YEATS2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0045995Biological processregulation of embryonic development
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0090043Biological processregulation of tubulin deacetylation
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0006338Biological processchromatin remodeling
GO_0051302Biological processregulation of cell division
GO_0006355Biological processregulation of DNA-templated transcription
GO_0051726Biological processregulation of cell cycle
GO_0072686Cellular componentmitotic spindle
GO_0005654Cellular componentnucleoplasm
GO_0035267Cellular componentNuA4 histone acetyltransferase complex
GO_0140672Cellular componentATAC complex
GO_0005634Cellular componentnucleus
GO_0017025Molecular functionTBP-class protein binding
GO_0042393Molecular functionhistone binding
GO_0003714Molecular functiontranscription corepressor activity
GO_0140566Molecular functionhistone reader activity
GO_0140030Molecular functionmodification-dependent protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameYEATS2
Protein nameYEATS2 protein
YEATS domain-containing protein 2
YEATS domain containing 2
SynonymsKIAA1197
DescriptionFUNCTION: Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 . YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr) . Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors . .

AccessionsENST00000432781.1
H0Y6M6
Q8N5H6
ENST00000305135.10
Q9ULM3