Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 14 studies | 31% ± 17% | |
astrocyte | 11 studies | 30% ± 12% | |
macrophage | 10 studies | 28% ± 14% | |
oligodendrocyte precursor cell | 10 studies | 35% ± 15% | |
oligodendrocyte | 10 studies | 30% ± 10% | |
glutamatergic neuron | 9 studies | 50% ± 24% | |
microglial cell | 8 studies | 28% ± 11% | |
GABAergic neuron | 7 studies | 47% ± 19% | |
epithelial cell | 6 studies | 20% ± 6% | |
interneuron | 6 studies | 45% ± 20% | |
neuron | 5 studies | 42% ± 13% | |
fibroblast | 5 studies | 24% ± 10% | |
type I pneumocyte | 5 studies | 36% ± 11% | |
pericyte | 4 studies | 31% ± 16% | |
amacrine cell | 4 studies | 19% ± 6% | |
endothelial cell of lymphatic vessel | 4 studies | 25% ± 3% | |
GABAergic interneuron | 3 studies | 33% ± 12% | |
granule cell | 3 studies | 29% ± 1% | |
retina horizontal cell | 3 studies | 24% ± 7% | |
retinal ganglion cell | 3 studies | 28% ± 6% | |
retinal rod cell | 3 studies | 28% ± 3% | |
abnormal cell | 3 studies | 23% ± 10% | |
alveolar macrophage | 3 studies | 22% ± 6% | |
smooth muscle cell | 3 studies | 17% ± 1% | |
lymphocyte | 3 studies | 24% ± 8% | |
myeloid cell | 3 studies | 27% ± 2% | |
dendritic cell | 3 studies | 19% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 2497.06 | 1445 / 1445 | 100% | 32.04 | 183 / 183 |
brain | 100% | 3039.81 | 2639 / 2642 | 100% | 22.83 | 705 / 705 |
ovary | 100% | 3628.83 | 180 / 180 | 100% | 21.99 | 428 / 430 |
lung | 100% | 3022.80 | 578 / 578 | 99% | 28.36 | 1147 / 1155 |
breast | 100% | 2204.35 | 459 / 459 | 99% | 16.77 | 1107 / 1118 |
bladder | 100% | 2758.24 | 21 / 21 | 99% | 17.55 | 499 / 504 |
uterus | 100% | 2950.65 | 170 / 170 | 99% | 25.14 | 453 / 459 |
intestine | 100% | 2379.58 | 966 / 966 | 99% | 14.32 | 520 / 527 |
prostate | 100% | 2842.67 | 245 / 245 | 98% | 13.94 | 494 / 502 |
stomach | 100% | 1395.17 | 358 / 359 | 99% | 15.61 | 282 / 286 |
thymus | 100% | 3228.37 | 653 / 653 | 98% | 14.00 | 594 / 605 |
skin | 100% | 2977.93 | 1808 / 1809 | 97% | 20.45 | 460 / 472 |
pancreas | 96% | 964.99 | 315 / 328 | 98% | 13.25 | 175 / 178 |
kidney | 100% | 1869.69 | 89 / 89 | 93% | 14.53 | 839 / 901 |
adrenal gland | 100% | 1366.30 | 258 / 258 | 81% | 7.39 | 187 / 230 |
liver | 82% | 629.70 | 185 / 226 | 48% | 4.10 | 193 / 406 |
adipose | 100% | 2173.21 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 20.61 | 29 / 29 |
spleen | 100% | 2409.25 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 28.78 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 5.55 | 1 / 1 |
blood vessel | 100% | 2151.85 | 1333 / 1335 | 0% | 0 | 0 / 0 |
heart | 98% | 1306.74 | 843 / 861 | 0% | 0 | 0 / 0 |
muscle | 90% | 795.41 | 721 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 87% | 2064.29 | 810 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 71% | 6.09 | 57 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0045995 | Biological process | regulation of embryonic development |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0090043 | Biological process | regulation of tubulin deacetylation |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0006338 | Biological process | chromatin remodeling |
GO_0051302 | Biological process | regulation of cell division |
GO_0006355 | Biological process | regulation of DNA-templated transcription |
GO_0051726 | Biological process | regulation of cell cycle |
GO_0072686 | Cellular component | mitotic spindle |
GO_0005654 | Cellular component | nucleoplasm |
GO_0035267 | Cellular component | NuA4 histone acetyltransferase complex |
GO_0140672 | Cellular component | ATAC complex |
GO_0005634 | Cellular component | nucleus |
GO_0017025 | Molecular function | TBP-class protein binding |
GO_0042393 | Molecular function | histone binding |
GO_0003714 | Molecular function | transcription corepressor activity |
GO_0140566 | Molecular function | histone reader activity |
GO_0140030 | Molecular function | modification-dependent protein binding |
GO_0005515 | Molecular function | protein binding |
Gene name | YEATS2 |
Protein name | YEATS2 protein YEATS domain-containing protein 2 YEATS domain containing 2 |
Synonyms | KIAA1197 |
Description | FUNCTION: Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 . YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr) . Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors . . |
Accessions | ENST00000432781.1 H0Y6M6 Q8N5H6 ENST00000305135.10 Q9ULM3 |