Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 20 studies | 49% ± 15% | |
ciliated cell | 16 studies | 41% ± 15% | |
oligodendrocyte | 16 studies | 78% ± 14% | |
oligodendrocyte precursor cell | 15 studies | 48% ± 19% | |
glutamatergic neuron | 12 studies | 66% ± 20% | |
GABAergic neuron | 11 studies | 59% ± 21% | |
basal cell | 8 studies | 30% ± 11% | |
club cell | 8 studies | 33% ± 13% | |
epithelial cell | 8 studies | 41% ± 15% | |
kidney loop of Henle epithelial cell | 7 studies | 31% ± 6% | |
neuron | 7 studies | 54% ± 15% | |
endothelial cell | 7 studies | 38% ± 20% | |
retinal ganglion cell | 7 studies | 67% ± 21% | |
respiratory goblet cell | 6 studies | 38% ± 12% | |
renal alpha-intercalated cell | 6 studies | 36% ± 8% | |
interneuron | 6 studies | 65% ± 10% | |
retina horizontal cell | 6 studies | 34% ± 7% | |
Mueller cell | 6 studies | 42% ± 12% | |
retinal bipolar neuron | 5 studies | 38% ± 20% | |
amacrine cell | 5 studies | 38% ± 12% | |
type II pneumocyte | 5 studies | 21% ± 5% | |
goblet cell | 5 studies | 23% ± 4% | |
duct epithelial cell | 4 studies | 27% ± 13% | |
granule cell | 4 studies | 57% ± 5% | |
microglial cell | 4 studies | 34% ± 13% | |
fibroblast | 4 studies | 19% ± 4% | |
cardiac muscle cell | 4 studies | 18% ± 1% | |
OFF-bipolar cell | 4 studies | 49% ± 19% | |
ON-bipolar cell | 4 studies | 46% ± 22% | |
ionocyte | 3 studies | 35% ± 5% | |
secretory cell | 3 studies | 31% ± 5% | |
squamous epithelial cell | 3 studies | 56% ± 13% | |
differentiation-committed oligodendrocyte precursor | 3 studies | 64% ± 14% | |
GABAergic interneuron | 3 studies | 58% ± 6% | |
glial cell | 3 studies | 48% ± 17% | |
pericyte | 3 studies | 34% ± 21% | |
progenitor cell | 3 studies | 51% ± 22% | |
retinal cone cell | 3 studies | 24% ± 5% | |
serous secreting cell | 3 studies | 24% ± 3% | |
GABAergic amacrine cell | 3 studies | 34% ± 6% | |
glycinergic amacrine cell | 3 studies | 27% ± 4% | |
rod bipolar cell | 3 studies | 40% ± 6% | |
abnormal cell | 3 studies | 20% ± 3% | |
ependymal cell | 3 studies | 65% ± 15% | |
enteroendocrine cell | 3 studies | 25% ± 9% | |
intestinal crypt stem cell | 3 studies | 25% ± 6% | |
kidney distal convoluted tubule epithelial cell | 3 studies | 33% ± 4% | |
renal principal cell | 3 studies | 20% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 13094.41 | 2641 / 2642 | 100% | 32.37 | 703 / 705 |
stomach | 100% | 4737.05 | 359 / 359 | 96% | 22.59 | 274 / 286 |
intestine | 99% | 3793.38 | 958 / 966 | 96% | 24.62 | 508 / 527 |
thymus | 100% | 7160.98 | 651 / 653 | 91% | 20.23 | 551 / 605 |
adrenal gland | 99% | 2778.26 | 255 / 258 | 91% | 19.77 | 210 / 230 |
esophagus | 92% | 2032.33 | 1329 / 1445 | 93% | 23.40 | 171 / 183 |
pancreas | 96% | 2009.08 | 315 / 328 | 88% | 10.22 | 157 / 178 |
kidney | 100% | 4086.53 | 89 / 89 | 84% | 13.73 | 757 / 901 |
prostate | 99% | 3430.98 | 243 / 245 | 80% | 9.19 | 401 / 502 |
lung | 82% | 1626.51 | 473 / 578 | 93% | 18.82 | 1069 / 1155 |
skin | 85% | 1934.81 | 1541 / 1809 | 86% | 20.59 | 405 / 472 |
bladder | 95% | 3216.00 | 20 / 21 | 72% | 13.36 | 363 / 504 |
uterus | 99% | 2925.49 | 168 / 170 | 65% | 8.49 | 298 / 459 |
ovary | 100% | 2872.05 | 180 / 180 | 61% | 5.07 | 262 / 430 |
breast | 85% | 2557.75 | 391 / 459 | 56% | 6.76 | 630 / 1118 |
ureter | 0% | 0 | 0 / 0 | 100% | 8.67 | 1 / 1 |
spleen | 98% | 2398.61 | 236 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 91% | 1733.88 | 1214 / 1335 | 0% | 0 | 0 / 0 |
adipose | 83% | 1541.42 | 1001 / 1204 | 0% | 0 | 0 / 0 |
liver | 49% | 696.83 | 110 / 226 | 25% | 1.85 | 102 / 406 |
tonsil | 0% | 0 | 0 / 0 | 69% | 9.85 | 31 / 45 |
heart | 59% | 966.36 | 507 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 59% | 5.90 | 47 / 80 |
muscle | 1% | 16.64 | 11 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 1% | 9.46 | 5 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0000209 | Biological process | protein polyubiquitination |
GO_0043523 | Biological process | regulation of neuron apoptotic process |
GO_0043161 | Biological process | proteasome-mediated ubiquitin-dependent protein catabolic process |
GO_0017148 | Biological process | negative regulation of translation |
GO_0005737 | Cellular component | cytoplasm |
GO_0061630 | Molecular function | ubiquitin protein ligase activity |
GO_0030371 | Molecular function | translation repressor activity |
GO_0004842 | Molecular function | ubiquitin-protein transferase activity |
GO_0005515 | Molecular function | protein binding |
GO_0008270 | Molecular function | zinc ion binding |
Gene name | TRIM2 |
Protein name | Tripartite motif-containing protein 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM2) (RING finger protein 86) (RING-type E3 ubiquitin transferase TRIM2) RING-type E3 ubiquitin transferase (EC 2.3.2.27) Tripartite motif containing 2 Tripartite motif-containing protein 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM2) (RING-type E3 ubiquitin transferase TRIM2) |
Synonyms | KIAA0517 RNF86 |
Description | FUNCTION: UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance. Plays a role in antiviral immunity and limits New World arenavirus infection independently of its ubiquitin ligase activity . . |
Accessions | A0A6Q8PGS7 A0A6Q8PFV0 A0A6Q8PG80 A0A6Q8PF74 A0A6Q8PEY9 ENST00000494872.6 ENST00000675456.1 A0A6Q8PHE9 ENST00000675343.1 ENST00000675425.1 ENST00000675782.1 ENST00000675159.1 [Q9C040-1] A0A6Q8PHP4 ENST00000675063.1 ENST00000675673.1 A0A6Q8PFS5 A0A6Q8PFE3 A0A6Q8PHR6 ENST00000676335.1 ENST00000676158.1 ENST00000338700.10 [Q9C040-2] A0A6Q8PG79 ENST00000676224.1 ENST00000502281.3 ENST00000674730.1 A0A6Q8PGW9 ENST00000675623.1 ENST00000675312.1 ENST00000674726.1 ENST00000676033.1 A0A0J9YX34 A0A0J9YW70 ENST00000675412.1 A0A6Q8PFP1 ENST00000675899.1 ENST00000676220.1 ENST00000675710.1 ENST00000675315.1 [Q9C040-1] A0A6Q8PHB2 ENST00000674874.1 [Q9C040-1] A0A6Q8PGM7 ENST00000675239.1 ENST00000675340.1 ENST00000675210.1 ENST00000675780.1 ENST00000675804.1 A0A6Q8PEY7 ENST00000675835.1 [Q9C040-1] ENST00000437508.7 [Q9C040-1] A0A6Q8PGF3 ENST00000675627.1 ENST00000482578.3 ENST00000675738.1 ENST00000675745.1 [Q9C040-1] ENST00000676348.1 [Q9C040-1] ENST00000676015.1 ENST00000675384.1 [Q9C040-1] ENST00000676172.1 [Q9C040-1] ENST00000460908.2 A0A6Q8PGE9 ENST00000675462.1 A0A6Q8PHG3 ENST00000675977.1 ENST00000674935.1 A0A6Q8PGZ0 ENST00000675567.1 Q9C040 ENST00000674876.1 [Q9C040-1] ENST00000675744.1 ENST00000675492.1 ENST00000674832.1 A0A6Q8PGL5 ENST00000676196.1 ENST00000676167.1 A0A6Q8PFM2 ENST00000674786.1 ENST00000675611.1 A0A6Q8PG16 ENST00000675348.1 A0A6Q8PF82 ENST00000675411.1 A0A6Q8PGR7 ENST00000676374.1 [Q9C040-1] ENST00000674769.1 ENST00000674896.1 ENST00000676029.1 A0A6Q8PFD3 C9J084 ENST00000676423.1 [Q9C040-1] ENST00000676191.1 ENST00000675136.1 ENST00000675146.1 ENST00000675783.1 A0A6Q8PG97 ENST00000441616.6 ENST00000433687.2 A0A6Q8PGG4 A0A6Q8PFX3 ENST00000675293.1 [Q9C040-1] ENST00000674847.1 ENST00000676291.1 ENST00000676252.1 [Q9C040-1] A0A6Q8PH39 ENST00000676458.1 [Q9C040-1] A0A6Q8PFI4 A0A6Q8PGK8 ENST00000674976.1 [Q9C040-1] ENST00000675054.1 [Q9C040-1] ENST00000632856.2 A0A6Q8PF63 A0A6Q8PFB0 ENST00000674872.1 ENST00000676408.1 ENST00000676264.1 [Q9C040-1] A0A0J9YW02 ENST00000676202.1 |