

https://doi.org/10.1016/j.devcel.2022.05.003Deposited data# 52,681 cells

A human fetal lung cell atlas uncovers proximal-distal gradients of differentiation and key regulators of epithelial fates

https://doi.org/10.1016/j.cell.2022.11.005Deposited data# 142,247 cells

A molecular atlas of the human postmenopausal fallopian tube and ovary from single-cell RNA and ATAC sequencing

https://doi.org/10.1016/j.celrep.2022.111838Deposited data# 86,708 cells

A molecular cell atlas of the human lung from single cell RNA sequencing

https://doi.org/10.1038/s41586-020-2922-4Deposited data# 75,071 cells

A molecular single-cell lung atlas of lethal COVID-19

https://doi.org/10.1038/s41586-021-03569-1Deposited data# 116,313 cells

A proximal-to-distal survey of healthy adult human small intestine and colon epithelium by single-cell transcriptomics

https://doi.org/10.1016/j.jcmgh.2022.02.007Deposited data# 12,590 cells

A single-cell and spatially resolved atlas of human breast cancers

https://doi.org/10.1038/s41588-021-00911-1Deposited data# 100,064 cells

A single-cell atlas of CD19 chimeric antigen receptor T cells

https://doi.org/10.1016/j.ccell.2023.08.015Deposited data# 349,340 cells

A single-cell atlas of human and mouse white adipose tissue

https://doi.org/10.1038/s41586-022-04518-2Deposited data# 166,149 cells

A single-cell atlas of the healthy breast tissues reveals clinically relevant clusters of breast epithelial cells

https://doi.org/10.1016/j.xcrm.2021.100219Deposited data# 31,696 cells

A single-cell atlas of the peripheral immune response in patients with severe COVID-19

https://doi.org/10.1038/s41591-020-0944-yDeposited data# 44,721 cells

A single-cell comparison of adult and fetal human epicardium defines the age-associated changes in epicardial activity

https://doi.org/10.1038/s44161-022-00183-wDeposited data# 60,668 cells

A single-cell transcriptome atlas of the adult human retina

https://doi.org/10.15252/embj.2018100811Deposited data# 19,694 cells

A spatially resolved atlas of the human lung characterizes a gland-associated immune niche

https://doi.org/10.1038/s41588-022-01243-4Deposited data# 193,108 cells

A spatially resolved single cell genomic atlas of the adult human breast

https://doi.org/10.1038/s41586-023-06252-9Deposited data# 831,677 cells

A transcriptional cross species map of pancreatic islet cells

https://doi.org/10.1016/j.molmet.2022.101595Deposited data# 26,474 cells

Abdominal White Adipose Tissue

https://cellxgene.cziscience.com/collections/6b701826-37bb-4356-9792-ff41fc4c3161Deposited data# 72,335 cells

Altered human oligodendrocyte heterogeneity in multiple sclerosis

https://doi.org/10.1038/s41586-019-0903-2Deposited data# 17,799 cells

An atlas of healthy and injured cell states and niches in the human kidney

https://doi.org/10.1038/s41586-023-05769-3Deposited data# 304,652 cells

An integrated cell atlas of the lung in health and disease

https://doi.org/10.1038/s41591-023-02327-2Deposited data# 584,944 cells

Blood and immune development in human fetal bone marrow and Down syndrome

https://doi.org/10.1038/s41586-021-03929-xDeposited data# 156,947 cells

Brain matters: Unveiling the Distinct Contributions of Region, Age, and Sex to Glia diversity and CNS Function

https://doi.org/10.1186/s40478-023-01568-zDeposited data# 45,528 cells

Cell Atlas of The Human Fovea and Peripheral Retina

https://doi.org/10.1038/s41598-020-66092-9Deposited data# 84,982 cells

Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution

https://doi.org/10.1016/j.cell.2020.08.013Deposited data# 98,348 cells

Cell atlas of antigen-presenting and stromal cells from the human intestine

https://doi.org/10.1101/2021.03.28.437379Deposited data# 95,728 cells

Cell atlas of the human ocular anterior segment: Tissue-specific and shared cell types

https://doi.org/10.1073/pnas.2200914119Deposited data# 195,248 cells

Cell type-specific effects of age and sex on human cortical neurons

https://doi.org/10.1101/2023.11.11.566717Deposited data# 37,121 cells

Cells of the adult human heart

https://doi.org/10.1038/s41586-020-2797-4Deposited data# 486,134 cells

Cells of the human intestinal tract mapped across space and time

https://doi.org/10.1038/s41586-021-03852-1Deposited data# 428,469 cells

Cellular development and evolution of the mammalian cerebellum

https://doi.org/10.1038/s41586-023-06884-xDeposited data# 180,956 cells

Cellular heterogeneity of human fallopian tubes in normal and hydrosalpinx disease states identified using scRNA-seq

https://doi.org/10.1016/j.devcel.2022.02.017Deposited data# 77,536 cells

Characteristics of anti-CD19 CAR T cell infusion products associated with efficacy and toxicity in patients with large B cell lymphomas

https://doi.org/10.1038/s41591-020-1061-7Deposited data# 133,405 cells

Charting human development using a multi-endodermal organ atlas and organoid models

https://doi.org/10.1016/j.cell.2021.04.028Deposited data# 155,232 cells

Comparative transcriptomics reveals human-specific cortical features

https://doi.org/10.1126/science.ade9516Deposited data# 156,285 cells

Concerted changes in the pediatric single-cell intestinal ecosystem before and after anti-TNF blockade

https://doi.org/10.1101/2021.09.17.21263540Deposited data# 89,849 cells

Conserved transcriptional connectivity of regulatory T cells in the tumor microenvironment informs new combination cancer therapy strategies

https://doi.org/10.1038/s41590-023-01504-2Deposited data# 82,991 cells

Construction of a human cell landscape at single-cell level

https://doi.org/10.1038/s41586-020-2157-4Deposited data# 599,926 cells

Cross-tissue immune cell analysis reveals tissue-specific features in humans

https://doi.org/10.1126/science.abl5197Deposited data# 329,762 cells

Cryptic exon detection and transcriptomic changes revealed in single-nuclei RNA sequencing of C9ORF72 patients spanning the ALS-FTD spectrum

https://doi.org/10.1007/s00401-023-02599-5Deposited data# 461,290 cells

Developmental cell programs are co-opted in inflammatory skin disease

https://doi.org/10.1126/science.aba6500Deposited data# 195,739 cells

Differential cell composition and split epidermal differentiation in human palm, sole, and hip skin

https://doi.org/10.1016/j.celrep.2023.111994Deposited data# 15,243 cells

Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps

https://doi.org/10.1016/j.cell.2021.11.031Deposited data# 133,507 cells

Direct Exposure to SARS-CoV-2 and Cigarette Smoke Increases Infection Severity and Alters the Stem Cell-Derived Airway Repair Response

https://doi.org/10.1016/j.stem.2020.11.010Deposited data# 19,361 cells

Distinct microbial and immune niches of the human colon

https://doi.org/10.1038/s41590-020-0602-zDeposited data# 41,650 cells

Dysregulated lung stroma drives emphysema exacerbation by potentiating resident lymphocytes to suppress an epithelial stem cell reservoir

https://doi.org/10.1016/j.immuni.2023.01.032Deposited data# 57,747 cells

Dysregulation of brain and choroid plexus cell types in severe COVID-19

https://doi.org/10.1038/s41586-021-03710-0Deposited data# 65,309 cells

Early infection response of the first trimester human placenta at single-cell scale

https://doi.org/10.1101/2023.01.02.522155Deposited data# 158,978 cells

Early role for a Na+,K+-ATPase (ATP1A3) in brain development

https://doi.org/10.1073/pnas.2023333118Deposited data# 170,525 cells

Follicular Lymphoma Microenvironment Characteristics Associated with Tumor Cell Mutations and MHC Class II Expression

https://doi.org/10.1158/2643-3230.BCD-21-0075Deposited data# 137,147 cells

Generation of complex human induced pluripotent stem cell-derived bone marrow organoids

https://doi.org/10.1038/s41592-024-02172-2Deposited data# 31,040 cells

HCA kidney seed network: University of Michigan

https://explore.data.humancellatlas.org/projects/29ed827b-c539-4f4c-bb6b-ce8f9173dfb7Deposited data# 48,783 cells

Human photoreceptor cells from different macular subregions have distinct transcriptional profiles

https://doi.org/10.1093/hmg/ddab140Deposited data# 34,323 cells

Human uterine natural killer cells regulate differentiation of extravillous trophoblast early in pregnancy

https://doi.org/10.1016/j.stem.2023.12.013Deposited data# 67,996 cells

Identification of distinct tumor cell populations and key genetic mechanisms through single cell sequencing in hepatoblastoma

https://doi.org/10.1038/s42003-021-02562-8Deposited data# 67,110 cells

Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons in development of severe COVID-19

https://doi.org/10.1126/sciimmunol.abd1554Deposited data# 59,572 cells

Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19

https://doi.org/10.1016/j.cell.2021.07.023Deposited data# 32,588 cells

Insulin is expressed by enteroendocrine cells during human fetal development

https://doi.org/10.1038/s41591-021-01586-1Deposited data# 36,359 cells

Integrated analysis of multimodal single-cell data

https://doi.org/10.1016/j.cell.2021.04.048Deposited data# 161,764 cells

Integrated analysis of multimodal single-cell data (version 2)

https://doi.org/10.1016/j.cell.2021.04.048Deposited data# 584,884 cells

Integrated multi-omics single cell atlas of the human retina

https://doi.org/10.1101/2023.11.07.566105Deposited data# 265,767 cells

Integrated scRNA-Seq Identifies Human Postnatal Thymus Seeding Progenitors and Regulatory Dynamics of Differentiating Immature Thymocytes

https://doi.org/10.1016/j.immuni.2020.03.019Deposited data# 71,732 cells

Integration of eQTL and a Single-Cell Atlas in the Human Eye Identifies Causal Genes for Age-Related Macular Degeneration

https://doi.org/10.1016/j.celrep.2019.12.082Deposited data# 100,055 cells

Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis

https://doi.org/10.1016/j.cell.2019.06.029Deposited data# 34,772 cells

Intratumoral heterogeneity in recurrent pediatric pilocytic astrocytomas

https://explore.data.humancellatlas.org/projects/575c0ad9-c78e-469b-9fdf-9a68dd881137Deposited data# 35,637 cells

Local and systemic responses to SARS-CoV-2 infection in children and adults

https://doi.org/10.1038/s41586-021-04345-xDeposited data# 659,197 cells

Longitudinal profiling of respiratory and systemic immune responses reveals myeloid cell-driven lung inflammation in severe COVID-19

https://doi.org/10.1016/j.immuni.2021.03.005Deposited data# 126,564 cells

Mapping single-cell transcriptomes in the intra-tumoral and associated territories of kidney cancer

https://doi.org/10.1016/j.ccell.2022.11.001Deposited data# 270,855 cells

Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro

https://doi.org/10.1038/s41588-021-00972-2Deposited data# 218,979 cells

Mapping the transcriptional landscape of human white and brown adipogenesis using single-nuclei RNA-seq

https://doi.org/10.1016/j.molmet.2023.101746Deposited data# 32,933 cells

Molecular characterization of selectively vulnerable neurons in Alzheimer's Disease

https://doi.org/10.1038/s41593-020-00764-7Deposited data# 106,136 cells

Molecular signatures underlying neurofibrillary tangle susceptibility in Alzheimer’s disease

https://doi.org/10.1016/j.neuron.2022.06.021Deposited data# 119,326 cells

Multi-omic profiling of the developing human cerebral cortex at the single cell level

https://doi.org/10.1126/sciadv.adg3754Deposited data# 45,549 cells

Multi-scale spatial mapping of cell populations across anatomical sites in healthy human skin and basal cell carcinoma

https://doi.org/10.1073%2Fpnas.2313326120Deposited data# 152,189 cells

Multimodal single cell sequencing implicates chromatin accessibility and genetic background in diabetic kidney disease progression

https://doi.org/10.1038/s41467-022-32972-zDeposited data# 39,176 cells

Multiomic Profiling of Human Clonal Hematopoiesis Reveals Genotype and Cell-Specific Inflammatory Pathway Activation

https://doi.org/10.1182/bloodadvances.2023011445Deposited data# 66,985 cells

Ovarian cancer mutational processes drive site-specific immune evasion

https://doi.org/10.1038/s41586-022-05496-1Deposited data# 623,859 cells

Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies

https://doi.org/10.1126/science.abo1984Deposited data# 826,733 cells

Polybacterial intracellular coinfection of epithelial stem cells in periodontitis

https://doi.org/10.1101/2023.08.23.554343Deposited data# 105,918 cells

Prolonged cytopenia following CD19 CAR T cell therapy is linked with bone marrow infiltration of clonally expanded IFNγ-expressing CD8 T cells

https://doi.org/10.1016/j.xcrm.2023.101158Deposited data# 92,676 cells

Protracted neuronal recruitment in the temporal lobes of young children

https://doi.org/10.1038/s41586-023-06981-xDeposited data# 153,005 cells

Resolving cellular and molecular diversity along the hippocampal anterior-to-posterior axis in humans

https://doi.org/10.1016/j.neuron.2021.05.003Deposited data# 129,905 cells

SARS‐CoV‐2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells

https://doi.org/10.15252/embj.20105114Deposited data# 57,229 cells

Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer

https://doi.org/10.1016/j.ccell.2021.09.008Deposited data# 147,137 cells

Single Cell Multiome Atlas of the Human Developing Retina

https://doi.org/10.21203/rs.3.rs-3417373/v1Deposited data# 226,506 cells

Single cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populations

https://doi.org/10.1038/s41467-018-06318-7Deposited data# 8,444 cells

Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease

https://doi.org/10.1038/s41467-020-19737-2Deposited data# 16,245 cells

Single cell analysis of mouse and human prostate reveals novel fibroblasts with specialized distribution and microenvironment interactions

https://doi.org/10.1002/path.5751Deposited data# 83,451 cells

Single cell derived mRNA signals across human kidney tumors

https://doi.org/10.1038/s41467-021-23949-5Deposited data# 31,839 cells

Single cell dissection of plasma cell heterogeneity in symptomatic and asymptomatic myeloma

https://doi.org/10.1038/s41591-018-0269-2Deposited data# 54,753 cells

Single cell profiling of COVID-19 patients: an international data resource from multiple tissues

https://doi.org/10.1101/2020.11.20.20227355Deposited data# 59,506 cells

Single cell profiling of COVID-19 patients: an international data resource from multiple tissues

https://doi.org/10.1101/2020.11.20.20227355Deposited data# 97,499 cells

Single cell transcriptional and chromatin accessibility profiling redefine cellular heterogeneity in the adult human kidney

https://doi.org/10.1038/s41467-021-22368-wDeposited data# 19,985 cells

Single cell transcriptomic profiling identifies molecular phenotypes of newborn human lung cells

https://doi.org/10.3390/genes15030298Deposited data# 5,499 cells

Single nuclei transcriptomics in human and non-human primate striatum in opioid use disorder

https://doi.org/10.1038/s41467-024-45165-7Deposited data# 98,848 cells

Single-Cell Analysis of Crohn’s Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy

https://doi.org/10.1016/j.cell.2019.08.008Deposited data# 32,458 cells

Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns

https://doi.org/10.1016/j.cell.2017.09.004Deposited data# 2,544 cells

Single-Cell RNA-Seq Analysis of Infiltrating Neoplastic Cells at the Migrating Front of Human Glioblastoma

https://doi.org/10.1016/j.celrep.2017.10.030Deposited data# 3,589 cells

Single-Cell Sequencing of Developing Human Gut Reveals Transcriptional Links to Childhood Crohn’s Disease

https://doi.org/10.1016/j.devcel.2020.11.010Deposited data# 85,351 cells

Single-Cell, Single-Nucleus, and Spatial RNA Sequencing of the Human Liver Identifies Cholangiocyte and Mesenchymal Heterogeneity

https://doi.org/10.1002/hep4.1854Deposited data# 73,295 cells

Single-cell Atlas of common variable immunodeficiency shows germinal center-associated epigenetic dysregulation in B-cell responses

https://doi.org/10.1038/s41467-022-29450-xDeposited data# 113,289 cells

Single-cell RNA sequencing unifies developmental programs of Esophageal and Gastric Intestinal Metaplasia

https://doi.org/10.1158/2159-8290.CD-22-0824Deposited data# 293,823 cells

Single-cell analyses of renal cell cancers reveal insights into tumor microenvironment, cell of origin, and therapy response

https://doi.org/10.1073/pnas.2103240118Deposited data# 29,129 cells

Single-cell analysis of human B cell maturation predicts how antibody class switching shapes selection dynamics

https://doi.org/10.1126/sciimmunol.abe6291Deposited data# 32,607 cells

Single-cell analysis of prenatal and postnatal human cortical development

https://doi.org/10.1126/science.adf0834Deposited data# 709,372 cells

Single-cell genomic profiling of human dopamine neurons identifies a population that selectively degenerates in Parkinson’s disease

https://doi.org/10.1038/s41593-022-01061-1Deposited data# 572,156 cells

Single-cell longitudinal analysis of SARS-CoV-2 infection in human bronchial epithelial cells

https://doi.org/10.1371/journal.pbio.3001143Deposited data# 77,650 cells

Single-cell multi-omics analysis of human pancreatic islets reveals novel cellular states in type 1 diabetes

https://doi.org/10.1038/s42255-022-00531-xDeposited data# 69,645 cells

Single-cell multi-omics analysis of the immune response in COVID-19

https://doi.org/10.1038/s41591-021-01329-2Deposited data# 647,366 cells

Single-cell multiome of the human retina and deep learning nominate causal variants in complex eye diseases

https://doi.org/10.1016/j.xgen.2022.100164Deposited data# 51,645 cells

Single-cell multiomic profiling of human lungs reveals cell-type-specific and age-dynamic control of SARS-CoV2 host genes

https://doi.org/10.7554/eLife.62522Deposited data# 46,500 cells

Single-cell multiomics reveals increased plasticity, resistant populations, and stem-cell–like blasts in KMT2A-rearranged leukemia

https://doi.org/10.1182/blood.2021013442Deposited data# 128,588 cells

Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states

https://doi.org/10.1038/s41590-021-01059-0Deposited data# 109,310 cells

Single-cell reconstruction of follicular remodeling in the human adult ovary

https://doi.org/10.1038/s41467-019-11036-9Deposited data# 20,676 cells

Single-cell reconstruction of the early maternal–fetal interface in humans

https://doi.org/10.1038/s41586-018-0698-6Deposited data# 70,325 cells

Single-cell sequencing links multiregional immune landscapes and tissue-resident T cells in ccRCC to tumor topology and therapy efficacy

https://doi.org/10.1016/j.ccell.2021.03.007Deposited data# 167,283 cells

Single-cell transcriptome analysis reveals differential nutrient absorption functions in human intestine

https://doi.org/10.1084/jem.20191130Deposited data# 14,106 cells

Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors

https://doi.org/10.1126/science.aat1699Deposited data# 40,268 cells

Single-cell transcriptomes of the human skin reveal age-related loss of fibroblast priming

https://doi.org/10.1038/s42003-020-0922-4Deposited data# 15,457 cells

Single-cell transcriptomic atlas of the human retina identifies cell types associated with age-related macular degeneration

https://doi.org/10.1038/s41467-019-12780-8Deposited data# 20,091 cells

Single-cell transcriptomics of human T cells reveals tissue and activation signatures in health and disease

https://doi.org/10.1038/s41467-019-12464-3Deposited data# 51,876 cells

Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration

https://doi.org/10.1073/pnas.1914143116Deposited data# 4,335 cells

Single-cell, single-nucleus, and spatial transcriptomics characterization of the immunological landscape in the healthy and PSC human liver

https://doi.org/10.1016/j.jhep.2023.12.023Deposited data# 195,417 cells

Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function

https://doi.org/10.1126/science.abl4290Deposited data# 209,126 cells

Spatial and cell type transcriptional landscape of human cerebellar development

https://doi.org/10.1038/s41593-021-00872-yDeposited data# 69,174 cells

Spatial multi-omic map of human myocardial infarction

https://doi.org/10.1038/s41586-022-05060-xDeposited data# 191,795 cells

Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches

https://doi.org/10.1016/j.cell.2021.12.018Deposited data# 167,598 cells

Spatially resolved multiomics of human cardiac niches

https://doi.org/10.1038/s41586-023-06311-1Deposited data# 704,296 cells

Spatiotemporal analysis of human intestinal development at single-cell resolution

https://doi.org/10.1016/j.cell.2020.12.016Deposited data# 76,592 cells

Spatiotemporal immune zonation of the human kidney

https://doi.org/10.1126/science.aat5031Deposited data# 67,465 cells

The landscape of immune dysregulation in Crohn’s disease revealed through single-cell transcriptomic profiling in the ileum and colon

https://doi.org/10.1016/j.immuni.2023.01.002Deposited data# 720,633 cells

Time-resolved Systems Immunology Reveals a Late Juncture Linked to Fatal COVID-19

https://doi.org/10.1016/j.cell.2021.02.018Deposited data# 372,081 cells

Transcriptional Programming of Normal and Inflamed Human Epidermis at Single-Cell Resolution

https://doi.org/10.1016/j.celrep.2018.09.006Deposited data# 68,036 cells

Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19

https://doi.org/10.1126/scitranslmed.abh2624Deposited data# 600,929 cells

Urethral luminal epithelia are castration-insensitive cells of the proximal prostate

https://doi.org/10.1002/pros.24020Deposited data# 28,847 cells

mRNA COVID-19 vaccine elicits potent adaptive immune response without the acute inflammation of SARS-CoV-2 infection

https://doi.org/10.1016/j.isci.2023.108572Deposited data# 195,632 cells

scRNA-seq assessment of the human lung, spleen, and esophagus tissue stability after cold preservation

https://doi.org/10.1186/s13059-019-1906-xDeposited data# 239,222 cells