Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell of lymphatic vessel | 20 studies | 44% ± 17% | |
endothelial cell | 18 studies | 38% ± 22% | |
astrocyte | 16 studies | 39% ± 14% | |
oligodendrocyte | 15 studies | 59% ± 13% | |
glutamatergic neuron | 13 studies | 63% ± 24% | |
regulatory T cell | 13 studies | 23% ± 9% | |
GABAergic neuron | 10 studies | 55% ± 20% | |
oligodendrocyte precursor cell | 9 studies | 31% ± 6% | |
neuron | 8 studies | 47% ± 20% | |
retinal ganglion cell | 7 studies | 45% ± 17% | |
epithelial cell | 6 studies | 32% ± 17% | |
interneuron | 6 studies | 63% ± 13% | |
microglial cell | 6 studies | 32% ± 19% | |
retina horizontal cell | 6 studies | 34% ± 13% | |
retinal cone cell | 6 studies | 33% ± 15% | |
T cell | 6 studies | 25% ± 5% | |
erythrocyte | 6 studies | 46% ± 26% | |
retinal bipolar neuron | 5 studies | 25% ± 6% | |
retinal rod cell | 5 studies | 35% ± 8% | |
CD8-positive, alpha-beta T cell | 5 studies | 23% ± 6% | |
lymphocyte | 5 studies | 30% ± 9% | |
natural killer cell | 5 studies | 21% ± 4% | |
abnormal cell | 4 studies | 24% ± 10% | |
granule cell | 4 studies | 64% ± 13% | |
amacrine cell | 4 studies | 45% ± 12% | |
retinal pigment epithelial cell | 4 studies | 40% ± 16% | |
effector memory CD8-positive, alpha-beta T cell | 4 studies | 24% ± 8% | |
OFF-bipolar cell | 4 studies | 30% ± 13% | |
ON-bipolar cell | 4 studies | 30% ± 10% | |
gamma-delta T cell | 4 studies | 17% ± 1% | |
smooth muscle cell | 3 studies | 37% ± 13% | |
pericyte | 3 studies | 34% ± 19% | |
GABAergic interneuron | 3 studies | 48% ± 9% | |
glial cell | 3 studies | 38% ± 13% | |
macrophage | 3 studies | 34% ± 23% | |
connective tissue cell | 3 studies | 33% ± 15% | |
capillary endothelial cell | 3 studies | 37% ± 13% | |
CD4-positive, alpha-beta T cell | 3 studies | 31% ± 6% | |
mesothelial cell | 3 studies | 30% ± 6% | |
GABAergic amacrine cell | 3 studies | 41% ± 7% | |
glycinergic amacrine cell | 3 studies | 49% ± 5% | |
rod bipolar cell | 3 studies | 65% ± 14% | |
luminal hormone-sensing cell of mammary gland | 3 studies | 26% ± 6% | |
ependymal cell | 3 studies | 47% ± 13% | |
myofibroblast cell | 3 studies | 22% ± 3% | |
fibroblast | 3 studies | 27% ± 8% | |
type I pneumocyte | 3 studies | 24% ± 4% | |
basal cell | 3 studies | 32% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 5697.51 | 2642 / 2642 | 100% | 44.01 | 703 / 705 |
thymus | 99% | 1946.01 | 649 / 653 | 88% | 11.13 | 531 / 605 |
uterus | 98% | 3402.05 | 167 / 170 | 84% | 13.57 | 384 / 459 |
prostate | 94% | 1005.94 | 231 / 245 | 82% | 7.41 | 410 / 502 |
bladder | 90% | 1020.14 | 19 / 21 | 77% | 10.63 | 386 / 504 |
esophagus | 94% | 1302.12 | 1363 / 1445 | 72% | 8.67 | 132 / 183 |
intestine | 78% | 944.85 | 758 / 966 | 79% | 9.61 | 415 / 527 |
lung | 61% | 490.73 | 355 / 578 | 86% | 13.74 | 997 / 1155 |
skin | 100% | 3882.76 | 1805 / 1809 | 42% | 8.45 | 197 / 472 |
breast | 56% | 938.35 | 257 / 459 | 84% | 19.20 | 941 / 1118 |
ovary | 100% | 5486.18 | 180 / 180 | 29% | 2.28 | 126 / 430 |
kidney | 74% | 577.35 | 66 / 89 | 54% | 11.56 | 487 / 901 |
stomach | 65% | 744.06 | 235 / 359 | 62% | 7.33 | 178 / 286 |
spleen | 100% | 1789.91 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 4.75 | 1 / 1 |
tonsil | 0% | 0 | 0 / 0 | 96% | 15.24 | 43 / 45 |
pancreas | 0% | 2.60 | 1 / 328 | 83% | 9.32 | 148 / 178 |
peripheral blood | 71% | 1145.01 | 661 / 929 | 0% | 0 | 0 / 0 |
adrenal gland | 1% | 20.86 | 2 / 258 | 63% | 6.08 | 146 / 230 |
blood vessel | 56% | 500.86 | 750 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 55% | 4.47 | 16 / 29 |
adipose | 41% | 352.21 | 490 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 38% | 2.97 | 30 / 80 |
muscle | 29% | 389.10 | 235 / 803 | 0% | 0 | 0 / 0 |
liver | 0% | 2.23 | 1 / 226 | 17% | 3.31 | 68 / 406 |
heart | 8% | 59.03 | 65 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0045747 | Biological process | positive regulation of Notch signaling pathway |
GO_0072659 | Biological process | protein localization to plasma membrane |
GO_0051043 | Biological process | regulation of membrane protein ectodomain proteolysis |
GO_0051604 | Biological process | protein maturation |
GO_0015629 | Cellular component | actin cytoskeleton |
GO_0005788 | Cellular component | endoplasmic reticulum lumen |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005886 | Cellular component | plasma membrane |
GO_0019899 | Molecular function | enzyme binding |
GO_0005515 | Molecular function | protein binding |
Gene name | TSPAN5 |
Protein name | Tetraspanin-5 (Tspan-5) (Tetraspan NET-4) (Transmembrane 4 superfamily member 9) Tetraspanin Tetraspanin 5 |
Synonyms | TM4SF9 |
Description | FUNCTION: Part of TspanC8 subgroup, composed of 6 members that interact with the transmembrane metalloprotease ADAM10. This interaction is required for ADAM10 exit from the endoplasmic reticulum and for enzymatic maturation and trafficking to the cell surface as well as substrate specificity. Different TspanC8/ADAM10 complexes have distinct substrates . Promotes ADAM10-mediated cleavage of CD44 . Seems to regulate VE-cadherin expression in endothelial cells probably through interaction with ADAM10, promoting leukocyte transmigration . . |
Accessions | D6RGZ7 ENST00000508798.5 D6RAR1 D6RBT5 ENST00000305798.8 ENST00000515440.5 ENST00000511800.5 B7Z317 ENST00000511651.5 ENST00000515287.5 ENST00000505184.5 D6R9N6 P62079 H0Y8W4 |