ZBTB32 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ZBTB32 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ZBTB32 at tissue level.

III. Associated gene sets

GO_0002682Biological processregulation of immune system process
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0001817Biological processregulation of cytokine production
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameZBTB32
Protein nameZinc finger and BTB domain-containing protein 32 (FANCC-interacting protein) (Fanconi anemia zinc finger protein) (Testis zinc finger protein) (Zinc finger protein 538)
Zinc finger and BTB domain containing 32 isoform 1
Zinc finger and BTB domain containing 32
Zinc finger and BTB domain containing 32 isoform 2
SynonymsZNF538
TZFP
FAZF
DescriptionFUNCTION: DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells (By similarity). .

AccessionsENST00000426659.6
K7EMJ1
A0A0S2Z5S3
ENST00000481182.1
A0A0S2Z564
ENST00000392197.7
A0A0C4DGF1
ENST00000262630.7
Q9Y2Y4