Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| endothelial cell | 18 studies | 26% ± 8% | |
| vein endothelial cell | 5 studies | 30% ± 13% | |
| endothelial cell of vascular tree | 5 studies | 25% ± 7% | |
| capillary endothelial cell | 3 studies | 20% ± 1% | |
| macrophage | 3 studies | 18% ± 2% | |
| microglial cell | 3 studies | 23% ± 4% |
Insufficient scRNA-seq data for expression of TNFRSF10D at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| intestine | 100% | 954.59 | 966 / 966 | 96% | 13.67 | 505 / 527 |
| kidney | 100% | 1329.26 | 89 / 89 | 96% | 21.20 | 861 / 901 |
| stomach | 100% | 744.23 | 358 / 359 | 92% | 11.56 | 263 / 286 |
| thymus | 100% | 721.82 | 651 / 653 | 88% | 8.34 | 533 / 605 |
| liver | 100% | 1595.86 | 226 / 226 | 87% | 10.47 | 353 / 406 |
| lung | 100% | 1701.34 | 578 / 578 | 85% | 10.95 | 982 / 1155 |
| esophagus | 96% | 645.64 | 1392 / 1445 | 83% | 11.23 | 152 / 183 |
| pancreas | 88% | 342.05 | 289 / 328 | 91% | 15.94 | 162 / 178 |
| uterus | 99% | 988.15 | 168 / 170 | 76% | 11.42 | 351 / 459 |
| bladder | 100% | 686.52 | 21 / 21 | 65% | 6.75 | 328 / 504 |
| prostate | 100% | 828.49 | 245 / 245 | 54% | 3.18 | 272 / 502 |
| ovary | 100% | 1148.83 | 180 / 180 | 43% | 3.08 | 187 / 430 |
| breast | 100% | 859.38 | 458 / 459 | 39% | 2.80 | 433 / 1118 |
| adrenal gland | 91% | 355.17 | 236 / 258 | 40% | 4.41 | 92 / 230 |
| brain | 53% | 229.31 | 1411 / 2642 | 50% | 3.52 | 355 / 705 |
| skin | 80% | 2330.42 | 1448 / 1809 | 22% | 6.41 | 103 / 472 |
| adipose | 100% | 1250.70 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 100% | 852.09 | 241 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 98% | 789.76 | 1313 / 1335 | 0% | 0 | 0 / 0 |
| heart | 94% | 550.77 | 813 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 93% | 12.10 | 42 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 93% | 8.67 | 27 / 29 |
| peripheral blood | 88% | 501.99 | 816 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 43% | 3.50 | 34 / 80 |
| muscle | 32% | 75.13 | 255 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007165 | Biological process | signal transduction |
| GO_0006915 | Biological process | apoptotic process |
| GO_0043066 | Biological process | negative regulation of apoptotic process |
| GO_0009986 | Cellular component | cell surface |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0004888 | Molecular function | transmembrane signaling receptor activity |
| GO_0045569 | Molecular function | TRAIL binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | TNFRSF10D |
| Protein name | Tumor necrosis factor receptor superfamily member 10D (Decoy receptor 2) (DcR2) (TNF-related apoptosis-inducing ligand receptor 4) (TRAIL receptor 4) (TRAIL-R4) (TRAIL receptor with a truncated death domain) (CD antigen CD264) |
| Synonyms | TRUNDD TRAILR4 DCR2 UNQ251/PRO288 |
| Description | FUNCTION: Receptor for the cytotoxic ligand TRAIL . Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis . Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway . . |
| Accessions | ENST00000312584.4 Q9UBN6 |
