TRIM2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0000209Biological processprotein polyubiquitination
GO_0043523Biological processregulation of neuron apoptotic process
GO_0043161Biological processproteasome-mediated ubiquitin-dependent protein catabolic process
GO_0017148Biological processnegative regulation of translation
GO_0005737Cellular componentcytoplasm
GO_0061630Molecular functionubiquitin protein ligase activity
GO_0030371Molecular functiontranslation repressor activity
GO_0004842Molecular functionubiquitin-protein transferase activity
GO_0005515Molecular functionprotein binding
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameTRIM2
Protein nameTripartite motif-containing protein 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM2) (RING finger protein 86) (RING-type E3 ubiquitin transferase TRIM2)
RING-type E3 ubiquitin transferase (EC 2.3.2.27)
Tripartite motif containing 2
Tripartite motif-containing protein 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM2) (RING-type E3 ubiquitin transferase TRIM2)
SynonymsKIAA0517
RNF86
DescriptionFUNCTION: UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance. Plays a role in antiviral immunity and limits New World arenavirus infection independently of its ubiquitin ligase activity . .

AccessionsA0A6Q8PGS7
A0A6Q8PFV0
A0A6Q8PG80
A0A6Q8PF74
A0A6Q8PEY9
ENST00000494872.6
ENST00000675456.1
A0A6Q8PHE9
ENST00000675343.1
ENST00000675425.1
ENST00000675782.1
ENST00000675159.1 [Q9C040-1]
A0A6Q8PHP4
ENST00000675063.1
ENST00000675673.1
A0A6Q8PFS5
A0A6Q8PFE3
A0A6Q8PHR6
ENST00000676335.1
ENST00000676158.1
ENST00000338700.10 [Q9C040-2]
A0A6Q8PG79
ENST00000676224.1
ENST00000502281.3
ENST00000674730.1
A0A6Q8PGW9
ENST00000675623.1
ENST00000675312.1
ENST00000674726.1
ENST00000676033.1
A0A0J9YX34
A0A0J9YW70
ENST00000675412.1
A0A6Q8PFP1
ENST00000675899.1
ENST00000676220.1
ENST00000675710.1
ENST00000675315.1 [Q9C040-1]
A0A6Q8PHB2
ENST00000674874.1 [Q9C040-1]
A0A6Q8PGM7
ENST00000675239.1
ENST00000675340.1
ENST00000675210.1
ENST00000675780.1
ENST00000675804.1
A0A6Q8PEY7
ENST00000675835.1 [Q9C040-1]
ENST00000437508.7 [Q9C040-1]
A0A6Q8PGF3
ENST00000675627.1
ENST00000482578.3
ENST00000675738.1
ENST00000675745.1 [Q9C040-1]
ENST00000676348.1 [Q9C040-1]
ENST00000676015.1
ENST00000675384.1 [Q9C040-1]
ENST00000676172.1 [Q9C040-1]
ENST00000460908.2
A0A6Q8PGE9
ENST00000675462.1
A0A6Q8PHG3
ENST00000675977.1
ENST00000674935.1
A0A6Q8PGZ0
ENST00000675567.1
Q9C040
ENST00000674876.1 [Q9C040-1]
ENST00000675744.1
ENST00000675492.1
ENST00000674832.1
A0A6Q8PGL5
ENST00000676196.1
ENST00000676167.1
A0A6Q8PFM2
ENST00000674786.1
ENST00000675611.1
A0A6Q8PG16
ENST00000675348.1
A0A6Q8PF82
ENST00000675411.1
A0A6Q8PGR7
ENST00000676374.1 [Q9C040-1]
ENST00000674769.1
ENST00000674896.1
ENST00000676029.1
A0A6Q8PFD3
C9J084
ENST00000676423.1 [Q9C040-1]
ENST00000676191.1
ENST00000675136.1
ENST00000675146.1
ENST00000675783.1
A0A6Q8PG97
ENST00000441616.6
ENST00000433687.2
A0A6Q8PGG4
A0A6Q8PFX3
ENST00000675293.1 [Q9C040-1]
ENST00000674847.1
ENST00000676291.1
ENST00000676252.1 [Q9C040-1]
A0A6Q8PH39
ENST00000676458.1 [Q9C040-1]
A0A6Q8PFI4
A0A6Q8PGK8
ENST00000674976.1 [Q9C040-1]
ENST00000675054.1 [Q9C040-1]
ENST00000632856.2
A0A6Q8PF63
A0A6Q8PFB0
ENST00000674872.1
ENST00000676408.1
ENST00000676264.1 [Q9C040-1]
A0A0J9YW02
ENST00000676202.1