Insufficient scRNA-seq data for expression of ZNF653 at single-cell level.
Insufficient scRNA-seq data for expression of ZNF653 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 968.98 | 2638 / 2642 | 100% | 9.69 | 705 / 705 |
| thymus | 100% | 741.15 | 653 / 653 | 100% | 8.24 | 603 / 605 |
| uterus | 100% | 578.78 | 170 / 170 | 100% | 7.24 | 457 / 459 |
| prostate | 100% | 705.50 | 245 / 245 | 99% | 8.41 | 499 / 502 |
| ovary | 100% | 485.56 | 180 / 180 | 99% | 8.35 | 427 / 430 |
| intestine | 100% | 514.82 | 966 / 966 | 99% | 5.77 | 522 / 527 |
| adrenal gland | 100% | 539.09 | 258 / 258 | 99% | 8.59 | 227 / 230 |
| esophagus | 100% | 464.40 | 1441 / 1445 | 99% | 5.22 | 181 / 183 |
| bladder | 100% | 499.71 | 21 / 21 | 98% | 6.36 | 492 / 504 |
| stomach | 100% | 440.52 | 358 / 359 | 98% | 5.29 | 279 / 286 |
| pancreas | 99% | 305.13 | 325 / 328 | 98% | 6.55 | 174 / 178 |
| skin | 99% | 458.41 | 1797 / 1809 | 97% | 5.28 | 460 / 472 |
| kidney | 100% | 548.34 | 89 / 89 | 96% | 5.43 | 868 / 901 |
| breast | 100% | 448.31 | 458 / 459 | 96% | 5.60 | 1076 / 1118 |
| lung | 99% | 396.33 | 571 / 578 | 95% | 4.67 | 1097 / 1155 |
| liver | 100% | 322.44 | 226 / 226 | 92% | 4.14 | 374 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 8.02 | 29 / 29 |
| spleen | 100% | 462.95 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 6.25 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 4.51 | 1 / 1 |
| blood vessel | 100% | 552.29 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 100% | 356.65 | 1198 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 4.58 | 79 / 80 |
| peripheral blood | 98% | 355.11 | 908 / 929 | 0% | 0 | 0 / 0 |
| muscle | 96% | 322.93 | 774 / 803 | 0% | 0 | 0 / 0 |
| heart | 95% | 214.04 | 815 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_1900116 | Biological process | extracellular negative regulation of signal transduction |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005634 | Cellular component | nucleus |
| GO_0003677 | Molecular function | DNA binding |
| GO_0050682 | Molecular function | AF-2 domain binding |
| GO_0140297 | Molecular function | DNA-binding transcription factor binding |
| GO_0003714 | Molecular function | transcription corepressor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0003712 | Molecular function | transcription coregulator activity |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | ZNF653 |
| Protein name | Zinc finger protein 653 Zinc finger protein 653 (67 kDa zinc finger protein) (Zinc finger protein Zip67) |
| Synonyms | ZIP67 |
| Description | FUNCTION: Transcriptional repressor. May repress NR5A1, PPARG, NR1H3, NR4A2, ESR1 and NR3C1 transcriptional activity. . |
| Accessions | ENST00000592756.1 K7ENS4 ENST00000590296.5 Q96CK0 ENST00000293771.10 ENST00000589051.1 ENST00000588541.5 K7EL79 K7EJG9 K7EKL4 |