TNRC6C | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
astrocyte	17 studies	36% ± 16%	Explore
oligodendrocyte	15 studies	48% ± 17%	Explore
oligodendrocyte precursor cell	15 studies	52% ± 21%	Explore
endothelial cell	15 studies	33% ± 15%	Explore
glutamatergic neuron	12 studies	59% ± 23%	Explore
GABAergic neuron	11 studies	51% ± 23%	Explore
fibroblast	10 studies	32% ± 15%	Explore
amacrine cell	8 studies	43% ± 14%	Explore
pericyte	8 studies	31% ± 16%	Explore
neuron	7 studies	45% ± 19%	Explore
retinal cone cell	7 studies	38% ± 16%	Explore
retinal rod cell	7 studies	33% ± 12%	Explore
adipocyte	7 studies	26% ± 7%	Explore
smooth muscle cell	7 studies	26% ± 8%	Explore
epithelial cell	6 studies	23% ± 7%	Explore
interneuron	6 studies	64% ± 21%	Explore
microglial cell	6 studies	26% ± 11%	Explore
retina horizontal cell	6 studies	29% ± 10%	Explore
retinal bipolar neuron	5 studies	36% ± 10%	Explore
CD8-positive, alpha-beta T cell	5 studies	20% ± 4%	Explore
cardiac muscle cell	5 studies	34% ± 10%	Explore
Mueller cell	5 studies	27% ± 12%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	20% ± 7%	Explore
T cell	5 studies	27% ± 6%	Explore
endothelial cell of lymphatic vessel	5 studies	21% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	26% ± 5%	Explore
granule cell	4 studies	46% ± 12%	Explore
B cell	4 studies	19% ± 4%	Explore
retinal pigment epithelial cell	4 studies	40% ± 18%	Explore
retinal ganglion cell	4 studies	34% ± 12%	Explore
CD4-positive, alpha-beta T cell	4 studies	23% ± 5%	Explore
lymphocyte	4 studies	35% ± 10%	Explore
natural killer cell	4 studies	26% ± 8%	Explore
connective tissue cell	4 studies	17% ± 2%	Explore
CD16-negative, CD56-bright natural killer cell, human	3 studies	24% ± 5%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	3 studies	23% ± 6%	Explore
GABAergic interneuron	3 studies	56% ± 2%	Explore
glial cell	3 studies	24% ± 4%	Explore
macrophage	3 studies	26% ± 8%	Explore
ciliated cell	3 studies	20% ± 2%	Explore
GABAergic amacrine cell	3 studies	61% ± 11%	Explore
OFF-bipolar cell	3 studies	46% ± 15%	Explore
ON-bipolar cell	3 studies	45% ± 14%	Explore
glycinergic amacrine cell	3 studies	65% ± 7%	Explore
rod bipolar cell	3 studies	41% ± 12%	Explore
endothelial cell of vascular tree	3 studies	24% ± 6%	Explore
neural progenitor cell	3 studies	23% ± 2%	Explore
ependymal cell	3 studies	33% ± 14%	Explore
adventitial cell	3 studies	18% ± 2%	Explore
Schwann cell	3 studies	35% ± 19%	Explore
mural cell	3 studies	35% ± 15%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	16 studies	51% ± 21%	Explore
eye	9 studies	33% ± 14%	Explore
heart	3 studies	30% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	2678.62	245 / 245	100%	9.76	502 / 502
brain	100%	3671.19	2641 / 2642	99%	20.77	699 / 705
thymus	100%	2291.14	652 / 653	99%	8.97	599 / 605
esophagus	99%	2290.14	1430 / 1445	99%	7.89	182 / 183
breast	100%	2729.37	459 / 459	98%	13.65	1099 / 1118
skin	99%	1302.30	1796 / 1809	97%	8.68	458 / 472
stomach	99%	1498.69	357 / 359	93%	6.54	265 / 286
ovary	100%	2621.58	180 / 180	92%	7.71	396 / 430
kidney	100%	1166.16	89 / 89	92%	5.26	826 / 901
lung	99%	1569.76	574 / 578	91%	5.91	1048 / 1155
pancreas	94%	800.32	308 / 328	96%	5.90	170 / 178
intestine	100%	2002.02	966 / 966	89%	4.69	470 / 527
adrenal gland	99%	1195.03	256 / 258	90%	8.88	206 / 230
uterus	100%	2926.91	170 / 170	80%	4.80	369 / 459
bladder	100%	2198.10	21 / 21	77%	3.62	386 / 504
liver	99%	882.47	223 / 226	68%	2.95	276 / 406
adipose	100%	2465.99	1204 / 1204	0%	0	0 / 0
blood vessel	100%	3197.07	1335 / 1335	0%	0	0 / 0
spleen	100%	2307.92	241 / 241	0%	0	0 / 0
heart	100%	1798.25	858 / 861	0%	0	0 / 0
muscle	99%	1532.37	796 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	95%	5.85	76 / 80
tonsil	0%	0	0 / 0	91%	5.42	41 / 45
lymph node	0%	0	0 / 0	79%	3.89	23 / 29
peripheral blood	74%	646.65	685 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0035195	Biological process	miRNA-mediated post-transcriptional gene silencing
GO_1900153	Biological process	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO_0035278	Biological process	miRNA-mediated gene silencing by inhibition of translation
GO_0060213	Biological process	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO_0000932	Cellular component	P-body
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005515	Molecular function	protein binding
GO_0003723	Molecular function	RNA binding

IV. Literature review

[source]

Gene name	TNRC6C
Protein name	Alternative protein TNRC6C Trinucleotide repeat-containing gene 6C protein Trinucleotide repeat containing adaptor 6C
Synonyms	KIAA1582
Description	FUNCTION: Plays a role in RNA-mediated gene silencing by micro-RNAs (miRNAs). Required for miRNA-dependent translational repression of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes. .
Accessions	ENST00000588549.1 Q9HCJ0 A0A1B0GU24 ENST00000636222.1 K7ELY5 K7EKN9 L8EB01 ENST00000585438.1 ENST00000696541.1 [Q9HCJ0-4] ENST00000696270.1 [Q9HCJ0-3]

TNRC6C report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review