Insufficient scRNA-seq data for expression of XCR1 at single-cell level.
Insufficient scRNA-seq data for expression of XCR1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 71% | 59.77 | 410 / 578 | 41% | 1.06 | 472 / 1155 |
| skin | 71% | 358.46 | 1291 / 1809 | 36% | 1.15 | 168 / 472 |
| spleen | 96% | 287.01 | 231 / 241 | 0% | 0 | 0 / 0 |
| bladder | 62% | 33.90 | 13 / 21 | 26% | 1.20 | 129 / 504 |
| lymph node | 0% | 0 | 0 / 0 | 79% | 7.47 | 23 / 29 |
| esophagus | 40% | 28.74 | 575 / 1445 | 31% | 0.69 | 56 / 183 |
| stomach | 39% | 17.94 | 139 / 359 | 30% | 1.29 | 86 / 286 |
| intestine | 45% | 48.61 | 430 / 966 | 18% | 0.53 | 96 / 527 |
| tonsil | 0% | 0 | 0 / 0 | 62% | 1.85 | 28 / 45 |
| thymus | 33% | 20.18 | 215 / 653 | 25% | 0.99 | 152 / 605 |
| breast | 25% | 10.72 | 113 / 459 | 32% | 0.75 | 354 / 1118 |
| peripheral blood | 48% | 50.04 | 445 / 929 | 0% | 0 | 0 / 0 |
| kidney | 11% | 10.37 | 10 / 89 | 33% | 1.06 | 300 / 901 |
| pancreas | 4% | 0.93 | 12 / 328 | 37% | 1.04 | 66 / 178 |
| uterus | 12% | 5.28 | 21 / 170 | 18% | 0.50 | 83 / 459 |
| adipose | 28% | 12.23 | 338 / 1204 | 0% | 0 | 0 / 0 |
| prostate | 9% | 3.82 | 23 / 245 | 13% | 0.24 | 65 / 502 |
| ovary | 9% | 3.14 | 17 / 180 | 8% | 0.13 | 34 / 430 |
| liver | 6% | 2.67 | 14 / 226 | 9% | 0.20 | 36 / 406 |
| blood vessel | 10% | 5.42 | 129 / 1335 | 0% | 0 | 0 / 0 |
| adrenal gland | 6% | 2.28 | 16 / 258 | 2% | 0.03 | 4 / 230 |
| eye | 0% | 0 | 0 / 0 | 8% | 0.13 | 6 / 80 |
| muscle | 7% | 2.14 | 55 / 803 | 0% | 0 | 0 / 0 |
| heart | 3% | 0.87 | 25 / 861 | 0% | 0 | 0 / 0 |
| brain | 0% | 0.07 | 6 / 2642 | 1% | 0.04 | 10 / 705 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006955 | Biological process | immune response |
| GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
| GO_0070098 | Biological process | chemokine-mediated signaling pathway |
| GO_0007204 | Biological process | positive regulation of cytosolic calcium ion concentration |
| GO_0006954 | Biological process | inflammatory response |
| GO_0006935 | Biological process | chemotaxis |
| GO_0051209 | Biological process | release of sequestered calcium ion into cytosol |
| GO_0019722 | Biological process | calcium-mediated signaling |
| GO_0060326 | Biological process | cell chemotaxis |
| GO_0007187 | Biological process | G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger |
| GO_0009897 | Cellular component | external side of plasma membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016493 | Molecular function | C-C chemokine receptor activity |
| GO_0019957 | Molecular function | C-C chemokine binding |
| GO_0004950 | Molecular function | chemokine receptor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | XCR1 |
| Protein name | Chemokine XC receptor 1 (G-protein coupled receptor 5) (Lymphotactin receptor) (XC chemokine receptor 1) Chemokine (C motif) receptor 1 Chemokine C motif receptor 1 (X-C motif chemokine receptor 1) |
| Synonyms | CCXCR1 GPR5 |
| Description | FUNCTION: Receptor for chemokines SCYC1 and SCYC2. Subsequently transduces a signal by increasing the intracellular calcium ions level. Receptor for XCL1/Lymphotactin. . |
| Accessions | ENST00000683768.1 Q502V0 ENST00000309285.4 Q689E2 P46094 ENST00000395946.3 |